Affinity Data by PubMed id=23791076

PubMed code 23791076

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate after 60 mins by fluorometric analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Competitive inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 4 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of human USP4 using Ub-AMC as substrate after 60 mins by fluorometric analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50437695 (CHEMBL1923233) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of UCH-L1 in human Z138 cells after 1 hr by immunoblotting analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437695 (CHEMBL1923233) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of USP5 in human Z138 cells after 1 hr by immunoblotting analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (Homo sapiens (Human))	BDBM50437695 (CHEMBL1923233) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of USP9x in human Z138 cells after 1 hr by immunoblotting analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 14 (Homo sapiens (Human))	BDBM50437694 (CHEMBL1410015) Show SMILES Cc1cc(C(=O)CN2CCCC2)c(C)n1-c1ccc(F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of human USP14				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate after 60 mins by fluorometric analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of human UCH-L1 using Ub-AMC as substrate after 60 mins by fluorometric analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%