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PubMed code 25817240

Compile data set for download or QSAR
Found 33 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067349
PNG
(CHEMBL3401782)
Show SMILES Oc1cccc(Nc2ncnc3sc(cc23)-c2ccccc2)c1
Show InChI InChI=1S/C18H13N3OS/c22-14-8-4-7-13(9-14)21-17-15-10-16(12-5-2-1-3-6-12)23-18(15)20-11-19-17/h1-11,22H,(H,19,20,21)
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n/an/a 160n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067348
PNG
(CHEMBL3401781)
Show SMILES Oc1cccc(Nc2ncnc3scc(-c4ccccc4)c23)c1
Show InChI InChI=1S/C18H13N3OS/c22-14-8-4-7-13(9-14)21-17-16-15(12-5-2-1-3-6-12)10-23-18(16)20-11-19-17/h1-11,22H,(H,19,20,21)
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n/an/a 180n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067347
PNG
(CHEMBL3401780)
Show SMILES CC1CCc2sc3ncnc(Nc4cccc(O)c4)c3c2C1
Show InChI InChI=1S/C17H17N3OS/c1-10-5-6-14-13(7-10)15-16(18-9-19-17(15)22-14)20-11-3-2-4-12(21)8-11/h2-4,8-10,21H,5-7H2,1H3,(H,18,19,20)
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n/an/a 450n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067345
PNG
(CHEMBL3401778)
Show SMILES Oc1cccc(Nc2ncnc3scc(-c4ccc(Cl)cc4)c23)c1
Show InChI InChI=1S/C18H12ClN3OS/c19-12-6-4-11(5-7-12)15-9-24-18-16(15)17(20-10-21-18)22-13-2-1-3-14(23)8-13/h1-10,23H,(H,20,21,22)
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n/an/a 500n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067346
PNG
(CHEMBL3401779)
Show SMILES CCOC(=O)c1sc2ncnc(Nc3cccc(O)c3)c2c1C
Show InChI InChI=1S/C16H15N3O3S/c1-3-22-16(21)13-9(2)12-14(17-8-18-15(12)23-13)19-10-5-4-6-11(20)7-10/h4-8,20H,3H2,1-2H3,(H,17,18,19)
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n/an/a 500n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067344
PNG
(CHEMBL3401777)
Show SMILES Cc1ccc(cc1)-c1csc2ncnc(Nc3cccc(O)c3)c12
Show InChI InChI=1S/C19H15N3OS/c1-12-5-7-13(8-6-12)16-10-24-19-17(16)18(20-11-21-19)22-14-3-2-4-15(23)9-14/h2-11,23H,1H3,(H,20,21,22)
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n/an/a 700n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067341
PNG
(CHEMBL3401775)
Show SMILES Oc1ccc(Nc2ncnc3sc(cc23)-c2ccccc2)cc1
Show InChI InChI=1S/C18H13N3OS/c22-14-8-6-13(7-9-14)21-17-15-10-16(12-4-2-1-3-5-12)23-18(15)20-11-19-17/h1-11,22H,(H,19,20,21)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067340
PNG
(CHEMBL3401774)
Show SMILES Cc1sc2ncnc(Nc3ccc(O)cc3)c2c1-c1ccccc1
Show InChI InChI=1S/C19H15N3OS/c1-12-16(13-5-3-2-4-6-13)17-18(20-11-21-19(17)24-12)22-14-7-9-15(23)10-8-14/h2-11,23H,1H3,(H,20,21,22)
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n/an/a 1.25E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067330
PNG
(CHEMBL3401765)
Show SMILES Fc1ccc(Nc2ncnc3sc4CCCCCc4c23)cc1Cl
Show InChI InChI=1S/C17H15ClFN3S/c18-12-8-10(6-7-13(12)19)22-16-15-11-4-2-1-3-5-14(11)23-17(15)21-9-20-16/h6-9H,1-5H2,(H,20,21,22)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067339
PNG
(CHEMBL1626011)
Show SMILES Oc1ccc(Nc2ncnc3scc(-c4ccccc4)c23)cc1
Show InChI InChI=1S/C18H13N3OS/c22-14-8-6-13(7-9-14)21-17-16-15(12-4-2-1-3-5-12)10-23-18(16)20-11-19-17/h1-11,22H,(H,19,20,21)
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n/an/a 1.66E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067336
PNG
(CHEMBL3401771)
Show SMILES COc1cccc(Nc2ncnc3scc(-c4ccccc4)c23)c1
