Found 92 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106579
(CHEMBL3601036)Show SMILES OC1CCN(Cc2ccc(NCCCc3ccc(OCc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C26H32N4O2/c31-25-14-17-30(18-15-25)19-21-8-10-23(11-9-21)27-16-4-7-24-12-13-26(29-28-24)32-20-22-5-2-1-3-6-22/h1-3,5-6,8-13,25,27,31H,4,7,14-20H2 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106487
(CHEMBL3600970)Show SMILES Clc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C27H31ClN2/c28-26-14-12-25(13-15-26)24-10-6-22(7-11-24)5-4-18-29-27-16-8-23(9-17-27)21-30-19-2-1-3-20-30/h6-17,29H,1-5,18-21H2 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106583
(CHEMBL3601040)Show SMILES OCC1CCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(Cl)cc3)cc2)CC1 Show InChI InChI=1S/C26H30ClN3O2/c27-23-7-5-22(6-8-23)26-12-9-24(28-29-26)2-1-17-32-25-10-3-20(4-11-25)18-30-15-13-21(19-31)14-16-30/h3-12,21,31H,1-2,13-19H2 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106522
(CHEMBL3600978)Show SMILES Clc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)nn1 Show InChI InChI=1S/C25H29ClN4/c26-22-10-8-21(9-11-22)25-15-14-24(28-29-25)5-4-16-27-23-12-6-20(7-13-23)19-30-17-2-1-3-18-30/h6-15,27H,1-5,16-19H2 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106529
(CHEMBL3601033)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCC(O)C3)cc2)nn1 Show InChI InChI=1S/C26H32N4O2/c1-32-25-13-8-21(9-14-25)26-15-12-23(28-29-26)4-2-16-27-22-10-6-20(7-11-22)18-30-17-3-5-24(31)19-30/h6-15,24,27,31H,2-5,16-19H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106520
(CHEMBL3600980)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)nn1 Show InChI InChI=1S/C26H32N4O/c1-31-25-14-9-22(10-15-25)26-16-13-24(28-29-26)6-5-17-27-23-11-7-21(8-12-23)20-30-18-3-2-4-19-30/h7-16,27H,2-6,17-20H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106523
(CHEMBL3601038)Show SMILES CC(=O)NC1CCN(Cc2ccc(NCCCc3ccc(Oc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C27H33N5O2/c1-21(33)29-24-15-18-32(19-16-24)20-22-9-11-23(12-10-22)28-17-5-6-25-13-14-27(31-30-25)34-26-7-3-2-4-8-26/h2-4,7-14,24,28H,5-6,15-20H2,1H3,(H,29,33) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106603
(CHEMBL3601047)Show SMILES CC(=O)NC1CCN(Cc2ccc(OCCCc3ccc(Oc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C27H32N4O3/c1-21(32)28-23-15-17-31(18-16-23)20-22-9-12-25(13-10-22)33-19-5-6-24-11-14-27(30-29-24)34-26-7-3-2-4-8-26/h2-4,7-14,23H,5-6,15-20H2,1H3,(H,28,32) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106489
(CHEMBL3600971)Show SMILES Clc1ccc(cc1)-c1ccc(cc1)C#CC(=O)Nc1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C27H25ClN2O/c28-25-13-11-24(12-14-25)23-9-4-21(5-10-23)8-17-27(31)29-26-15-6-22(7-16-26)20-30-18-2-1-3-19-30/h4-7,9-16H,1-3,18-20H2,(H,29,31) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106544
(CHEMBL3601035)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCC(CC3)NC(C)=O)cc2)nn1 Show InChI InChI=1S/C28H35N5O2/c1-21(34)30-25-15-18-33(19-16-25)20-22-5-9-24(10-6-22)29-17-3-4-26-11-14-28(32-31-26)23-7-12-27(35-2)13-8-23/h5-14,25,29H,3-4,15-20H2,1-2H3,(H,30,34) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106586
(CHEMBL3601043)Show SMILES OCC1CCN(Cc2ccc(OCCCc3ccc(Oc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C26H31N3O3/c30-20-22-14-16-29(17-15-22)19-21-8-11-24(12-9-21)31-18-4-5-23-10-13-26(28-27-23)32-25-6-2-1-3-7-25/h1-3,6-13,22,30H,4-5,14-20H2 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106585
(CHEMBL3601042)Show SMILES OC1CCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(Cl)cc3)cc2)CC1 Show InChI InChI=1S/C25H28ClN3O2/c26-21-7-5-20(6-8-21)25-12-9-22(27-28-25)2-1-17-31-24-10-3-19(4-11-24)18-29-15-13-23(30)14-16-29/h3-12,23,30H,1-2,13-18H2 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106601
