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PubMed code 23437843

Compile data set for download or QSAR
Found 30 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427725
PNG
(CHEMBL2324222)
Show SMILES CNC(=O)\C=C1\COc2c1ccc(OS(=O)(=O)c1ccc(OC)cc1)c2C
Show InChI InChI=1S/C19H19NO6S/c1-12-17(26-27(22,23)15-6-4-14(24-3)5-7-15)9-8-16-13(10-18(21)20-2)11-25-19(12)16/h4-10H,11H2,1-3H3,(H,20,21)/b13-10-
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n/an/a 7n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427724
PNG
(CHEMBL2324223)
Show SMILES CNC(=O)\C=C1\COc2cc(OS(=O)(=O)CCC(F)(F)F)ccc12
Show InChI InChI=1S/C14H14F3NO5S/c1-18-13(19)6-9-8-22-12-7-10(2-3-11(9)12)23-24(20,21)5-4-14(15,16)17/h2-3,6-7H,4-5,8H2,1H3,(H,18,19)/b9-6-
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PubMed
n/an/a 9.10n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427729
PNG
(CHEMBL2324533)
Show SMILES CNC(=O)\C=C1\COc2c1ccc(OS(=O)(=O)c1ccccc1)c2C
Show InChI InChI=1S/C18H17NO5S/c1-12-16(24-25(21,22)14-6-4-3-5-7-14)9-8-15-13(10-17(20)19-2)11-23-18(12)15/h3-10H,11H2,1-2H3,(H,19,20)/b13-10-
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n/an/a 9.80n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427726
PNG
(CHEMBL2324221)
Show SMILES CNC(=O)\C=C1\COc2cc(OS(=O)(=O)c3ccc(OC)cc3)ccc12
Show InChI InChI=1S/C18H17NO6S/c1-19-18(20)9-12-11-24-17-10-14(5-8-16(12)17)25-26(21,22)15-6-3-13(23-2)4-7-15/h3-10H,11H2,1-2H3,(H,19,20)/b12-9-
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n/an/a 11n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427723
PNG
(CHEMBL2324224)
Show SMILES CNC(=O)\C=C1\COc2c1ccc(OS(=O)(=O)CCC(F)(F)F)c2C
Show InChI InChI=1S/C15H16F3NO5S/c1-9-12(24-25(21,22)6-5-15(16,17)18)4-3-11-10(7-13(20)19-2)8-23-14(9)11/h3-4,7H,5-6,8H2,1-2H3,(H,19,20)/b10-7-
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n/an/a 11n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427735
PNG
(CHEMBL2324528)
Show SMILES CNC(=O)\C=C1\COc2cc(OS(=O)(=O)c3ccc(Cl)cc3)ccc12
Show InChI InChI=1S/C17H14ClNO5S/c1-19-17(20)8-11-10-23-16-9-13(4-7-15(11)16)24-25(21,22)14-5-2-12(18)3-6-14/h2-9H,10H2,1H3,(H,19,20)/b11-8-
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n/an/a 12n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427727
PNG
(CHEMBL2324535)
Show SMILES CNC(=O)\C=C1\COc2c1ccc(OS(=O)(=O)c1ccc(cc1)C#N)c2C
Show InChI InChI=1S/C19H16N2O5S/c1-12-17(26-27(23,24)15-5-3-13(10-20)4-6-15)8-7-16-14(9-18(22)21-2)11-25-19(12)16/h3-9H,11H2,1-2H3,(H,21,22)/b14-9-
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n/an/a 15n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427730
PNG
(CHEMBL2324532)
Show SMILES CNC(=O)\C=C1\COc2cc(OS(=O)(=O)c3ccc(Cl)s3)ccc12
Show InChI InChI=1S/C15H12ClNO5S2/c1-17-14(18)6-9-8-21-12-7-10(2-3-11(9)12)22-24(19,20)15-5-4-13(16)23-15/h2-7H,8H2,1H3,(H,17,18)/b9-6-
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n/an/a 16n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427731
PNG
(CHEMBL2324531)
Show SMILES CNC(=O)\C=C1\COc2cc(OS(=O)(=O)c3ccc(cc3)S(C)(=O)=O)ccc12
Show InChI InChI=1S/C18H17NO7S2/c1-19-18(20)9-12-11-25-17-10-13(3-8-16(12)17)26-28(23,24)15-6-4-14(5-7-15)27(2,21)22/h3-10H,11H2,1-2H3,(H,19,20)/b12-9-
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n/an/a 19n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427736
PNG
(CHEMBL2324527)
Show SMILES CNC(=O)\C=C1\COc2cc(OS(=O)(=O)c3cccc(c3)C#N)ccc12
Show InChI InChI=1S/C18H14N2O5S/c1-20-18(21)8-13-11-24-17-9-14(5-6-16(13)17)25-26(22,23)15-4-2-3-12(7-15)10-19/h2-9H,11H2,1H3,(H,20,21)/b13-8-
