Affinity Data by PubMed id=26547232

PubMed code 26547232

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thymidine phosphorylase (Escherichia coli (Enterobacteria))	BDBM50134399 (1,7-Dihydro-pyrrolo[2,3-d]pyrimidine-2,4-dione \| 7...) Show SMILES O=c1[nH]c2[nH]ccc2c(=O)[nH]1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	7.0	n/a
University of Karachi					Assay Description TP inhibition assay was performed spectrophotometrically. The method of Bera et al. was followed with slight modifications. Reaction mixture of 200 �...				Bioorg Chem 63: 142-51 (2015) Article DOI: 10.1016/j.bioorg.2015.10.006 BindingDB Entry DOI: 10.7270/Q2C8282R
University of Karachi					More data for this Ligand-Target Pair
Thymidine phosphorylase (Escherichia coli (Enterobacteria))	BDBM50019242 (2-(3',4'-Dihydroxyphenyl)quinazolin-4(3H)-...) Show SMILES Oc1ccc(cc1O)-c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.29E+4	n/a	n/a	n/a	n/a	7.0	n/a
University of Karachi					Assay Description TP inhibition assay was performed spectrophotometrically. The method of Bera et al. was followed with slight modifications. Reaction mixture of 200 �...				Bioorg Chem 63: 142-51 (2015) Article DOI: 10.1016/j.bioorg.2015.10.006 BindingDB Entry DOI: 10.7270/Q2C8282R
University of Karachi					More data for this Ligand-Target Pair
Thymidine phosphorylase (Escherichia coli (Enterobacteria))	BDBM50019277 (2-(2',5'-Dihydroxyphenyl)quinazolin-4(3H)-...) Show SMILES Oc1ccc(O)c(c1)-c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.95E+4	n/a	n/a	n/a	n/a	7.0	n/a
University of Karachi					Assay Description TP inhibition assay was performed spectrophotometrically. The method of Bera et al. was followed with slight modifications. Reaction mixture of 200 �...				Bioorg Chem 63: 142-51 (2015) Article DOI: 10.1016/j.bioorg.2015.10.006 BindingDB Entry DOI: 10.7270/Q2C8282R
University of Karachi					More data for this Ligand-Target Pair
Thymidine phosphorylase (Escherichia coli (Enterobacteria))	BDBM50019170 (2-(3'-Hydroxy-4'-methoxyphenyl)quinazolin-...) Show SMILES COc1ccc(cc1O)-c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.69E+5	n/a	n/a	n/a	n/a	7.0	n/a
University of Karachi					Assay Description TP inhibition assay was performed spectrophotometrically. The method of Bera et al. was followed with slight modifications. Reaction mixture of 200 �...				Bioorg Chem 63: 142-51 (2015) Article DOI: 10.1016/j.bioorg.2015.10.006 BindingDB Entry DOI: 10.7270/Q2C8282R
University of Karachi					More data for this Ligand-Target Pair
Thymidine phosphorylase (Escherichia coli (Enterobacteria))	BDBM50019165 (2-(4'-Hydroxyphenyl)quinazolin-4(3H)-one (2) \|...) Show SMILES Oc1ccc(cc1)-c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.34E+5	n/a	n/a	n/a	n/a	7.0	n/a
University of Karachi					Assay Description TP inhibition assay was performed spectrophotometrically. The method of Bera et al. was followed with slight modifications. Reaction mixture of 200 �...				Bioorg Chem 63: 142-51 (2015) Article DOI: 10.1016/j.bioorg.2015.10.006 BindingDB Entry DOI: 10.7270/Q2C8282R
University of Karachi					More data for this Ligand-Target Pair
Thymidine phosphorylase (Escherichia coli (Enterobacteria))	BDBM50019203 (2-(3'-Ethoxy-4'-hydroxyphenyl)quinazolin-4...) Show SMILES CCOc1cc(ccc1O)-c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.56E+5	n/a	n/a	n/a	n/a	7.0	n/a
University of Karachi					Assay Description TP inhibition assay was performed spectrophotometrically. The method of Bera et al. was followed with slight modifications. Reaction mixture of 200 �...				Bioorg Chem 63: 142-51 (2015) Article DOI: 10.1016/j.bioorg.2015.10.006 BindingDB Entry DOI: 10.7270/Q2C8282R
University of Karachi					More data for this Ligand-Target Pair
Thymidine phosphorylase (Escherichia coli (Enterobacteria))	BDBM50019168 (2-(3'-Hydroxyphenyl)quinazolin-4(3H)-one (3) \|...) Show SMILES Oc1cccc(c1)-c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.95E+5	n/a	n/a	n/a	n/a	7.0	n/a
University of Karachi					Assay Description TP inhibition assay was performed spectrophotometrically. The method of Bera et al. was followed with slight modifications. Reaction mixture of 200 �...				Bioorg Chem 63: 142-51 (2015) Article DOI: 10.1016/j.bioorg.2015.10.006 BindingDB Entry DOI: 10.7270/Q2C8282R
University of Karachi					More data for this Ligand-Target Pair

* indicates data uncertainty>20%