(CHEMBL3601045)Show SMILES CC(=O)NC1CCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(F)cc3)cc2)CC1 Show InChI InChI=1S/C27H31FN4O2/c1-20(33)29-24-14-16-32(17-15-24)19-21-4-11-26(12-5-21)34-18-2-3-25-10-13-27(31-30-25)22-6-8-23(28)9-7-22/h4-13,24H,2-3,14-19H2,1H3,(H,29,33) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106582
(CHEMBL3601039)Show SMILES O[C@@H]1CCCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(Cl)cc3)cc2)C1 |r| Show InChI InChI=1S/C25H28ClN3O2/c26-21-9-7-20(8-10-21)25-14-11-22(27-28-25)3-2-16-31-24-12-5-19(6-13-24)17-29-15-1-4-23(30)18-29/h5-14,23,30H,1-4,15-18H2/t23-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106430
(CHEMBL3600972)Show SMILES Clc1ccc(cc1)-c1ccc(\C=C\C(=O)Nc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C27H27ClN2O/c28-25-13-11-24(12-14-25)23-9-4-21(5-10-23)8-17-27(31)29-26-15-6-22(7-16-26)20-30-18-2-1-3-19-30/h4-17H,1-3,18-20H2,(H,29,31)/b17-8+ | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106429
(CHEMBL3600973)Show SMILES CN(CCCc1ccc(cc1)-c1ccc(Cl)cc1)c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C28H33ClN2/c1-30(28-17-9-24(10-18-28)22-31-20-3-2-4-21-31)19-5-6-23-7-11-25(12-8-23)26-13-15-27(29)16-14-26/h7-18H,2-6,19-22H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106530
(CHEMBL3601034)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCC(O)CC3)cc2)nn1 Show InChI InChI=1S/C26H32N4O2/c1-32-25-11-6-21(7-12-25)26-13-10-23(28-29-26)3-2-16-27-22-8-4-20(5-9-22)19-30-17-14-24(31)15-18-30/h4-13,24,27,31H,2-3,14-19H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106528
(CHEMBL3601032)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCOCC3)cc2)nn1 Show InChI InChI=1S/C25H30N4O2/c1-30-24-11-6-21(7-12-24)25-13-10-23(27-28-25)3-2-14-26-22-8-4-20(5-9-22)19-29-15-17-31-18-16-29/h4-13,26H,2-3,14-19H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106521
(CHEMBL3600979)Show SMILES Fc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)nn1 Show InChI InChI=1S/C25H29FN4/c26-22-10-8-21(9-11-22)25-15-14-24(28-29-25)5-4-16-27-23-12-6-20(7-13-23)19-30-17-2-1-3-18-30/h6-15,27H,1-5,16-19H2 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106602
(CHEMBL3601046)Show SMILES CC(=O)NC1CCN(Cc2ccc(OCCCc3ccc(Cc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C28H34N4O2/c1-22(33)29-25-15-17-32(18-16-25)21-24-9-13-28(14-10-24)34-19-5-8-26-11-12-27(31-30-26)20-23-6-3-2-4-7-23/h2-4,6-7,9-14,25H,5,8,15-21H2,1H3,(H,29,33) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106524
(CHEMBL3601037)Show SMILES OC1CCN(Cc2ccc(NCCCc3ccc(Oc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C25H30N4O2/c30-23-14-17-29(18-15-23)19-20-8-10-21(11-9-20)26-16-4-5-22-12-13-25(28-27-22)31-24-6-2-1-3-7-24/h1-3,6-13,23,26,30H,4-5,14-19H2 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106425
(CHEMBL3600977)Show SMILES Clc1ccc(cc1)-c1ccc(CNC(=O)Nc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C26H28ClN3O/c27-24-12-10-23(11-13-24)22-8-4-20(5-9-22)18-28-26(31)29-25-14-6-21(7-15-25)19-30-16-2-1-3-17-30/h4-15H,1-3,16-19H2,(H2,28,29,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106521
(CHEMBL3600979)Show SMILES Fc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)nn1 Show InChI InChI=1S/C25H29FN4/c26-22-10-8-21(9-11-22)25-15-14-24(28-29-25)5-4-16-27-23-12-6-20(7-13-23)19-30-17-2-1-3-18-30/h6-15,27H,1-5,16-19H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106428
(CHEMBL3600974)Show SMILES Clc1ccc(cc1)-c1ccc(CCC(=O)Nc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C27H29ClN2O/c28-25-13-11-24(12-14-25)23-9-4-21(5-10-23)8-17-27(31)29-26-15-6-22(7-16-26)20-30-18-2-1-3-19-30/h4-7,9-16H,1-3,8,17-20H2,(H,29,31) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106428
