Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50017961 (CHEMBL3289346) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Salerno Curated by ChEMBL | Assay Description Inhibition of mPGES-1 in interleukin-1 beta-stimulated human A549 cell microsomes assessed as reduction in PGE2 production using PGH2 as substrate tr... | Eur J Med Chem 80: 407-15 (2014) Article DOI: 10.1016/j.ejmech.2014.04.061 BindingDB Entry DOI: 10.7270/Q28S4RGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50017962 (CHEMBL3289347) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Salerno Curated by ChEMBL | Assay Description Inhibition of mPGES-1 in interleukin-1 beta-stimulated human A549 cell microsomes assessed as reduction in PGE2 production using PGH2 as substrate tr... | Eur J Med Chem 80: 407-15 (2014) Article DOI: 10.1016/j.ejmech.2014.04.061 BindingDB Entry DOI: 10.7270/Q28S4RGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50017963 (CHEMBL3289348) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Salerno Curated by ChEMBL | Assay Description Inhibition of mPGES-1 in interleukin-1 beta-stimulated human A549 cell microsomes assessed as reduction in PGE2 production using PGH2 as substrate tr... | Eur J Med Chem 80: 407-15 (2014) Article DOI: 10.1016/j.ejmech.2014.04.061 BindingDB Entry DOI: 10.7270/Q28S4RGX | |||||||||||
More data for this Ligand-Target Pair |