Affinity Data by PubMed id=26432605

PubMed code 26432605

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Mus musculus)	BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea \|...) Show SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Sookmyung Women's University Curated by ChEMBL					Assay Description Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassay				Bioorg Med Chem 23: 7069-78 (2015) Article DOI: 10.1016/j.bmc.2015.09.025 BindingDB Entry DOI: 10.7270/Q23N256M
Sookmyung Women's University Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11 (Mus musculus)	BDBM50128343 (CHEMBL3629176) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Sookmyung Women's University Curated by ChEMBL					Assay Description Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...				Bioorg Med Chem 23: 7069-78 (2015) Article DOI: 10.1016/j.bmc.2015.09.025 BindingDB Entry DOI: 10.7270/Q23N256M
Sookmyung Women's University Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11 (Mus musculus)	BDBM50128344 (CHEMBL3629177) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Sookmyung Women's University Curated by ChEMBL					Assay Description Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...				Bioorg Med Chem 23: 7069-78 (2015) Article DOI: 10.1016/j.bmc.2015.09.025 BindingDB Entry DOI: 10.7270/Q23N256M
Sookmyung Women's University Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11 (Mus musculus)	BDBM50128342 (CHEMBL3629175) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sookmyung Women's University Curated by ChEMBL					Assay Description Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...				Bioorg Med Chem 23: 7069-78 (2015) Article DOI: 10.1016/j.bmc.2015.09.025 BindingDB Entry DOI: 10.7270/Q23N256M
Sookmyung Women's University Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Mus musculus)	BDBM50128342 (CHEMBL3629175) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sookmyung Women's University Curated by ChEMBL					Assay Description Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassay				Bioorg Med Chem 23: 7069-78 (2015) Article DOI: 10.1016/j.bmc.2015.09.025 BindingDB Entry DOI: 10.7270/Q23N256M
Sookmyung Women's University Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Mus musculus)	BDBM50128343 (CHEMBL3629176) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sookmyung Women's University Curated by ChEMBL					Assay Description Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassay				Bioorg Med Chem 23: 7069-78 (2015) Article DOI: 10.1016/j.bmc.2015.09.025 BindingDB Entry DOI: 10.7270/Q23N256M
Sookmyung Women's University Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Mus musculus)	BDBM50128344 (CHEMBL3629177) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sookmyung Women's University Curated by ChEMBL					Assay Description Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassay				Bioorg Med Chem 23: 7069-78 (2015) Article DOI: 10.1016/j.bmc.2015.09.025 BindingDB Entry DOI: 10.7270/Q23N256M
Sookmyung Women's University Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11 (Mus musculus)	BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea \|...) Show SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sookmyung Women's University Curated by ChEMBL					Assay Description Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...				Bioorg Med Chem 23: 7069-78 (2015) Article DOI: 10.1016/j.bmc.2015.09.025 BindingDB Entry DOI: 10.7270/Q23N256M
Sookmyung Women's University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%