(CHEMBL3600974)Show SMILES Clc1ccc(cc1)-c1ccc(CCC(=O)Nc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C27H29ClN2O/c28-25-13-11-24(12-14-25)23-9-4-21(5-10-23)8-17-27(31)29-26-15-6-22(7-16-26)20-30-18-2-1-3-19-30/h4-7,9-16H,1-3,8,17-20H2,(H,29,31) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106427
(CHEMBL3600975)Show SMILES Clc1ccc(cc1)-c1ccc(OCC(=O)Nc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C26H27ClN2O2/c27-23-10-6-21(7-11-23)22-8-14-25(15-9-22)31-19-26(30)28-24-12-4-20(5-13-24)18-29-16-2-1-3-17-29/h4-15H,1-3,16-19H2,(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106584
(CHEMBL3601041)Show SMILES O[C@@H]1CCCN(Cc2ccc(OCCCc3ccc(Oc4ccccc4)nn3)cc2)C1 |r| Show InChI InChI=1S/C25H29N3O3/c29-22-7-4-16-28(19-22)18-20-10-13-23(14-11-20)30-17-5-6-21-12-15-25(27-26-21)31-24-8-2-1-3-9-24/h1-3,8-15,22,29H,4-7,16-19H2/t22-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106427
(CHEMBL3600975)Show SMILES Clc1ccc(cc1)-c1ccc(OCC(=O)Nc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C26H27ClN2O2/c27-23-10-6-21(7-11-23)22-8-14-25(15-9-22)31-19-26(30)28-24-12-4-20(5-13-24)18-29-16-2-1-3-17-29/h4-15H,1-3,16-19H2,(H,28,30) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106526
(CHEMBL3601030)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCC3)cc2)nn1 Show InChI InChI=1S/C25H30N4O/c1-30-24-13-8-21(9-14-24)25-15-12-23(27-28-25)5-4-16-26-22-10-6-20(7-11-22)19-29-17-2-3-18-29/h6-15,26H,2-5,16-19H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106522
(CHEMBL3600978)Show SMILES Clc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)nn1 Show InChI InChI=1S/C25H29ClN4/c26-22-10-8-21(9-11-22)25-15-14-24(28-29-25)5-4-16-27-23-12-6-20(7-13-23)19-30-17-2-1-3-18-30/h6-15,27H,1-5,16-19H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 138 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106428
(CHEMBL3600974)Show SMILES Clc1ccc(cc1)-c1ccc(CCC(=O)Nc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C27H29ClN2O/c28-25-13-11-24(12-14-25)23-9-4-21(5-10-23)8-17-27(31)29-26-15-6-22(7-16-26)20-30-18-2-1-3-19-30/h4-7,9-16H,1-3,8,17-20H2,(H,29,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 138 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106525
(CHEMBL3600981)Show SMILES N#Cc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)nn1 Show InChI InChI=1S/C26H29N5/c27-19-21-6-10-23(11-7-21)26-15-14-25(29-30-26)5-4-16-28-24-12-8-22(9-13-24)20-31-17-2-1-3-18-31/h6-15,28H,1-5,16-18,20H2 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 151 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106527
(CHEMBL3601031)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN(C)C)cc2)nn1 Show InChI InChI=1S/C23H28N4O/c1-27(2)17-18-6-10-20(11-7-18)24-16-4-5-21-12-15-23(26-25-21)19-8-13-22(28-3)14-9-19/h6-15,24H,4-5,16-17H2,1-3H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 154 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106600
(CHEMBL3601044)Show SMILES OC1CCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(F)cc3)cc2)CC1 Show InChI InChI=1S/C25H28FN3O2/c26-21-7-5-20(6-8-21)25-12-9-22(27-28-25)2-1-17-31-24-10-3-19(4-11-24)18-29-15-13-23(30)14-16-29/h3-12,23,30H,1-2,13-18H2 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 186 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106489
(CHEMBL3600971)Show SMILES Clc1ccc(cc1)-c1ccc(cc1)C#CC(=O)Nc1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C27H25ClN2O/c28-25-13-11-24(12-14-25)23-9-4-21(5-10-23)8-17-27(31)29-26-15-6-22(7-16-26)20-30-18-2-1-3-19-30/h4-7,9-16H,1-3,18-20H2,(H,29,31) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 225 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106600
