Affinity Data by PubMed id=26189013

PubMed code 26189013

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM15613 (4-chloro-N-(2-morpholin-4-ylethyl)benzamide \| 4-ch...) Show SMILES Clc1ccc(cc1)C(=O)NCCN1CCOCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM152637 ((2E)-1-(4-methoxyphenyl)-3-[4-(trifluoromethyl)phe...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM152635 ((2E)-3-(4-fluorophenyl)-1-(4-methoxyphenyl)prop-2-...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccc(F)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM152633 ((2E)-3-(2-fluorophenyl)-1-(4-methoxyphenyl)prop-2-...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccccc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM152634 ((2E)-3-(3-fluorophenyl)-1-(4-methoxyphenyl)prop-2-...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1cccc(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM15579 (CHEMBL972 \| DEPRENYL \| L-Deprenyl \| N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM152636 ((2E)-1-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phe...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccccc1C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM152636 ((2E)-1-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phe...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccccc1C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM15613 (4-chloro-N-(2-morpholin-4-ylethyl)benzamide \| 4-ch...) Show SMILES Clc1ccc(cc1)C(=O)NCCN1CCOCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents	Article PubMed	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM152634 ((2E)-3-(3-fluorophenyl)-1-(4-methoxyphenyl)prop-2-...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1cccc(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM152633 ((2E)-3-(2-fluorophenyl)-1-(4-methoxyphenyl)prop-2-...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccccc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.34E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM152635 ((2E)-3-(4-fluorophenyl)-1-(4-methoxyphenyl)prop-2-...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccc(F)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM152637 ((2E)-1-(4-methoxyphenyl)-3-[4-(trifluoromethyl)phe...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM15579 (CHEMBL972 \| DEPRENYL \| L-Deprenyl \| N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	8.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Grace College of Pharmacy					Assay Description Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...				Bioorg Chem 62: 22-29 (2015) Article DOI: 10.1016/j.bioorg.2015.07.001 BindingDB Entry DOI: 10.7270/Q20K2795
Grace College of Pharmacy					More data for this Ligand-Target Pair

* indicates data uncertainty>20%