Show InChI InChI=1S/C19H15N3OS/c1-23-15-9-5-8-14(10-15)22-18-17-16(13-6-3-2-4-7-13)11-24-19(17)21-12-20-18/h2-12H,1H3,(H,20,21,22)
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n/an/a 2.50E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067342
PNG
(CHEMBL3401776)
Show SMILES Oc1ccc(Nc2ncnc3scc(-c4ccc(Cl)cc4)c23)cc1
Show InChI InChI=1S/C18H12ClN3OS/c19-12-3-1-11(2-4-12)15-9-24-18-16(15)17(20-10-21-18)22-13-5-7-14(23)8-6-13/h1-10,23H,(H,20,21,22)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067332
PNG
(CHEMBL3401767)
Show SMILES COc1ccc(Nc2ncnc3scc(-c4ccccc4)c23)cc1
Show InChI InChI=1S/C19H15N3OS/c1-23-15-9-7-14(8-10-15)22-18-17-16(13-5-3-2-4-6-13)11-24-19(17)21-12-20-18/h2-12H,1H3,(H,20,21,22)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067323
PNG
(CHEMBL3237080)
Show SMILES Fc1ccc(Nc2ncnc3sc4CCCCc4c23)cc1
Show InChI InChI=1S/C16H14FN3S/c17-10-5-7-11(8-6-10)20-15-14-12-3-1-2-4-13(12)21-16(14)19-9-18-15/h5-9H,1-4H2,(H,18,19,20)
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n/an/a 3.20E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067229
PNG
(CHEMBL3400599)
Show SMILES Fc1ccccc1Nc1ncnc2sc3CCCCCc3c12
Show InChI InChI=1S/C17H16FN3S/c18-12-7-4-5-8-13(12)21-16-15-11-6-2-1-3-9-14(11)22-17(15)20-10-19-16/h4-5,7-8,10H,1-3,6,9H2,(H,19,20,21)
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n/an/a 4.30E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067322
PNG
(CHEMBL3401762)
Show SMILES Fc1ccc(Nc2ncnc3sc(cc23)-c2ccccc2)cc1
Show InChI InChI=1S/C18H12FN3S/c19-13-6-8-14(9-7-13)22-17-15-10-16(12-4-2-1-3-5-12)23-18(15)21-11-20-17/h1-11H,(H,20,21,22)
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n/an/a 4.30E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067338
PNG
(CHEMBL3401773)
Show SMILES Cc1nc(Nc2ccc(O)cc2)c2cc(sc2n1)-c1ccccc1
Show InChI InChI=1S/C19H15N3OS/c1-12-20-18(22-14-7-9-15(23)10-8-14)16-11-17(24-19(16)21-12)13-5-3-2-4-6-13/h2-11,23H,1H3,(H,20,21,22)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067333
PNG
(CHEMBL3401768)
Show SMILES COc1ccc(Nc2ncnc3scc(-c4ccc(C)cc4)c23)cc1
Show InChI InChI=1S/C20H17N3OS/c1-13-3-5-14(6-4-13)17-11-25-20-18(17)19(21-12-22-20)23-15-7-9-16(24-2)10-8-15/h3-12H,1-2H3,(H,21,22,23)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM60882
PNG
(4-(6-Methyl-thieno[2,3-d]pyrimidin-4-ylamino)-phen...)
Show SMILES Cc1cc2c(Nc3ccc(O)cc3)ncnc2s1
Show InChI InChI=1S/C13H11N3OS/c1-8-6-11-12(14-7-15-13(11)18-8)16-9-2-4-10(17)5-3-9/h2-7,17H,1H3,(H,14,15,16)
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n/an/a 5.60E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067262
PNG
(CHEMBL3401761)
Show SMILES Fc1ccc(Nc2ncnc3scc(-c4ccccc4)c23)cc1
Show InChI InChI=1S/C18H12FN3S/c19-13-6-8-14(9-7-13)22-17-16-15(12-4-2-1-3-5-12)10-23-18(16)21-11-20-17/h1-11H,(H,20,21,22)
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n/an/a 6.30E+3n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067327
PNG
(CHEMBL3401764)
Show SMILES Cc1ccc(cc1)-c1csc2ncnc(Nc3cccc(c3)C(O)=O)c12
Show InChI InChI=1S/C20H15N3O2S/c1-12-5-7-13(8-6-12)16-10-26-19-17(16)18(21-11-22-19)23-15-4-2-3-14(9-15)20(24)25/h2-11H,1H3,(H,24,25)(H,21,22,23)
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n/an/a 1.10E+4n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067343
PNG
(CHEMBL1574987)
Show SMILES CCOc1ccc(cc1)-c1csc2ncnc(Nc3cccc(O)c3)c12
Show InChI InChI=1S/C20H17N3O2S/c1-2-25-16-8-6-13(7-9-16)17-11-26-20-18(17)19(21-12-22-20)23-14-4-3-5-15(24)10-14/h3-12,24H,2H2,1H3,(H,21,22,23)