(CHEMBL3601044)Show SMILES OC1CCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(F)cc3)cc2)CC1 Show InChI InChI=1S/C25H28FN3O2/c26-21-7-5-20(6-8-21)25-12-9-22(27-28-25)2-1-17-31-24-10-3-19(4-11-24)18-29-15-13-23(30)14-16-29/h3-12,23,30H,1-2,13-18H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 242 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106522
(CHEMBL3600978)Show SMILES Clc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)nn1 Show InChI InChI=1S/C25H29ClN4/c26-22-10-8-21(9-11-22)25-15-14-24(28-29-25)5-4-16-27-23-12-6-20(7-13-23)19-30-17-2-1-3-18-30/h6-15,27H,1-5,16-19H2 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106487
(CHEMBL3600970)Show SMILES Clc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C27H31ClN2/c28-26-14-12-25(13-15-26)24-10-6-22(7-11-24)5-4-18-29-27-16-8-23(9-17-27)21-30-19-2-1-3-20-30/h6-17,29H,1-5,18-21H2 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 325 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106426
(CHEMBL3600976)Show SMILES CN(C(=O)\C=C\c1ccc(cc1)-c1ccc(Cl)cc1)c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C28H29ClN2O/c1-30(27-16-7-23(8-17-27)21-31-19-3-2-4-20-31)28(32)18-9-22-5-10-24(11-6-22)25-12-14-26(29)15-13-25/h5-18H,2-4,19-21H2,1H3/b18-9+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 362 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106430
(CHEMBL3600972)Show SMILES Clc1ccc(cc1)-c1ccc(\C=C\C(=O)Nc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C27H27ClN2O/c28-25-13-11-24(12-14-25)23-9-4-21(5-10-23)8-17-27(31)29-26-15-6-22(7-16-26)20-30-18-2-1-3-19-30/h4-17H,1-3,18-20H2,(H,29,31)/b17-8+ | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 401 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106429
(CHEMBL3600973)Show SMILES CN(CCCc1ccc(cc1)-c1ccc(Cl)cc1)c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C28H33ClN2/c1-30(28-17-9-24(10-18-28)22-31-20-3-2-4-21-31)19-5-6-23-7-11-25(12-8-23)26-13-15-27(29)16-14-26/h7-18H,2-6,19-22H2,1H3 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 419 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106427
(CHEMBL3600975)Show SMILES Clc1ccc(cc1)-c1ccc(OCC(=O)Nc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C26H27ClN2O2/c27-23-10-6-21(7-11-23)22-8-14-25(15-9-22)31-19-26(30)28-24-12-4-20(5-13-24)18-29-16-2-1-3-17-29/h4-15H,1-3,16-19H2,(H,28,30) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 446 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106425
(CHEMBL3600977)Show SMILES Clc1ccc(cc1)-c1ccc(CNC(=O)Nc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C26H28ClN3O/c27-24-12-10-23(11-13-24)22-8-4-20(5-9-22)18-28-26(31)29-25-14-6-21(7-15-25)19-30-16-2-1-3-17-30/h4-15H,1-3,16-19H2,(H2,28,29,31) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 511 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106582
(CHEMBL3601039)Show SMILES O[C@@H]1CCCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(Cl)cc3)cc2)C1 |r| Show InChI InChI=1S/C25H28ClN3O2/c26-21-9-7-20(8-10-21)25-14-11-22(27-28-25)3-2-16-31-24-12-5-19(6-13-24)17-29-15-1-4-23(30)18-29/h5-14,23,30H,1-4,15-18H2/t23-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 595 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106426
(CHEMBL3600976)Show SMILES CN(C(=O)\C=C\c1ccc(cc1)-c1ccc(Cl)cc1)c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C28H29ClN2O/c1-30(27-16-7-23(8-17-27)21-31-19-3-2-4-20-31)28(32)18-9-22-5-10-24(11-6-22)25-12-14-26(29)15-13-25/h5-18H,2-4,19-21H2,1H3/b18-9+ | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 625 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106426
