Affinity Data by PubMed id=24929290

PubMed code 24929290

Found 19 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50330988 ((3-hydroxyphenyl)(5-(3-hydroxyphenyl)thiophen-2-yl...) Show SMILES Oc1cccc(c1)C(=O)c1ccc(s1)-c1cccc(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate after 10 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50023153 (CHEMBL3298951) Show SMILES OCc1cccc(c1)-c1ccc(s1)C(=O)c1cccc(O)c1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD2 microsomal fraction using [2, 4, 6, 7-3H]-estradiol as substrate after 20 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50023153 (CHEMBL3298951) Show SMILES OCc1cccc(c1)-c1ccc(s1)C(=O)c1cccc(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate after 10 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50023157 (CHEMBL3298955) Show SMILES Oc1cccc(Sc2ccc(s2)C(=O)c2cccc(O)c2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate after 10 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50330988 ((3-hydroxyphenyl)(5-(3-hydroxyphenyl)thiophen-2-yl...) Show SMILES Oc1cccc(c1)C(=O)c1ccc(s1)-c1cccc(O)c1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD2 microsomal fraction using [2, 4, 6, 7-3H]-estradiol as substrate after 20 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50023155 (CHEMBL3298953) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate after 10 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50023156 (CHEMBL3298954) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate after 10 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50023154 (CHEMBL3298952) Show SMILES OCc1ccc(cc1)-c1ccc(s1)C(=O)c1cccc(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate after 10 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM25851 (3-[5-(3-hydroxyphenyl)thiophen-2-yl]phenol \| hydro...) Show SMILES Oc1cccc(c1)-c1ccc(s1)-c1cccc(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate after 10 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50023154 (CHEMBL3298952) Show SMILES OCc1ccc(cc1)-c1ccc(s1)C(=O)c1cccc(O)c1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD2 microsomal fraction using [2, 4, 6, 7-3H]-estradiol as substrate after 20 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50023155 (CHEMBL3298953) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD2 microsomal fraction using [2, 4, 6, 7-3H]-estradiol as substrate after 20 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50023157 (CHEMBL3298955) Show SMILES Oc1cccc(Sc2ccc(s2)C(=O)c2cccc(O)c2)c1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD2 microsomal fraction using [2, 4, 6, 7-3H]-estradiol as substrate after 20 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50023159 (CHEMBL3298957) Show SMILES Oc1ccc(cc1)C(=O)c1ccc(Sc2cccc(O)c2)s1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	247	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD2 microsomal fraction using [2, 4, 6, 7-3H]-estradiol as substrate after 20 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50023158 (CHEMBL3298956) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate after 10 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50023158 (CHEMBL3298956) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	283	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD2 microsomal fraction using [2, 4, 6, 7-3H]-estradiol as substrate after 20 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50023160 (CHEMBL3297755) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	389	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD2 microsomal fraction using [2, 4, 6, 7-3H]-estradiol as substrate after 20 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50023160 (CHEMBL3297755) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate after 10 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50023159 (CHEMBL3298957) Show SMILES Oc1ccc(cc1)C(=O)c1ccc(Sc2cccc(O)c2)s1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	752	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate after 10 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50023156 (CHEMBL3298954) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	836	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD2 microsomal fraction using [2, 4, 6, 7-3H]-estradiol as substrate after 20 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%