BindingDB logo
myBDB logout

PubMed code 24211020

Compile data set for download or QSAR
Found 35 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50007404
PNG
(1-(3-Chloro-phenyl)-4-phenethyl-piperazine | CHEMB...)
Show SMILES Clc1cccc(c1)N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-7-4-8-18(15-17)21-13-11-20(12-14-21)10-9-16-5-2-1-3-6-16/h1-8,15H,9-14H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
 0.0400n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN 35428 from dopamine transporter in rat striatum after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50007410
PNG
(1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Show SMILES Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-8-10-19(11-9-18)22-15-13-21(14-16-22)12-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 0.120n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50494706
PNG
(CHEMBL3093268)
Show SMILES Clc1ccccc1N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-8-4-5-9-18(17)21-14-12-20(13-15-21)11-10-16-6-2-1-3-7-16/h1-9H,10-15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 0.130n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN 35428 from dopamine transporter in rat striatum after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50494706
PNG
(CHEMBL3093268)
Show SMILES Clc1ccccc1N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-8-4-5-9-18(17)21-14-12-20(13-15-21)11-10-16-6-2-1-3-7-16/h1-9H,10-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 0.150n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50494707
PNG
(CHEMBL3093270)
Show SMILES Clc1ccccc1N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-10-4-5-11-19(18)22-15-13-21(14-16-22)12-6-9-17-7-2-1-3-8-17/h1-5,7-8,10-11H,6,9,12-16H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
 0.560n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50494708
PNG
(CHEMBL3093269)
Show SMILES Clc1ccc(cc1)N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-6-8-18(9-7-17)21-14-12-20(13-15-21)11-10-16-4-2-1-3-5-16/h1-9H,10-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
 1.90n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50007412
PNG
(1-(3-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Show SMILES Clc1cccc(c1)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-9-4-10-19(16-18)22-14-12-21(13-15-22)11-5-8-17-6-2-1-3-7-17/h1-4,6-7,9-10,16H,5,8,11-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 4.90n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50494708
PNG
(CHEMBL3093269)
Show SMILES Clc1ccc(cc1)N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-6-8-18(9-7-17)21-14-12-20(13-15-21)11-10-16-4-2-1-3-5-16/h1-9H,10-15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
 6n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN 35428 from dopamine transporter in rat striatum after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50007404
PNG
(1-(3-Chloro-phenyl)-4-phenethyl-piperazine | CHEMB...)
Show SMILES Clc1cccc(c1)N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-7-4-8-18(15-17)21-13-11-20(12-14-21)10-9-16-5-2-1-3-6-16/h1-8,15H,9-14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
 6.5n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50007404
PNG
(1-(3-Chloro-phenyl)-4-phenethyl-piperazine | CHEMB...)
Show SMILES Clc1cccc(c1)N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-7-4-8-18(15-17)21-13-11-20(12-14-21)10-9-16-5-2-1-3-6-16/h1-8,15H,9-14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
 53n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5-HT2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50494706
PNG
(CHEMBL3093268)
Show SMILES Clc1ccccc1N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-8-4-5-9-18(17)21-14-12-20(13-15-21)11-10-16-6-2-1-3-7-16/h1-9H,10-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 67n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](-)-sulpiride from dopamine D2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50494707
PNG
(CHEMBL3093270)
Show SMILES Clc1ccccc1N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-10-4-5-11-19(18)22-15-13-21(14-16-22)12-6-9-17-7-2-1-3-8-17/h1-5,7-8,10-11H,6,9,12-16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
 77n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](-)-sulpiride from dopamine D2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50109383
PNG
(1-(3-Phenyl-propyl)-4-pyridin-2-yl-piperazine | 1-...)
Show SMILES C(CN1CCN(CC1)c1ccccn1)Cc1ccccc1
Show InChI InChI=1S/C18H23N3/c1-2-7-17(8-3-1)9-6-12-20-13-15-21(16-14-20)18-10-4-5-11-19-18/h1-5,7-8,10-11H,6,9,12-16H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 82n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50007412
PNG
(1-(3-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Show SMILES Clc1cccc(c1)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-9-4-10-19(16-18)22-14-12-21(13-15-22)11-5-8-17-6-2-1-3-7-17/h1-4,6-7,9-10,16H,5,8,11-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 128n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](-)-sulpiride from dopamine D2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50007404
PNG
(1-(3-Chloro-phenyl)-4-phenethyl-piperazine | CHEMB...)
Show SMILES Clc1cccc(c1)N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-7-4-8-18(15-17)21-13-11-20(12-14-21)10-9-16-5-2-1-3-6-16/h1-8,15H,9-14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
 327n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](-)-sulpiride from dopamine D2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50494708
PNG
(CHEMBL3093269)
Show SMILES Clc1ccc(cc1)N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-6-8-18(9-7-17)21-14-12-20(13-15-21)11-10-16-4-2-1-3-5-16/h1-9H,10-15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
 372n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from serotonin transporter in rat brainstem after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50007410
PNG
(1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Show SMILES Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-8-10-19(11-9-18)22-15-13-21(14-16-22)12-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 391n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5-HT2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50494707
PNG
(CHEMBL3093270)
Show SMILES Clc1ccccc1N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-10-4-5-11-19(18)22-15-13-21(14-16-22)12-6-9-17-7-2-1-3-8-17/h1-5,7-8,10-11H,6,9,12-16H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
 409n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from serotonin transporter in rat brainstem after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50494707
PNG
(CHEMBL3093270)