(CHEMBL3600976)Show SMILES CN(C(=O)\C=C\c1ccc(cc1)-c1ccc(Cl)cc1)c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C28H29ClN2O/c1-30(27-16-7-23(8-17-27)21-31-19-3-2-4-20-31)28(32)18-9-22-5-10-24(11-6-22)25-12-14-26(29)15-13-25/h5-18H,2-4,19-21H2,1H3/b18-9+ | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 634 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106429
(CHEMBL3600973)Show SMILES CN(CCCc1ccc(cc1)-c1ccc(Cl)cc1)c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C28H33ClN2/c1-30(28-17-9-24(10-18-28)22-31-20-3-2-4-21-31)19-5-6-23-7-11-25(12-8-23)26-13-15-27(29)16-14-26/h7-18H,2-6,19-22H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 646 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106487
(CHEMBL3600970)Show SMILES Clc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C27H31ClN2/c28-26-14-12-25(13-15-26)24-10-6-22(7-11-24)5-4-18-29-27-16-8-23(9-17-27)21-30-19-2-1-3-20-30/h6-17,29H,1-5,18-21H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106601
(CHEMBL3601045)Show SMILES CC(=O)NC1CCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(F)cc3)cc2)CC1 Show InChI InChI=1S/C27H31FN4O2/c1-20(33)29-24-14-16-32(17-15-24)19-21-4-11-26(12-5-21)34-18-2-3-25-10-13-27(31-30-25)22-6-8-23(28)9-7-22/h4-13,24H,2-3,14-19H2,1H3,(H,29,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 713 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106583
(CHEMBL3601040)Show SMILES OCC1CCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(Cl)cc3)cc2)CC1 Show InChI InChI=1S/C26H30ClN3O2/c27-23-7-5-22(6-8-23)26-12-9-24(28-29-26)2-1-17-32-25-10-3-20(4-11-25)18-30-15-13-21(19-31)14-16-30/h3-12,21,31H,1-2,13-19H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106425
(CHEMBL3600977)Show SMILES Clc1ccc(cc1)-c1ccc(CNC(=O)Nc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C26H28ClN3O/c27-24-12-10-23(11-13-24)22-8-4-20(5-9-22)18-28-26(31)29-25-14-6-21(7-15-25)19-30-16-2-1-3-17-30/h4-15H,1-3,16-19H2,(H2,28,29,31) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 899 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106520
(CHEMBL3600980)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)nn1 Show InChI InChI=1S/C26H32N4O/c1-31-25-14-9-22(10-15-25)26-16-13-24(28-29-26)6-5-17-27-23-11-7-21(8-12-23)20-30-18-3-2-4-19-30/h7-16,27H,2-6,17-20H2,1H3 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 962 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106527
(CHEMBL3601031)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN(C)C)cc2)nn1 Show InChI InChI=1S/C23H28N4O/c1-27(2)17-18-6-10-20(11-7-18)24-16-4-5-21-12-15-23(26-25-21)19-8-13-22(28-3)14-9-19/h6-15,24H,4-5,16-17H2,1-3H3 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106585
(CHEMBL3601042)Show SMILES OC1CCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(Cl)cc3)cc2)CC1 Show InChI InChI=1S/C25H28ClN3O2/c26-21-7-5-20(6-8-21)25-12-9-22(27-28-25)2-1-17-31-24-10-3-19(4-11-24)18-29-15-13-23(30)14-16-29/h3-12,23,30H,1-2,13-18H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106525
(CHEMBL3600981)Show SMILES N#Cc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)nn1 Show InChI InChI=1S/C26H29N5/c27-19-21-6-10-23(11-7-21)26-15-14-25(29-30-26)5-4-16-28-24-12-8-22(9-13-24)20-31-17-2-1-3-18-31/h6-15,28H,1-5,16-18,20H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106583
(CHEMBL3601040)Show SMILES OCC1CCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(Cl)cc3)cc2)CC1 Show InChI InChI=1S/C26H30ClN3O2/c27-23-7-5-22(6-8-23)26-12-9-24(28-29-26)2-1-17-32-25-10-3-20(4-11-25)18-30-15-13-21(19-31)14-16-30/h3-12,21,31H,1-2,13-19H2 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106520
(CHEMBL3600980)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)nn1 Show InChI InChI=1S/C26H32N4O/c1-31-25-14-9-22(10-15-25)26-16-13-24(28-29-26)6-5-17-27-23-11-7-21(8-12-23)20-30-18-3-2-4-19-30/h7-16,27H,2-6,17-20H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106526
