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PubMed code 25699156

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50081058
PNG
(CHEMBL3421842 | US10166214, Example 22 | US1067526...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)cc2ccccc12 |r|
Show InChI InChI=1S/C19H23N3O/c1-11-8-12-6-4-5-7-13(12)17(21-11)19(2,3)22-18(23)16-14-9-20-10-15(14)16/h4-8,14-16,20H,9-10H2,1-3H3,(H,22,23)/t14-,15+,16+
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 3.70n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 4 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50081055
PNG
(CHEMBL3421843 | US10166214, Example 49 | US1067526...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nn(C)c2ccccc12 |r|
Show InChI InChI=1S/C17H22N4O/c1-17(2,19-16(22)14-11-8-18-9-12(11)14)15-10-6-4-5-7-13(10)21(3)20-15/h4-7,11-12,14,18H,8-9H2,1-3H3,(H,19,22)/t11-,12+,14+
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 4.5n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 4 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50081060
PNG
(CHEMBL3421844 | US10166214, Example 101 | US106752...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1noc2c(F)cccc12 |r|
Show InChI InChI=1S/C16H18FN3O2/c1-16(2,19-15(21)12-9-6-18-7-10(9)12)14-8-4-3-5-11(17)13(8)22-20-14/h3-5,9-10,12,18H,6-7H2,1-2H3,(H,19,21)/t9-,10+,12+
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 46n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 4 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50081059
PNG
(CHEMBL3421845 | US10166214, Example 138 | US106752...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r|
Show InChI InChI=1S/C18H22N4O/c1-10-20-14-7-5-4-6-11(14)16(21-10)18(2,3)22-17(23)15-12-8-19-9-13(12)15/h4-7,12-13,15,19H,8-9H2,1-3H3,(H,22,23)/t12-,13+,15+
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 70n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 4 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))		BDBM50081058
PNG
(CHEMBL3421842 | US10166214, Example 22 | US1067526...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)cc2ccccc12 |r|
Show InChI InChI=1S/C19H23N3O/c1-11-8-12-6-4-5-7-13(12)17(21-11)19(2,3)22-18(23)16-14-9-20-10-15(14)16/h4-8,14-16,20H,9-10H2,1-3H3,(H,22,23)/t14-,15+,16+
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 848n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))		BDBM50081055
PNG
(CHEMBL3421843 | US10166214, Example 49 | US1067526...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nn(C)c2ccccc12 |r|
Show InChI InChI=1S/C17H22N4O/c1-17(2,19-16(22)14-11-8-18-9-12(11)14)15-10-6-4-5-7-13(10)21(3)20-15/h4-7,11-12,14,18H,8-9H2,1-3H3,(H,19,22)/t11-,12+,14+
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 4.54E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))		BDBM50081059
PNG
(CHEMBL3421845 | US10166214, Example 138 | US106752...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r|
Show InChI InChI=1S/C18H22N4O/c1-10-20-14-7-5-4-6-11(14)16(21-10)18(2,3)22-17(23)15-12-8-19-9-13(12)15/h4-7,12-13,15,19H,8-9H2,1-3H3,(H,22,23)/t12-,13+,15+
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PubMed
 7.36E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))		BDBM50081058
PNG
(CHEMBL3421842 | US10166214, Example 22 | US1067526...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)cc2ccccc12 |r|
Show InChI InChI=1S/C19H23N3O/c1-11-8-12-6-4-5-7-13(12)17(21-11)19(2,3)22-18(23)16-14-9-20-10-15(14)16/h4-8,14-16,20H,9-10H2,1-3H3,(H,22,23)/t14-,15+,16+
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>8.58E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 3 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))		BDBM50081060
PNG
(CHEMBL3421844 | US10166214, Example 101 | US106752...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1noc2c(F)cccc12 |r|
Show InChI InChI=1S/C16H18FN3O2/c1-16(2,19-15(21)12-9-6-18-7-10(9)12)14-8-4-3-5-11(17)13(8)22-20-14/h3-5,9-10,12,18H,6-7H2,1-2H3,(H,19,21)/t9-,10+,12+
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>8.60E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 3 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))		BDBM50081055
PNG
(CHEMBL3421843 | US10166214, Example 49 | US1067526...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nn(C)c2ccccc12 |r|
Show InChI InChI=1S/C17H22N4O/c1-17(2,19-16(22)14-11-8-18-9-12(11)14)15-10-6-4-5-7-13(10)21(3)20-15/h4-7,11-12,14,18H,8-9H2,1-3H3,(H,19,22)/t11-,12+,14+
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>8.62E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 3 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))		BDBM50081059
PNG
(CHEMBL3421845 | US10166214, Example 138 | US106752...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r|
Show InChI InChI=1S/C18H22N4O/c1-10-20-14-7-5-4-6-11(14)16(21-10)18(2,3)22-17(23)15-12-8-19-9-13(12)15/h4-7,12-13,15,19H,8-9H2,1-3H3,(H,22,23)/t12-,13+,15+
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>8.71E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 3 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))		BDBM50081060
PNG
(CHEMBL3421844 | US10166214, Example 101 | US106752...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1noc2c(F)cccc12 |r|
Show InChI InChI=1S/C16H18FN3O2/c1-16(2,19-15(21)12-9-6-18-7-10(9)12)14-8-4-3-5-11(17)13(8)22-20-14/h3-5,9-10,12,18H,6-7H2,1-2H3,(H,19,21)/t9-,10+,12+
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>9.09E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50081058
PNG
(CHEMBL3421842 | US10166214, Example 22 | US1067526...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)cc2ccccc12 |r|
Show InChI InChI=1S/C19H23N3O/c1-11-8-12-6-4-5-7-13(12)17(21-11)19(2,3)22-18(23)16-14-9-20-10-15(14)16/h4-8,14-16,20H,9-10H2,1-3H3,(H,22,23)/t14-,15+,16+