Show SMILES Clc1ccccc1N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-10-4-5-11-19(18)22-15-13-21(14-16-22)12-6-9-17-7-2-1-3-8-17/h1-5,7-8,10-11H,6,9,12-16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
 482n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN 35428 from dopamine transporter in rat striatum after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50494706
PNG
(CHEMBL3093268)
Show SMILES Clc1ccccc1N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-8-4-5-9-18(17)21-14-12-20(13-15-21)11-10-16-6-2-1-3-7-16/h1-9H,10-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 484n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5-HT2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50007412
PNG
(1-(3-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Show SMILES Clc1cccc(c1)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-9-4-10-19(16-18)22-14-12-21(13-15-22)11-5-8-17-6-2-1-3-7-17/h1-4,6-7,9-10,16H,5,8,11-15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 488n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from serotonin transporter in rat brainstem after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50007412
PNG
(1-(3-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Show SMILES Clc1cccc(c1)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-9-4-10-19(16-18)22-14-12-21(13-15-22)11-5-8-17-6-2-1-3-7-17/h1-4,6-7,9-10,16H,5,8,11-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 498n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5-HT2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50494708
PNG
(CHEMBL3093269)
Show SMILES Clc1ccc(cc1)N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-6-8-18(9-7-17)21-14-12-20(13-15-21)11-10-16-4-2-1-3-5-16/h1-9H,10-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
 518n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5-HT2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50007410
PNG
(1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Show SMILES Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-8-10-19(11-9-18)22-15-13-21(14-16-22)12-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 660n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](-)-sulpiride from dopamine D2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50007404
PNG
(1-(3-Chloro-phenyl)-4-phenethyl-piperazine | CHEMB...)
Show SMILES Clc1cccc(c1)N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-7-4-8-18(15-17)21-13-11-20(12-14-21)10-9-16-5-2-1-3-6-16/h1-8,15H,9-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
 802n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from serotonin transporter in rat brainstem after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50494708
PNG
(CHEMBL3093269)
Show SMILES Clc1ccc(cc1)N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-6-8-18(9-7-17)21-14-12-20(13-15-21)11-10-16-4-2-1-3-5-16/h1-9H,10-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
 834n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](-)-sulpiride from dopamine D2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50109383
PNG
(1-(3-Phenyl-propyl)-4-pyridin-2-yl-piperazine | 1-...)
Show SMILES C(CN1CCN(CC1)c1ccccn1)Cc1ccccc1
Show InChI InChI=1S/C18H23N3/c1-2-7-17(8-3-1)9-6-12-20-13-15-21(16-14-20)18-10-4-5-11-19-18/h1-5,7-8,10-11H,6,9,12-16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 940n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H](-)-sulpiride from dopamine D2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50494707
PNG
(CHEMBL3093270)
Show SMILES Clc1ccccc1N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-10-4-5-11-19(18)22-15-13-21(14-16-22)12-6-9-17-7-2-1-3-8-17/h1-5,7-8,10-11H,6,9,12-16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
 952n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5-HT2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50007410
PNG
(1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Show SMILES Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-8-10-19(11-9-18)22-15-13-21(14-16-22)12-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 1.10E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from serotonin transporter in rat brainstem after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50109383
PNG
(1-(3-Phenyl-propyl)-4-pyridin-2-yl-piperazine | 1-...)
Show SMILES C(CN1CCN(CC1)c1ccccn1)Cc1ccccc1
Show InChI InChI=1S/C18H23N3/c1-2-7-17(8-3-1)9-6-12-20-13-15-21(16-14-20)18-10-4-5-11-19-18/h1-5,7-8,10-11H,6,9,12-16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 1.24E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5-HT2 receptor in rat brain after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50007410
PNG
(1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Show SMILES Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-8-10-19(11-9-18)22-15-13-21(14-16-22)12-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 2.65E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN 35428 from dopamine transporter in rat striatum after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50109383
PNG
(1-(3-Phenyl-propyl)-4-pyridin-2-yl-piperazine | 1-...)
Show SMILES C(CN1CCN(CC1)c1ccccn1)Cc1ccccc1
Show InChI InChI=1S/C18H23N3/c1-2-7-17(8-3-1)9-6-12-20-13-15-21(16-14-20)18-10-4-5-11-19-18/h1-5,7-8,10-11H,6,9,12-16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 9.15E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN 35428 from dopamine transporter in rat striatum after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50109383
PNG
(1-(3-Phenyl-propyl)-4-pyridin-2-yl-piperazine | 1-...)
Show SMILES C(CN1CCN(CC1)c1ccccn1)Cc1ccccc1
Show InChI InChI=1S/C18H23N3/c1-2-7-17(8-3-1)9-6-12-20-13-15-21(16-14-20)18-10-4-5-11-19-18/h1-5,7-8,10-11H,6,9,12-16H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from serotonin transporter in rat brainstem after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50007412
PNG
(1-(3-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Show SMILES Clc1cccc(c1)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C19H23ClN2/c20-18-9-4-10-19(16-18)22-14-12-21(13-15-22)11-5-8-17-6-2-1-3-7-17/h1-4,6-7,9-10,16H,5,8,11-15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN 35428 from dopamine transporter in rat striatum after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50494706
PNG
(CHEMBL3093268)
Show SMILES Clc1ccccc1N1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C18H21ClN2/c19-17-8-4-5-9-18(17)21-14-12-20(13-15-21)11-10-16-6-2-1-3-7-16/h1-9H,10-15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from serotonin transporter in rat brainstem after 120 mins by liquid scintillation counting analysis

Bioorg Med Chem Lett 23: 6920-6922 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.038
BindingDB Entry DOI: 10.7270/Q2J969B5
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%