(CHEMBL3601030)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCC3)cc2)nn1 Show InChI InChI=1S/C25H30N4O/c1-30-24-13-8-21(9-14-24)25-15-12-23(27-28-25)5-4-16-26-22-10-6-20(7-11-22)19-29-17-2-3-18-29/h6-15,26H,2-5,16-19H2,1H3 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106525
(CHEMBL3600981)Show SMILES N#Cc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)nn1 Show InChI InChI=1S/C26H29N5/c27-19-21-6-10-23(11-7-21)26-15-14-25(29-30-26)5-4-16-28-24-12-8-22(9-13-24)20-31-17-2-1-3-18-31/h6-15,28H,1-5,16-18,20H2 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106430
(CHEMBL3600972)Show SMILES Clc1ccc(cc1)-c1ccc(\C=C\C(=O)Nc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C27H27ClN2O/c28-25-13-11-24(12-14-25)23-9-4-21(5-10-23)8-17-27(31)29-26-15-6-22(7-16-26)20-30-18-2-1-3-19-30/h4-17H,1-3,18-20H2,(H,29,31)/b17-8+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 1.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106586
(CHEMBL3601043)Show SMILES OCC1CCN(Cc2ccc(OCCCc3ccc(Oc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C26H31N3O3/c30-20-22-14-16-29(17-15-22)19-21-8-11-24(12-9-21)31-18-4-5-23-10-13-26(28-27-23)32-25-6-2-1-3-7-25/h1-3,6-13,22,30H,4-5,14-20H2 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106581
(CHEMBL3600982)Show SMILES C(CNc1ccc(CN2CCCCC2)cc1)Cc1ccc(nn1)-c1ccncc1 Show InChI InChI=1S/C24H29N5/c1-2-17-29(18-3-1)19-20-6-8-22(9-7-20)26-14-4-5-23-10-11-24(28-27-23)21-12-15-25-16-13-21/h6-13,15-16,26H,1-5,14,17-19H2 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50106580
(CHEMBL3601029)Show InChI InChI=1S/C20H28N4O/c1-25-20-12-11-19(22-23-20)6-5-13-21-18-9-7-17(8-10-18)16-24-14-3-2-4-15-24/h7-12,21H,2-6,13-16H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106521
(CHEMBL3600979)Show SMILES Fc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)nn1 Show InChI InChI=1S/C25H29FN4/c26-22-10-8-21(9-11-22)25-15-14-24(28-29-25)5-4-16-27-23-12-6-20(7-13-23)19-30-17-2-1-3-18-30/h6-15,27H,1-5,16-19H2 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106601
(CHEMBL3601045)Show SMILES CC(=O)NC1CCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(F)cc3)cc2)CC1 Show InChI InChI=1S/C27H31FN4O2/c1-20(33)29-24-14-16-32(17-15-24)19-21-4-11-26(12-5-21)34-18-2-3-25-10-13-27(31-30-25)22-6-8-23(28)9-7-22/h4-13,24H,2-3,14-19H2,1H3,(H,29,33) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106526
(CHEMBL3601030)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCC3)cc2)nn1 Show InChI InChI=1S/C25H30N4O/c1-30-24-13-8-21(9-14-24)25-15-12-23(27-28-25)5-4-16-26-22-10-6-20(7-11-22)19-29-17-2-3-18-29/h6-15,26H,2-5,16-19H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106527
(CHEMBL3601031)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN(C)C)cc2)nn1 Show InChI InChI=1S/C23H28N4O/c1-27(2)17-18-6-10-20(11-7-18)24-16-4-5-21-12-15-23(26-25-21)19-8-13-22(28-3)14-9-19/h6-15,24H,4-5,16-17H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106582
(CHEMBL3601039)Show SMILES O[C@@H]1CCCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(Cl)cc3)cc2)C1 |r| Show InChI InChI=1S/C25H28ClN3O2/c26-21-9-7-20(8-10-21)25-14-11-22(27-28-25)3-2-16-31-24-12-5-19(6-13-24)17-29-15-1-4-23(30)18-29/h5-14,23,30H,1-4,15-18H2/t23-/m1/s1 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106530
(CHEMBL3601034)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCC(O)CC3)cc2)nn1 Show InChI InChI=1S/C26H32N4O2/c1-32-25-11-6-21(7-12-25)26-13-10-23(28-29-26)3-2-16-27-22-8-4-20(5-9-22)19-30-17-14-24(31)15-18-30/h4-13,24,27,31H,2-3,14-19H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106603
