Found 44 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50126186
(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)Show InChI InChI=1S/C21H17NO3/c1-14(16-11-10-15-6-2-3-7-17(15)13-16)12-20(23)22-19-9-5-4-8-18(19)21(24)25/h2-13H,1H3,(H,22,23)(H,24,25)/b14-12+ | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of human telomerase |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50446421
(CHEMBL3109740)Show SMILES C\C(=C/C(=O)Nc1ccc(cc1C(O)=O)N1CCOCC1)c1ccc2ccccc2c1 Show InChI InChI=1S/C25H24N2O4/c1-17(19-7-6-18-4-2-3-5-20(18)15-19)14-24(28)26-23-9-8-21(16-22(23)25(29)30)27-10-12-31-13-11-27/h2-9,14-16H,10-13H2,1H3,(H,26,28)(H,29,30)/b17-14+ | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of human telomerase |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160391
(CHEMBL3786231)Show SMILES CCCCN(CCCC)CC(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O |c:13| Show InChI InChI=1S/C28H33N3O3/c1-3-5-16-30(17-6-4-2)20-27(32)31-25(21-12-8-7-9-13-21)19-24(29-31)23-18-22-14-10-11-15-26(22)34-28(23)33/h7-15,18,25H,3-6,16-17,19-20H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160320
(CHEMBL3786261)Show InChI InChI=1S/C14H15ClN2O3/c1-9-7-12(17(16-9)14(19)8-15)11-5-3-4-6-13(11)20-10(2)18/h3-6,12H,7-8H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160330
(CHEMBL3785281)Show SMILES CN1CCN(CC(=O)N2N=C(C)CC2c2ccccc2O)CC1 |t:9| Show InChI InChI=1S/C17H24N4O2/c1-13-11-15(14-5-3-4-6-16(14)22)21(18-13)17(23)12-20-9-7-19(2)8-10-20/h3-6,15,22H,7-12H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160326
(CHEMBL3787380)Show SMILES CC(=O)Oc1ccccc1C1CC(C)=NN1C(=O)CN1CCCCC1 |c:14| Show InChI InChI=1S/C19H25N3O3/c1-14-12-17(16-8-4-5-9-18(16)25-15(2)23)22(20-14)19(24)13-21-10-6-3-7-11-21/h4-5,8-9,17H,3,6-7,10-13H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160312
(CHEMBL3786734)Show SMILES ClCC(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O |c:5| Show InChI InChI=1S/C20H15ClN2O3/c21-12-19(24)23-17(13-6-2-1-3-7-13)11-16(22-23)15-10-14-8-4-5-9-18(14)26-20(15)25/h1-10,17H,11-12H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160384
(CHEMBL3786296)Show SMILES FC(F)(F)c1ccccc1C1CC(=NN1C(=O)CN1CCOCC1)c1cc2ccccc2oc1=O |c:13| Show InChI InChI=1S/C25H22F3N3O4/c26-25(27,28)19-7-3-2-6-17(19)21-14-20(18-13-16-5-1-4-8-22(16)35-24(18)33)29-31(21)23(32)15-30-9-11-34-12-10-30/h1-8,13,21H,9-12,14-15H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160396
(CHEMBL3787509)Show SMILES CNCC(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O |c:6| Show InChI InChI=1S/C21H19N3O3/c1-22-13-20(25)24-18(14-7-3-2-4-8-14)12-17(23-24)16-11-15-9-5-6-10-19(15)27-21(16)26/h2-11,18,22H,12-13H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160381
(CHEMBL3781973)Show InChI InChI=1S/C12H12BrClN2O2/c1-7-4-10(16(15-7)12(18)6-14)9-5-8(13)2-3-11(9)17/h2-3,5,10,17H,4,6H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160392
(CHEMBL3787157)Show SMILES CC(C)CNCC(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O |c:9| Show InChI InChI=1S/C24H25N3O3/c1-16(2)14-25-15-23(28)27-21(17-8-4-3-5-9-17)13-20(26-27)19-12-18-10-6-7-11-22(18)30-24(19)29/h3-12,16,21,25H,13-15H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160386
(CHEMBL3785699)Show SMILES FC(F)(F)c1ccccc1C1CC(=NN1C(=O)CN1CCSCC1)c1cc2ccccc2oc1=O |c:13| Show InChI InChI=1S/C25H22F3N3O3S/c26-25(27,28)19-7-3-2-6-17(19)21-14-20(18-13-16-5-1-4-8-22(16)34-24(18)33)29-31(21)23(32)15-30-9-11-35-12-10-30/h1-8,13,21H,9-12,14-15H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160319
(CHEMBL3785712)Show SMILES CC[N+](C)(CC)CC(=O)N1N=C(C)CC1c1ccccc1OC |t:10| Show InChI InChI=1S/C18H28N3O2/c1-6-21(4,7-2)13-18(22)20-16(12-14(3)19-20)15-10-8-9-11-17(15)23-5/h8-11,16H,6-7,12-13H2,1-5H3/q+1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160394
(CHEMBL3786636)Show SMILES CC(C)NCC(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O |c:8| Show InChI InChI=1S/C23H23N3O3/c1-15(2)24-14-22(27)26-20(16-8-4-3-5-9-16)13-19(25-26)18-12-17-10-6-7-11-21(17)29-23(18)28/h3-12,15,20,24H,13-14H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160323
