Affinity Data by PubMed id=23879299

PubMed code 23879299

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50440024 (CHEMBL2425785) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co. , Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]-orexin-A from human OX1 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis				J Med Chem 56: 6371-85 (2013) Article DOI: 10.1021/jm400772t BindingDB Entry DOI: 10.7270/Q2QF8V91
Eisai Co. , Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50440024 (CHEMBL2425785) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co. , Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis				J Med Chem 56: 6371-85 (2013) Article DOI: 10.1021/jm400772t BindingDB Entry DOI: 10.7270/Q2QF8V91
Eisai Co. , Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50440021 (CHEMBL2425788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co. , Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis				J Med Chem 56: 6371-85 (2013) Article DOI: 10.1021/jm400772t BindingDB Entry DOI: 10.7270/Q2QF8V91
Eisai Co. , Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50440022 (CHEMBL2425787) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co. , Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis				J Med Chem 56: 6371-85 (2013) Article DOI: 10.1021/jm400772t BindingDB Entry DOI: 10.7270/Q2QF8V91
Eisai Co. , Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50440025 (CHEMBL2425784) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co. , Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis				J Med Chem 56: 6371-85 (2013) Article DOI: 10.1021/jm400772t BindingDB Entry DOI: 10.7270/Q2QF8V91
Eisai Co. , Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50440025 (CHEMBL2425784) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co. , Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]-orexin-A from human OX1 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis				J Med Chem 56: 6371-85 (2013) Article DOI: 10.1021/jm400772t BindingDB Entry DOI: 10.7270/Q2QF8V91
Eisai Co. , Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50440023 (CHEMBL2425786) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co. , Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis				J Med Chem 56: 6371-85 (2013) Article DOI: 10.1021/jm400772t BindingDB Entry DOI: 10.7270/Q2QF8V91
Eisai Co. , Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50440026 (CHEMBL2425783) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co. , Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis				J Med Chem 56: 6371-85 (2013) Article DOI: 10.1021/jm400772t BindingDB Entry DOI: 10.7270/Q2QF8V91
Eisai Co. , Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50440021 (CHEMBL2425788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co. , Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]-orexin-A from human OX1 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis				J Med Chem 56: 6371-85 (2013) Article DOI: 10.1021/jm400772t BindingDB Entry DOI: 10.7270/Q2QF8V91
Eisai Co. , Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50440022 (CHEMBL2425787) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co. , Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]-orexin-A from human OX1 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis				J Med Chem 56: 6371-85 (2013) Article DOI: 10.1021/jm400772t BindingDB Entry DOI: 10.7270/Q2QF8V91
Eisai Co. , Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50440026 (CHEMBL2425783) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co. , Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]-orexin-A from human OX1 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis				J Med Chem 56: 6371-85 (2013) Article DOI: 10.1021/jm400772t BindingDB Entry DOI: 10.7270/Q2QF8V91
Eisai Co. , Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50440023 (CHEMBL2425786) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co. , Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]-orexin-A from human OX1 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis				J Med Chem 56: 6371-85 (2013) Article DOI: 10.1021/jm400772t BindingDB Entry DOI: 10.7270/Q2QF8V91
Eisai Co. , Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%