(CHEMBL3601047)Show SMILES CC(=O)NC1CCN(Cc2ccc(OCCCc3ccc(Oc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C27H32N4O3/c1-21(32)28-23-15-17-31(18-16-23)20-22-9-12-25(13-10-22)33-19-5-6-24-11-14-27(30-29-24)34-26-7-3-2-4-8-26/h2-4,7-14,23H,5-6,15-20H2,1H3,(H,28,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106600
(CHEMBL3601044)Show SMILES OC1CCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(F)cc3)cc2)CC1 Show InChI InChI=1S/C25H28FN3O2/c26-21-7-5-20(6-8-21)25-12-9-22(27-28-25)2-1-17-31-24-10-3-19(4-11-24)18-29-15-13-23(30)14-16-29/h3-12,23,30H,1-2,13-18H2 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50106523
(CHEMBL3601038)Show SMILES CC(=O)NC1CCN(Cc2ccc(NCCCc3ccc(Oc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C27H33N5O2/c1-21(33)29-24-15-18-32(19-16-24)20-22-9-11-23(12-10-22)28-17-5-6-25-13-14-27(31-30-25)34-26-7-3-2-4-8-26/h2-4,7-14,24,28H,5-6,15-20H2,1H3,(H,29,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Inhibition of human ERG by patch clamp assay |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106579
(CHEMBL3601036)Show SMILES OC1CCN(Cc2ccc(NCCCc3ccc(OCc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C26H32N4O2/c31-25-14-17-30(18-15-25)19-21-8-10-23(11-9-21)27-16-4-7-24-12-13-26(29-28-24)32-20-22-5-2-1-3-6-22/h1-3,5-6,8-13,25,27,31H,4,7,14-20H2 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106585
(CHEMBL3601042)Show SMILES OC1CCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(Cl)cc3)cc2)CC1 Show InChI InChI=1S/C25H28ClN3O2/c26-21-7-5-20(6-8-21)25-12-9-22(27-28-25)2-1-17-31-24-10-3-19(4-11-24)18-29-15-13-23(30)14-16-29/h3-12,23,30H,1-2,13-18H2 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106579
(CHEMBL3601036)Show SMILES OC1CCN(Cc2ccc(NCCCc3ccc(OCc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C26H32N4O2/c31-25-14-17-30(18-15-25)19-21-8-10-23(11-9-21)27-16-4-7-24-12-13-26(29-28-24)32-20-22-5-2-1-3-6-22/h1-3,5-6,8-13,25,27,31H,4,7,14-20H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106523
(CHEMBL3601038)Show SMILES CC(=O)NC1CCN(Cc2ccc(NCCCc3ccc(Oc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C27H33N5O2/c1-21(33)29-24-15-18-32(19-16-24)20-22-9-11-23(12-10-22)28-17-5-6-25-13-14-27(31-30-25)34-26-7-3-2-4-8-26/h2-4,7-14,24,28H,5-6,15-20H2,1H3,(H,29,33) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106524
(CHEMBL3601037)Show SMILES OC1CCN(Cc2ccc(NCCCc3ccc(Oc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C25H30N4O2/c30-23-14-17-29(18-15-23)19-20-8-10-21(11-9-20)26-16-4-5-22-12-13-25(28-27-22)31-24-6-2-1-3-7-24/h1-3,6-13,23,26,30H,4-5,14-19H2 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106523
(CHEMBL3601038)Show SMILES CC(=O)NC1CCN(Cc2ccc(NCCCc3ccc(Oc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C27H33N5O2/c1-21(33)29-24-15-18-32(19-16-24)20-22-9-11-23(12-10-22)28-17-5-6-25-13-14-27(31-30-25)34-26-7-3-2-4-8-26/h2-4,7-14,24,28H,5-6,15-20H2,1H3,(H,29,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106584
(CHEMBL3601041)Show SMILES O[C@@H]1CCCN(Cc2ccc(OCCCc3ccc(Oc4ccccc4)nn3)cc2)C1 |r| Show InChI InChI=1S/C25H29N3O3/c29-22-7-4-16-28(19-22)18-20-10-13-23(14-11-20)30-17-5-6-21-12-15-25(27-26-21)31-24-8-2-1-3-9-24/h1-3,8-15,22,29H,4-7,16-19H2/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106602
(CHEMBL3601046)Show SMILES CC(=O)NC1CCN(Cc2ccc(OCCCc3ccc(Cc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C28H34N4O2/c1-22(33)29-25-15-17-32(18-16-25)21-24-9-13-28(14-10-24)34-19-5-8-26-11-12-27(31-30-26)20-23-6-3-2-4-7-23/h2-4,6-7,9-14,25H,5,8,15-21H2,1H3,(H,29,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106544
(CHEMBL3601035)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCC(CC3)NC(C)=O)cc2)nn1 Show InChI InChI=1S/C28H35N5O2/c1-21(34)30-25-15-18-33(19-16-25)20-22-5-9-24(10-6-22)29-17-3-4-26-11-14-28(32-31-26)23-7-12-27(35-2)13-8-23/h5-14,25,29H,3-4,15-20H2,1-2H3,(H,30,34) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106530
