Affinity Data by PubMed id=26899595

PubMed code 26899595

Found 32 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM56150 ((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...) Show SMILES Cc1ccc(O)c(c1)-c1cc([nH]n1)-c1ccccc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Competitive inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by Dixon plot analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM79800 (5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...) Show SMILES CNc1oc(nc1C#N)-c1cccc2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50208823 (6,11-dihydrothiochromeno[4,3-b]indole \| CHEMBL1809...) Show SMILES C1Sc2ccccc2-c2[nH]c3ccccc3c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human 12/15-LOX expressed in HEK293 cells after 30 mins by microplate reader analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM56150 ((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...) Show SMILES Cc1ccc(O)c(c1)-c1cc([nH]n1)-c1ccccc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM49247 ((6Z)-6-[5-(2-chlorophenyl)-1,2-dihydropyrazol-3-yl...) Show SMILES Oc1ccccc1-c1cc([nH]n1)-c1ccccc1Cl Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50148015 (CHEMBL1540577) Show SMILES COc1ccc(cc1)-c1cc([nH]n1)-c1cc(OC)ccc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50187067 (2-(5-(2-chlorophenyl)-1H-pyrazol-3-yl)-4-methoxyph...) Show SMILES COc1ccc(O)c(c1)-c1cc(n[nH]1)-c1ccccc1Cl Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM57040 ((6E)-6-[5-(3-bromophenyl)-1,2-dihydropyrazol-3-yli...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50148019 (CHEMBL1604272) Show SMILES Cc1ccccc1-c1cc([nH]n1)-c1ccccc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50148017 (CHEMBL1353771) Show SMILES Oc1ccccc1-c1cc([nH]n1)-c1ccco1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50148023 (CHEMBL1448722) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50148018 (CHEMBL1372333) Show SMILES COc1ccc(cc1)-c1cc([nH]n1)-c1ccccc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM78048 ((6E)-6-[5-(3-fluorophenyl)-1,2-dihydropyrazol-3-yl...) Show SMILES Cc1ccc(O)c(c1)-c1cc([nH]n1)-c1cccc(F)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM49390 ((6Z)-3-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...) Show SMILES Cc1ccc(-c2cc([nH]n2)-c2ccccc2C)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM114790 ((6Z)-6-[5-(4-fluorophenyl)-1,2-dihydropyrazol-3-yl...) Show SMILES Cc1ccc(-c2cc([nH]n2)-c2ccc(F)cc2)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50148014 (CHEMBL1370300) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50148013 (CHEMBL1520849) Show SMILES Cc1ccc(-c2cc([nH]n2)-c2ccccc2Cl)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM49265 ((6Z)-6-[5-(3-fluorophenyl)-1,2-dihydropyrazol-3-yl...) Show SMILES Cc1ccc(-c2cc([nH]n2)-c2cccc(F)c2)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50148016 (CHEMBL1718182) Show SMILES Oc1ccccc1-c1cc([nH]n1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50147981 (CHEMBL1546898) Show SMILES Oc1ccc(Br)cc1-c1cc([nH]n1)-c1ccccc1Cl Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50147966 (CHEMBL1344000) Show SMILES Oc1ccc(Br)cc1-c1cc([nH]n1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM59267 ((5E)-5-(3-methyl-6-oxidanylidene-cyclohexa-2,4-die...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50148010 (CHEMBL584668 \| GNF-Pf-4068) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Homo sapiens (Human))	BDBM56150 ((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...) Show SMILES Cc1ccc(O)c(c1)-c1cc([nH]n1)-c1ccccc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 15-LOX-2 using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM24679 ((6Z)-6-(3-pyrazolin-3-ylidene)cyclohexa-2,4-dien-1...) Show SMILES Oc1ccccc1-c1cc[nH]n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50148011 (CHEMBL1328952) Show SMILES Cc1ccc(cc1)-c1cc([nH]n1)-c1ccc(C)cc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50148009 (CHEMBL375966) Show SMILES c1c(n[nH]c1-c1ccccc1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX12 (Homo sapiens (Human))	BDBM56150 ((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...) Show SMILES Cc1ccc(O)c(c1)-c1cc([nH]n1)-c1ccccc1C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50147986 (CHEMBL1442717) Show SMILES Oc1ccc(Cl)cc1-c1cc([nH]n1)-c1ccccc1Cl Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50148021 (CHEMBL1736078) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM56150 ((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...) Show SMILES Cc1ccc(O)c(c1)-c1cc([nH]n1)-c1ccccc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human 5-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM56150 ((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...) Show SMILES Cc1ccc(O)c(c1)-c1cc([nH]n1)-c1ccccc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human COX-2 by UV-visible spectrophotometric analysis				Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44
University of California Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%