Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein mono-ADP-ribosyltransferase PARP3 [R100H] (Homo sapiens (Human)) | BDBM103558 (ME0328) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
Ume£ University | Assay Description Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof... | ACS Chem Biol 8: 1698-703 (2013) Article DOI: 10.1021/cb4002014 BindingDB Entry DOI: 10.7270/Q2668BS1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human)) | BDBM103555 (ME0354) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Ume£ University | Assay Description Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof... | ACS Chem Biol 8: 1698-703 (2013) Article DOI: 10.1021/cb4002014 BindingDB Entry DOI: 10.7270/Q2668BS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human)) | BDBM103557 (ME0327) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ume£ University | Assay Description Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof... | ACS Chem Biol 8: 1698-703 (2013) Article DOI: 10.1021/cb4002014 BindingDB Entry DOI: 10.7270/Q2668BS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein mono-ADP-ribosyltransferase PARP3 [R100H] (Homo sapiens (Human)) | BDBM103556 (ME0355) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ume£ University | Assay Description Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof... | ACS Chem Biol 8: 1698-703 (2013) Article DOI: 10.1021/cb4002014 BindingDB Entry DOI: 10.7270/Q2668BS1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Protein mono-ADP-ribosyltransferase PARP3 [R100H] (Homo sapiens (Human)) | BDBM103554 (STO1131 | US8551988, 39) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ume£ University | Assay Description Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof... | ACS Chem Biol 8: 1698-703 (2013) Article DOI: 10.1021/cb4002014 BindingDB Entry DOI: 10.7270/Q2668BS1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human)) | BDBM103558 (ME0328) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ume£ University | Assay Description Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof... | ACS Chem Biol 8: 1698-703 (2013) Article DOI: 10.1021/cb4002014 BindingDB Entry DOI: 10.7270/Q2668BS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human)) | BDBM103556 (ME0355) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ume£ University | Assay Description Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof... | ACS Chem Biol 8: 1698-703 (2013) Article DOI: 10.1021/cb4002014 BindingDB Entry DOI: 10.7270/Q2668BS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein mono-ADP-ribosyltransferase PARP3 [R100H] (Homo sapiens (Human)) | BDBM103557 (ME0327) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.53E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ume£ University | Assay Description Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof... | ACS Chem Biol 8: 1698-703 (2013) Article DOI: 10.1021/cb4002014 BindingDB Entry DOI: 10.7270/Q2668BS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein mono-ADP-ribosyltransferase PARP3 [R100H] (Homo sapiens (Human)) | BDBM103555 (ME0354) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ume£ University | Assay Description Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof... | ACS Chem Biol 8: 1698-703 (2013) Article DOI: 10.1021/cb4002014 BindingDB Entry DOI: 10.7270/Q2668BS1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |