Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50345695 (5-(Dimethylamino)-N-{4-[2-{4-[4-(1-naphthyl)pipera...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in EBNA gene-positive HEK293 cells after 120 mins | ACS Med Chem Lett 1: 249-253 (2010) Article DOI: 10.1021/ml100053y BindingDB Entry DOI: 10.7270/Q2HD7W0T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50345703 (8-{4-[4-(1,3-Dioxotetrahydro-1H-pyrrolo[1,2-c]imid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in EBNA gene-positive HEK293 cells after 120 mins | ACS Med Chem Lett 1: 249-253 (2010) Article DOI: 10.1021/ml100053y BindingDB Entry DOI: 10.7270/Q2HD7W0T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50126474 (2-[4-(4-Naphthalen-1-yl-piperazin-1-yl)-butyl]-tet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in EBNA gene-positive HEK293 cells after 120 mins | ACS Med Chem Lett 1: 249-253 (2010) Article DOI: 10.1021/ml100053y BindingDB Entry DOI: 10.7270/Q2HD7W0T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50345697 (5-(Dimethylamino)-N-{7-[2-{4-[4-(1-naphthyl)pipera...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in EBNA gene-positive HEK293 cells after 120 mins | ACS Med Chem Lett 1: 249-253 (2010) Article DOI: 10.1021/ml100053y BindingDB Entry DOI: 10.7270/Q2HD7W0T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50054395 (2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in EBNA gene-positive HEK293 cells after 120 mins | ACS Med Chem Lett 1: 249-253 (2010) Article DOI: 10.1021/ml100053y BindingDB Entry DOI: 10.7270/Q2HD7W0T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50345698 (5-(Dimethylamino)-N-[5-({2-[2-{4-[4-(2-methoxyphen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in EBNA gene-positive HEK293 cells after 120 mins | ACS Med Chem Lett 1: 249-253 (2010) Article DOI: 10.1021/ml100053y BindingDB Entry DOI: 10.7270/Q2HD7W0T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50345699 (5-(Dimethylamino)-N-[5-({4-[2-{4-[4-(2-methoxyphen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in EBNA gene-positive HEK293 cells after 120 mins | ACS Med Chem Lett 1: 249-253 (2010) Article DOI: 10.1021/ml100053y BindingDB Entry DOI: 10.7270/Q2HD7W0T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50345694 (5-(Dimethylamino)-N-{4-[2-{4-[4-(2-methoxyphenyl)p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in EBNA gene-positive HEK293 cells after 120 mins | ACS Med Chem Lett 1: 249-253 (2010) Article DOI: 10.1021/ml100053y BindingDB Entry DOI: 10.7270/Q2HD7W0T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50345696 (5-(Dimethylamino)-N-{7-[2-{4-[4-(2-methoxyphenyl)p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in EBNA gene-positive HEK293 cells after 120 mins | ACS Med Chem Lett 1: 249-253 (2010) Article DOI: 10.1021/ml100053y BindingDB Entry DOI: 10.7270/Q2HD7W0T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50345695 (5-(Dimethylamino)-N-{4-[2-{4-[4-(1-naphthyl)pipera...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to human 5HT1A receptor expressed in CHO cells after 10 mins by confocal microscopy | ACS Med Chem Lett 1: 249-253 (2010) Article DOI: 10.1021/ml100053y BindingDB Entry DOI: 10.7270/Q2HD7W0T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50345702 (5-{4-[4-(1,3-Dioxotetrahydro-1H-pyrrolo[1,2-c]imid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in EBNA gene-positive HEK293 cells after 120 mins | ACS Med Chem Lett 1: 249-253 (2010) Article DOI: 10.1021/ml100053y BindingDB Entry DOI: 10.7270/Q2HD7W0T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50345701 (5-{4-[4-(1,3-Dioxotetrahydro-1H-pyrrolo[1,2-c]imid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in EBNA gene-positive HEK293 cells after 120 mins | ACS Med Chem Lett 1: 249-253 (2010) Article DOI: 10.1021/ml100053y BindingDB Entry DOI: 10.7270/Q2HD7W0T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50345700 (2-[4-(4-{5-(Dimethylamino)-1-naphthylsulfonyl}pipe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in EBNA gene-positive HEK293 cells after 120 mins | ACS Med Chem Lett 1: 249-253 (2010) Article DOI: 10.1021/ml100053y BindingDB Entry DOI: 10.7270/Q2HD7W0T | |||||||||||
More data for this Ligand-Target Pair |