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>9.59E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 2 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50081055
PNG
(CHEMBL3421843 | US10166214, Example 49 | US1067526...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nn(C)c2ccccc12 |r|
Show InChI InChI=1S/C17H22N4O/c1-17(2,19-16(22)14-11-8-18-9-12(11)14)15-10-6-4-5-7-13(10)21(3)20-15/h4-7,11-12,14,18H,8-9H2,1-3H3,(H,19,22)/t11-,12+,14+
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>9.60E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 2 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50081060
PNG
(CHEMBL3421844 | US10166214, Example 101 | US106752...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1noc2c(F)cccc12 |r|
Show InChI InChI=1S/C16H18FN3O2/c1-16(2,19-15(21)12-9-6-18-7-10(9)12)14-8-4-3-5-11(17)13(8)22-20-14/h3-5,9-10,12,18H,6-7H2,1-2H3,(H,19,21)/t9-,10+,12+
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>9.60E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 2 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50081059
PNG
(CHEMBL3421845 | US10166214, Example 138 | US106752...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r|
Show InChI InChI=1S/C18H22N4O/c1-10-20-14-7-5-4-6-11(14)16(21-10)18(2,3)22-17(23)15-12-8-19-9-13(12)15/h4-7,12-13,15,19H,8-9H2,1-3H3,(H,22,23)/t12-,13+,15+
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>9.63E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 2 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))		BDBM50081058
PNG
(CHEMBL3421842 | US10166214, Example 22 | US1067526...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)cc2ccccc12 |r|
Show InChI InChI=1S/C19H23N3O/c1-11-8-12-6-4-5-7-13(12)17(21-11)19(2,3)22-18(23)16-14-9-20-10-15(14)16/h4-8,14-16,20H,9-10H2,1-3H3,(H,22,23)/t14-,15+,16+
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>9.85E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 5 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))		BDBM50081060
PNG
(CHEMBL3421844 | US10166214, Example 101 | US106752...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1noc2c(F)cccc12 |r|
Show InChI InChI=1S/C16H18FN3O2/c1-16(2,19-15(21)12-9-6-18-7-10(9)12)14-8-4-3-5-11(17)13(8)22-20-14/h3-5,9-10,12,18H,6-7H2,1-2H3,(H,19,21)/t9-,10+,12+
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>9.85E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 5 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))		BDBM50081055
PNG
(CHEMBL3421843 | US10166214, Example 49 | US1067526...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nn(C)c2ccccc12 |r|
Show InChI InChI=1S/C17H22N4O/c1-17(2,19-16(22)14-11-8-18-9-12(11)14)15-10-6-4-5-7-13(10)21(3)20-15/h4-7,11-12,14,18H,8-9H2,1-3H3,(H,19,22)/t11-,12+,14+
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>9.86E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 5 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))		BDBM50081059
PNG
(CHEMBL3421845 | US10166214, Example 138 | US106752...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r|
Show InChI InChI=1S/C18H22N4O/c1-10-20-14-7-5-4-6-11(14)16(21-10)18(2,3)22-17(23)15-12-8-19-9-13(12)15/h4-7,12-13,15,19H,8-9H2,1-3H3,(H,22,23)/t12-,13+,15+
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>9.86E+3n/an/an/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 5 receptor expressed in CHO cell membranes incubated for 180 mi...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50081059
PNG
(CHEMBL3421845 | US10166214, Example 138 | US106752...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r|
Show InChI InChI=1S/C18H22N4O/c1-10-20-14-7-5-4-6-11(14)16(21-10)18(2,3)22-17(23)15-12-8-19-9-13(12)15/h4-7,12-13,15,19H,8-9H2,1-3H3,(H,22,23)/t12-,13+,15+
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n/an/an/an/a 4.30n/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human somatostatin 4 receptor expressed in H4 cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation i...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50081058
PNG
(CHEMBL3421842 | US10166214, Example 22 | US1067526...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)cc2ccccc12 |r|
Show InChI InChI=1S/C19H23N3O/c1-11-8-12-6-4-5-7-13(12)17(21-11)19(2,3)22-18(23)16-14-9-20-10-15(14)16/h4-8,14-16,20H,9-10H2,1-3H3,(H,22,23)/t14-,15+,16+
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n/an/an/an/a 0.400n/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human somatostatin 4 receptor expressed in H4 cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation i...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50081055
PNG
(CHEMBL3421843 | US10166214, Example 49 | US1067526...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nn(C)c2ccccc12 |r|
Show InChI InChI=1S/C17H22N4O/c1-17(2,19-16(22)14-11-8-18-9-12(11)14)15-10-6-4-5-7-13(10)21(3)20-15/h4-7,11-12,14,18H,8-9H2,1-3H3,(H,19,22)/t11-,12+,14+
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n/an/an/an/a 0.400n/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human somatostatin 4 receptor expressed in H4 cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation i...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50081060
PNG
(CHEMBL3421844 | US10166214, Example 101 | US106752...)
Show SMILES [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1noc2c(F)cccc12 |r|
Show InChI InChI=1S/C16H18FN3O2/c1-16(2,19-15(21)12-9-6-18-7-10(9)12)14-8-4-3-5-11(17)13(8)22-20-14/h3-5,9-10,12,18H,6-7H2,1-2H3,(H,19,21)/t9-,10+,12+
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n/an/an/an/a 1.20n/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human somatostatin 4 receptor expressed in H4 cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation i...

ACS Med Chem Lett 6: 110-1 (2015)


Article DOI: 10.1021/ml500538a
BindingDB Entry DOI: 10.7270/Q2MC91RP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%