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n/an/a 1.25E+4n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067231
PNG
(CHEMBL3401759)
Show SMILES Fc1ccccc1Nc1ncnc2sc(cc12)-c1ccccc1
Show InChI InChI=1S/C18H12FN3S/c19-14-8-4-5-9-15(14)22-17-13-10-16(12-6-2-1-3-7-12)23-18(13)21-11-20-17/h1-11H,(H,20,21,22)
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n/an/a 1.82E+4n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067329
PNG
(CHEMBL1513159)
Show SMILES Cc1ccc(cc1)-c1csc2ncnc(Nc3ccc(cc3)C(O)=O)c12
Show InChI InChI=1S/C20H15N3O2S/c1-12-2-4-13(5-3-12)16-10-26-19-17(16)18(21-11-22-19)23-15-8-6-14(7-9-15)20(24)25/h2-11H,1H3,(H,24,25)(H,21,22,23)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067331
PNG
(CHEMBL3401766)
Show SMILES CCOC(=O)c1sc2ncnc(Nc3ccc(OC)cc3)c2c1C
Show InChI InChI=1S/C17H17N3O3S/c1-4-23-17(21)14-10(2)13-15(18-9-19-16(13)24-14)20-11-5-7-12(22-3)8-6-11/h5-9H,4H2,1-3H3,(H,18,19,20)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067326
PNG
(CHEMBL3237084)
Show SMILES CCOC(=O)c1sc2ncnc(Nc3ccc(F)cc3)c2c1C
Show InChI InChI=1S/C16H14FN3O2S/c1-3-22-16(21)13-9(2)12-14(18-8-19-15(12)23-13)20-11-6-4-10(17)5-7-11/h4-8H,3H2,1-2H3,(H,18,19,20)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067325
PNG
(CHEMBL3237083)
Show SMILES Fc1ccc(Nc2ncnc3scc(-c4ccc(Cl)cc4)c23)cc1
Show InChI InChI=1S/C18H11ClFN3S/c19-12-3-1-11(2-4-12)15-9-24-18-16(15)17(21-10-22-18)23-14-7-5-13(20)6-8-14/h1-10H,(H,21,22,23)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067335
PNG
(CHEMBL3401770)
Show SMILES COc1cccc(Nc2ncnc3scc(-c4ccc(Cl)cc4)c23)c1
Show InChI InChI=1S/C19H14ClN3OS/c1-24-15-4-2-3-14(9-15)23-18-17-16(10-25-19(17)22-11-21-18)12-5-7-13(20)8-6-12/h2-11H,1H3,(H,21,22,23)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067334
PNG
(CHEMBL3401769)
Show SMILES CCOC(=O)c1sc2ncnc(Nc3cccc(OC)c3)c2c1C
Show InChI InChI=1S/C17H17N3O3S/c1-4-23-17(21)14-10(2)13-15(18-9-19-16(13)24-14)20-11-6-5-7-12(8-11)22-3/h5-9H,4H2,1-3H3,(H,18,19,20)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067328
PNG
(CHEMBL1470707)
Show SMILES CCOC(=O)c1sc2ncnc(Nc3cccc(c3)C(O)=O)c2c1C
Show InChI InChI=1S/C17H15N3O4S/c1-3-24-17(23)13-9(2)12-14(18-8-19-15(12)25-13)20-11-6-4-5-10(7-11)16(21)22/h4-8H,3H2,1-2H3,(H,21,22)(H,18,19,20)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067324
PNG
(CHEMBL3401763)
Show SMILES Cc1ccc(cc1)-c1csc2ncnc(Nc3ccc(F)cc3)c12
Show InChI InChI=1S/C19H14FN3S/c1-12-2-4-13(5-3-12)16-10-24-19-17(16)18(21-11-22-19)23-15-8-6-14(20)7-9-15/h2-11H,1H3,(H,21,22,23)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067337
PNG
(CHEMBL3401772)
Show SMILES CCOc1ccc(cc1)-c1csc2ncnc(Nc3ccc(O)cc3)c12
Show InChI InChI=1S/C20H17N3O2S/c1-2-25-16-9-3-13(4-10-16)17-11-26-20-18(17)19(21-12-22-20)23-14-5-7-15(24)8-6-14/h3-12,24H,2H2,1H3,(H,21,22,23)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50067232
PNG
(CHEMBL3401760)
Show SMILES Fc1ccccc1Nc1ncnc2scc(-c3ccccc3)c12
Show InChI InChI=1S/C18H12FN3S/c19-14-8-4-5-9-15(14)22-17-16-13(12-6-2-1-3-7-12)10-23-18(16)21-11-20-17/h1-11H,(H,20,21,22)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Institute of Molecular Biology and Genetics NAS of Ukraine

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...

Bioorg Med Chem 23: 2287-93 (2015)


Article DOI: 10.1016/j.bmc.2014.12.044
BindingDB Entry DOI: 10.7270/Q2RB7692
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%