Affinity Data by PubMed id=26822568

PubMed code 26822568

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Leucine--tRNA ligase, cytoplasmic (Homo sapiens (Human))	BDBM50145676 (CHEMBL3764310) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of human leucyl-tRNA synthetase assessed as reduction of [14C]-L-leucine ligation to tRNA incubated for 5 mins by scintillation counting m...				Bioorg Med Chem 24: 1023-31 (2016) Article DOI: 10.1016/j.bmc.2016.01.028 BindingDB Entry DOI: 10.7270/Q2RN39Q8
NAS of Ukraine Curated by ChEMBL					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Homo sapiens (Human))	BDBM50145675 (CHEMBL3764493) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of human leucyl-tRNA synthetase assessed as reduction of [14C]-L-leucine ligation to tRNA incubated for 5 mins by scintillation counting m...				Bioorg Med Chem 24: 1023-31 (2016) Article DOI: 10.1016/j.bmc.2016.01.028 BindingDB Entry DOI: 10.7270/Q2RN39Q8
NAS of Ukraine Curated by ChEMBL					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Homo sapiens (Human))	BDBM50145677 (CHEMBL3765025) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of human leucyl-tRNA synthetase assessed as reduction of [14C]-L-leucine ligation to tRNA incubated for 5 mins by scintillation counting m...				Bioorg Med Chem 24: 1023-31 (2016) Article DOI: 10.1016/j.bmc.2016.01.028 BindingDB Entry DOI: 10.7270/Q2RN39Q8
NAS of Ukraine Curated by ChEMBL					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Homo sapiens (Human))	BDBM50145678 (CHEMBL3763921) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of human leucyl-tRNA synthetase assessed as reduction of [14C]-L-leucine ligation to tRNA incubated for 5 mins by scintillation counting m...				Bioorg Med Chem 24: 1023-31 (2016) Article DOI: 10.1016/j.bmc.2016.01.028 BindingDB Entry DOI: 10.7270/Q2RN39Q8
NAS of Ukraine Curated by ChEMBL					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Homo sapiens (Human))	BDBM50145674 (CHEMBL2436531) Show SMILES CCOC(=O)c1sc(N\N=C\c2ccc(O)c(OC)c2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of human leucyl-tRNA synthetase assessed as reduction of [14C]-L-leucine ligation to tRNA incubated for 5 mins by scintillation counting m...				Bioorg Med Chem 24: 1023-31 (2016) Article DOI: 10.1016/j.bmc.2016.01.028 BindingDB Entry DOI: 10.7270/Q2RN39Q8
NAS of Ukraine Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%