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n/an/a 19n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427728
PNG
(CHEMBL2324534)
Show SMILES CNC(=O)\C=C1\COc2c1ccc(OS(=O)(=O)c1cccc(Cl)c1)c2C
Show InChI InChI=1S/C18H16ClNO5S/c1-11-16(25-26(22,23)14-5-3-4-13(19)9-14)7-6-15-12(8-17(21)20-2)10-24-18(11)15/h3-9H,10H2,1-2H3,(H,20,21)/b12-8-
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n/an/a 24n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427732
PNG
(CHEMBL2321904)
Show SMILES CNC(=O)C=C1COc2cc(OS(=O)(=O)c3ccc(cc3)C(C)=O)ccc12 |w:4.3|
Show InChI InChI=1S/C19H17NO6S/c1-12(21)13-3-6-16(7-4-13)27(23,24)26-15-5-8-17-14(9-19(22)20-2)11-25-18(17)10-15/h3-10H,11H2,1-2H3,(H,20,22)
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n/an/a 29n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427739
PNG
(CHEMBL2324524)
Show SMILES CNC(=O)\C=C1\COc2cc(OS(=O)(=O)c3ccccc3)ccc12
Show InChI InChI=1S/C17H15NO5S/c1-18-17(19)9-12-11-22-16-10-13(7-8-15(12)16)23-24(20,21)14-5-3-2-4-6-14/h2-10H,11H2,1H3,(H,18,19)/b12-9-
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n/an/a 34n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50427720
PNG
(CHEMBL2324230)
Show SMILES CNC(=O)\C=C1\COc2cc(OCc3cccc(Cl)c3)ccc12
Show InChI InChI=1S/C18H16ClNO3/c1-20-18(21)8-13-11-23-17-9-15(5-6-16(13)17)22-10-12-3-2-4-14(19)7-12/h2-9H,10-11H2,1H3,(H,20,21)/b13-8-
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n/an/a 36n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-B in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427733
PNG
(CHEMBL2324530)
Show SMILES CNC(=O)\C=C1\COc2cc(OS(=O)(=O)c3ccc(cc3)[N+]([O-])=O)ccc12
Show InChI InChI=1S/C17H14N2O7S/c1-18-17(20)8-11-10-25-16-9-13(4-7-15(11)16)26-27(23,24)14-5-2-12(3-6-14)19(21)22/h2-9H,10H2,1H3,(H,18,20)/b11-8-
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n/an/a 37n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427737
PNG
(CHEMBL2324526)
Show SMILES CNC(=O)\C=C1\COc2cc(OS(=O)(=O)c3cccc(F)c3)ccc12
Show InChI InChI=1S/C17H14FNO5S/c1-19-17(20)7-11-10-23-16-9-13(5-6-15(11)16)24-25(21,22)14-4-2-3-12(18)8-14/h2-9H,10H2,1H3,(H,19,20)/b11-7-
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n/an/a 41n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427738
PNG
(CHEMBL2324525)
Show SMILES CNC(=O)\C=C1\COc2cc(OS(=O)(=O)c3cccc(Cl)c3)ccc12
Show InChI InChI=1S/C17H14ClNO5S/c1-19-17(20)7-11-10-23-16-9-13(5-6-15(11)16)24-25(21,22)14-4-2-3-12(18)8-14/h2-9H,10H2,1H3,(H,19,20)/b11-7-
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n/an/a 41n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427734
PNG
(CHEMBL2324529)
Show SMILES CNC(=O)\C=C1\COc2cc(OS(=O)(=O)c3ccc(cc3)C#N)ccc12
Show InChI InChI=1S/C18H14N2O5S/c1-20-18(21)8-13-11-24-17-9-14(4-7-16(13)17)25-26(22,23)15-5-2-12(10-19)3-6-15/h2-9H,11H2,1H3,(H,20,21)/b13-8-
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n/an/a 45n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427718
PNG
(CHEMBL2324232)
Show SMILES CNC(=O)Cc1cc(=O)oc2cc(OS(=O)(=O)c3cccc(Cl)c3)ccc12
Show InChI InChI=1S/C18H14ClNO6S/c1-20-17(21)7-11-8-18(22)25-16-10-13(5-6-15(11)16)26-27(23,24)14-4-2-3-12(19)9-14/h2-6,8-10H,7H2,1H3,(H,20,21)
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n/an/a 111n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50427719
PNG
(CHEMBL2324231)
Show SMILES CNC(=O)Cc1coc2cc(OCc3cccc(Cl)c3)ccc12
Show InChI InChI=1S/C18H16ClNO3/c1-20-18(21)8-13-11-23-17-9-15(5-6-16(13)17)22-10-12-3-2-4-14(19)7-12/h2-7,9,11H,8,10H2,1H3,(H,20,21)
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n/an/a 284n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-B in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427721