(CHEMBL3601034)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCC(O)CC3)cc2)nn1 Show InChI InChI=1S/C26H32N4O2/c1-32-25-11-6-21(7-12-25)26-13-10-23(28-29-26)3-2-16-27-22-8-4-20(5-9-22)19-30-17-14-24(31)15-18-30/h4-13,24,27,31H,2-3,14-19H2,1H3 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106584
(CHEMBL3601041)Show SMILES O[C@@H]1CCCN(Cc2ccc(OCCCc3ccc(Oc4ccccc4)nn3)cc2)C1 |r| Show InChI InChI=1S/C25H29N3O3/c29-22-7-4-16-28(19-22)18-20-10-13-23(14-11-20)30-17-5-6-21-12-15-25(27-26-21)31-24-8-2-1-3-9-24/h1-3,8-15,22,29H,4-7,16-19H2/t22-/m1/s1 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106586
(CHEMBL3601043)Show SMILES OCC1CCN(Cc2ccc(OCCCc3ccc(Oc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C26H31N3O3/c30-20-22-14-16-29(17-15-22)19-21-8-11-24(12-9-21)31-18-4-5-23-10-13-26(28-27-23)32-25-6-2-1-3-7-25/h1-3,6-13,22,30H,4-5,14-20H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106529
(CHEMBL3601033)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCC(O)C3)cc2)nn1 Show InChI InChI=1S/C26H32N4O2/c1-32-25-13-8-21(9-14-25)26-15-12-23(28-29-26)4-2-16-27-22-10-6-20(7-11-22)18-30-17-3-5-24(31)19-30/h6-15,24,27,31H,2-5,16-19H2,1H3 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106529
(CHEMBL3601033)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCC(O)C3)cc2)nn1 Show InChI InChI=1S/C26H32N4O2/c1-32-25-13-8-21(9-14-25)26-15-12-23(28-29-26)4-2-16-27-22-10-6-20(7-11-22)18-30-17-3-5-24(31)19-30/h6-15,24,27,31H,2-5,16-19H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106544
(CHEMBL3601035)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCC(CC3)NC(C)=O)cc2)nn1 Show InChI InChI=1S/C28H35N5O2/c1-21(34)30-25-15-18-33(19-16-25)20-22-5-9-24(10-6-22)29-17-3-4-26-11-14-28(32-31-26)23-7-12-27(35-2)13-8-23/h5-14,25,29H,3-4,15-20H2,1-2H3,(H,30,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106524
(CHEMBL3601037)Show SMILES OC1CCN(Cc2ccc(NCCCc3ccc(Oc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C25H30N4O2/c30-23-14-17-29(18-15-23)19-20-8-10-21(11-9-20)26-16-4-5-22-12-13-25(28-27-22)31-24-6-2-1-3-7-24/h1-3,6-13,23,26,30H,4-5,14-19H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106528
(CHEMBL3601032)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCOCC3)cc2)nn1 Show InChI InChI=1S/C25H30N4O2/c1-30-24-11-6-21(7-12-24)25-13-10-23(27-28-25)3-2-14-26-22-8-4-20(5-9-22)19-29-15-17-31-18-16-29/h4-13,26H,2-3,14-19H2,1H3 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50106528
(CHEMBL3601032)Show SMILES COc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCOCC3)cc2)nn1 Show InChI InChI=1S/C25H30N4O2/c1-30-24-11-6-21(7-12-24)25-13-10-23(27-28-25)3-2-14-26-22-8-4-20(5-9-22)19-29-15-17-31-18-16-29/h4-13,26H,2-3,14-19H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106603
(CHEMBL3601047)Show SMILES CC(=O)NC1CCN(Cc2ccc(OCCCc3ccc(Oc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C27H32N4O3/c1-21(32)28-23-15-17-31(18-16-23)20-22-9-12-25(13-10-22)33-19-5-6-24-11-14-27(30-29-24)34-26-7-3-2-4-8-26/h2-4,7-14,23H,5-6,15-20H2,1H3,(H,28,32) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50106602
(CHEMBL3601046)Show SMILES CC(=O)NC1CCN(Cc2ccc(OCCCc3ccc(Cc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C28H34N4O2/c1-22(33)29-25-15-17-32(18-16-25)21-24-9-13-28(14-10-24)34-19-5-8-26-11-12-27(31-30-26)20-23-6-3-2-4-7-23/h2-4,6-7,9-14,25H,5,8,15-21H2,1H3,(H,29,33) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic M1 receptor (unknown origin) |
Bioorg Med Chem Lett 25: 3270-4 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.074
BindingDB Entry DOI: 10.7270/Q2MK6FN7 |
More data for this
Ligand-Target Pair | |
Search and Browse
