Affinity Data by PubMed id=25996453

PubMed code 25996453

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	6.5	n/a
Jiangnan University					Assay Description Briefly, the tested compounds were solubilized in DMSO and serially diluted into concentrations for the inhibitory test. The assays were carried out ...				Chem Biol Drug Des 86: 1161-7 (2015) Article DOI: 10.1111/cbdd.12587 BindingDB Entry DOI: 10.7270/Q20C4TJ1
Jiangnan University					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM167900 (Biphenyl-4,4'-diylbis((3-phenyl-1-oxa-2,8-diaz...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.87E+3	n/a	n/a	n/a	n/a	6.5	n/a
Jiangnan University					Assay Description Briefly, the tested compounds were solubilized in DMSO and serially diluted into concentrations for the inhibitory test. The assays were carried out ...				Chem Biol Drug Des 86: 1161-7 (2015) Article DOI: 10.1111/cbdd.12587 BindingDB Entry DOI: 10.7270/Q20C4TJ1
Jiangnan University					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM167901 (Biphenyl-4,4'-diylbis((3-(2-fluorophenyl)-1-ox...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.96E+3	n/a	n/a	n/a	n/a	6.5	n/a
Jiangnan University					Assay Description Briefly, the tested compounds were solubilized in DMSO and serially diluted into concentrations for the inhibitory test. The assays were carried out ...				Chem Biol Drug Des 86: 1161-7 (2015) Article DOI: 10.1111/cbdd.12587 BindingDB Entry DOI: 10.7270/Q20C4TJ1
Jiangnan University					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM167902 (Biphenyl-4,4'-diylbis((3-(3-fluorophenyl)-1-ox...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.33E+3	n/a	n/a	n/a	n/a	6.5	n/a
Jiangnan University					Assay Description Briefly, the tested compounds were solubilized in DMSO and serially diluted into concentrations for the inhibitory test. The assays were carried out ...				Chem Biol Drug Des 86: 1161-7 (2015) Article DOI: 10.1111/cbdd.12587 BindingDB Entry DOI: 10.7270/Q20C4TJ1
Jiangnan University					More data for this Ligand-Target Pair

* indicates data uncertainty>20%