PNG
(CHEMBL2324227)
Show SMILES CNC(=O)Cc1coc2cc(OS(=O)(=O)c3cccc(Cl)c3)ccc12
Show InChI InChI=1S/C17H14ClNO5S/c1-19-17(20)7-11-10-23-16-9-13(5-6-15(11)16)24-25(21,22)14-4-2-3-12(18)8-14/h2-6,8-10H,7H2,1H3,(H,19,20)
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n/an/a 409n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427720
PNG
(CHEMBL2324230)
Show SMILES CNC(=O)\C=C1\COc2cc(OCc3cccc(Cl)c3)ccc12
Show InChI InChI=1S/C18H16ClNO3/c1-20-18(21)8-13-11-23-17-9-15(5-6-16(13)17)22-10-12-3-2-4-14(19)7-12/h2-9H,10-11H2,1H3,(H,20,21)/b13-8-
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n/an/a 427n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427716
PNG
(CHEMBL2324234)
Show SMILES NCc1cc(=O)oc2cc(OS(=O)(=O)c3cccc(Cl)c3)ccc12
Show InChI InChI=1S/C16H12ClNO5S/c17-11-2-1-3-13(7-11)24(20,21)23-12-4-5-14-10(9-18)6-16(19)22-15(14)8-12/h1-8H,9,18H2
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n/an/a 997n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50427717
PNG
(CHEMBL2321901)
Show SMILES CNCc1cc(=O)oc2cc(OS(=O)(=O)c3cccc(Cl)c3)ccc12
Show InChI InChI=1S/C17H14ClNO5S/c1-19-10-11-7-17(20)23-16-9-13(5-6-15(11)16)24-25(21,22)14-4-2-3-12(18)8-14/h2-9,19H,10H2,1H3
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n/an/a 1.70E+3n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-B in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427719
PNG
(CHEMBL2324231)
Show SMILES CNC(=O)Cc1coc2cc(OCc3cccc(Cl)c3)ccc12
Show InChI InChI=1S/C18H16ClNO3/c1-20-18(21)8-13-11-23-17-9-15(5-6-16(13)17)22-10-12-3-2-4-14(19)7-12/h2-7,9,11H,8,10H2,1H3,(H,20,21)
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n/an/a 3.10E+3n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50427716
PNG
(CHEMBL2324234)
Show SMILES NCc1cc(=O)oc2cc(OS(=O)(=O)c3cccc(Cl)c3)ccc12
Show InChI InChI=1S/C16H12ClNO5S/c17-11-2-1-3-13(7-11)24(20,21)23-12-4-5-14-10(9-18)6-16(19)22-15(14)8-12/h1-8H,9,18H2
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n/an/a 3.30E+3n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-B in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427722
PNG
(CHEMBL2324225)
Show SMILES CCNC(=O)\C=C1\COc2cc(OS(=O)(=O)c3cccc(Cl)c3)ccc12
Show InChI InChI=1S/C18H16ClNO5S/c1-2-20-18(21)8-12-11-24-17-10-14(6-7-16(12)17)25-26(22,23)15-5-3-4-13(19)9-15/h3-10H,2,11H2,1H3,(H,20,21)/b12-8-
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n/an/a 4.20E+3n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50427717
PNG
(CHEMBL2321901)
Show SMILES CNCc1cc(=O)oc2cc(OS(=O)(=O)c3cccc(Cl)c3)ccc12
Show InChI InChI=1S/C17H14ClNO5S/c1-19-10-11-7-17(20)23-16-9-13(5-6-15(11)16)24-25(21,22)14-4-2-3-12(18)8-14/h2-9,19H,10H2,1H3
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n/an/a 5.30E+3n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50427718
PNG
(CHEMBL2324232)
Show SMILES CNC(=O)Cc1cc(=O)oc2cc(OS(=O)(=O)c3cccc(Cl)c3)ccc12
Show InChI InChI=1S/C18H14ClNO6S/c1-20-17(21)7-11-8-18(22)25-16-10-13(5-6-15(11)16)26-27(23,24)14-4-2-3-12(19)9-14/h2-6,8-10H,7H2,1H3,(H,20,21)
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n/an/a 8.30E+3n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-B in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM15613
PNG
(4-chloro-N-(2-morpholin-4-ylethyl)benzamide | 4-ch...)
Show SMILES Clc1ccc(cc1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C13H17ClN2O2/c14-12-3-1-11(2-4-12)13(17)15-5-6-16-7-9-18-10-8-16/h1-4H,5-10H2,(H,15,17)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...

J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%