(CHEMBL3787476)Show SMILES CC(=O)Oc1ccccc1C1CC(C)=NN1C(=O)CN1CCC(CC1)C(C)=O |c:14| Show InChI InChI=1S/C21H27N3O4/c1-14-12-19(18-6-4-5-7-20(18)28-16(3)26)24(22-14)21(27)13-23-10-8-17(9-11-23)15(2)25/h4-7,17,19H,8-13H2,1-3H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160316
(CHEMBL3785112)Show SMILES CCC(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O |c:5| Show InChI InChI=1S/C21H18N2O3/c1-2-20(24)23-18(14-8-4-3-5-9-14)13-17(22-23)16-12-15-10-6-7-11-19(15)26-21(16)25/h3-12,18H,2,13H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160337
(CHEMBL3785686)Show SMILES CC1=NN(C(C1)c1cc(Br)cc(Br)c1O)C(=O)CCl |t:1| Show InChI InChI=1S/C12H11Br2ClN2O2/c1-6-2-10(17(16-6)11(18)5-15)8-3-7(13)4-9(14)12(8)19/h3-4,10,19H,2,5H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160334
(CHEMBL3787002)Show InChI InChI=1S/C17H23N3O2/c1-13-11-15(14-7-3-4-8-16(14)21)20(18-13)17(22)12-19-9-5-2-6-10-19/h3-4,7-8,15,21H,2,5-6,9-12H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160385
(CHEMBL3785474)Show SMILES CCCCCCN(CCCCCC)CC(=O)N1N=C(CC1c1ccccc1C(F)(F)F)c1cc2ccccc2oc1=O |c:17| Show InChI InChI=1S/C33H40F3N3O3/c1-3-5-7-13-19-38(20-14-8-6-4-2)23-31(40)39-29(25-16-10-11-17-27(25)33(34,35)36)22-28(37-39)26-21-24-15-9-12-18-30(24)42-32(26)41/h9-12,15-18,21,29H,3-8,13-14,19-20,22-23H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160333
(CHEMBL3785170)Show InChI InChI=1S/C16H21N3O2/c1-12-10-14(13-6-2-3-7-15(13)20)19(17-12)16(21)11-18-8-4-5-9-18/h2-3,6-7,14,20H,4-5,8-11H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160387
(CHEMBL3785907)Show SMILES CCN(CC)CC(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O |c:9| Show InChI InChI=1S/C24H25N3O3/c1-3-26(4-2)16-23(28)27-21(17-10-6-5-7-11-17)15-20(25-27)19-14-18-12-8-9-13-22(18)30-24(19)29/h5-14,21H,3-4,15-16H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160324
(CHEMBL3785833)Show SMILES CC(=O)Oc1ccccc1C1CC(C)=NN1C(=O)CN1CCC(O)CC1 |c:14| Show InChI InChI=1S/C19H25N3O4/c1-13-11-17(16-5-3-4-6-18(16)26-14(2)23)22(20-13)19(25)12-21-9-7-15(24)8-10-21/h3-6,15,17,24H,7-12H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160321
(CHEMBL3785758)Show SMILES CC1CCCCN1CC(=O)N1N=C(C)CC1c1ccccc1OC(C)=O |t:12| Show InChI InChI=1S/C20H27N3O3/c1-14-12-18(17-9-4-5-10-19(17)26-16(3)24)23(21-14)20(25)13-22-11-7-6-8-15(22)2/h4-5,9-10,15,18H,6-8,11-13H2,1-3H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160325
(CHEMBL3786451)Show SMILES CC(=O)Oc1ccccc1C1CC(C)=NN1C(=O)CN1CCCC1 |c:14| Show InChI InChI=1S/C18H23N3O3/c1-13-11-16(15-7-3-4-8-17(15)24-14(2)22)21(19-13)18(23)12-20-9-5-6-10-20/h3-4,7-8,16H,5-6,9-12H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160395
(CHEMBL3786821)Show SMILES CCNCC(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O |c:7| Show InChI InChI=1S/C22H21N3O3/c1-2-23-14-21(26)25-19(15-8-4-3-5-9-15)13-18(24-25)17-12-16-10-6-7-11-20(16)28-22(17)27/h3-12,19,23H,2,13-14H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160331
(CHEMBL3785664)Show SMILES CC1=NN(C(C1)c1ccccc1O)C(=O)CN1CCN(CC1)C(=O)OC(C)(C)C |t:1| Show InChI InChI=1S/C21H30N4O4/c1-15-13-17(16-7-5-6-8-18(16)26)25(22-15)19(27)14-23-9-11-24(12-10-23)20(28)29-21(2,3)4/h5-8,17,26H,9-14H2,1-4H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160322
(CHEMBL3785794)Show SMILES COC1CCN(CC(=O)N2N=C(C)CC2c2ccccc2OC)CC1 |t:10| Show InChI InChI=1S/C19H27N3O3/c1-14-12-17(16-6-4-5-7-18(16)25-3)22(20-14)19(23)13-21-10-8-15(24-2)9-11-21/h4-7,15,17H,8-13H2,1-3H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160317
(CHEMBL3785970)Show SMILES O=C(N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O)c1ccccc1 |c:3| Show InChI InChI=1S/C25H18N2O3/c28-24(18-11-5-2-6-12-18)27-22(17-9-3-1-4-10-17)16-21(26-27)20-15-19-13-7-8-14-23(19)30-25(20)29/h1-15,22H,16H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM2579
((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 8.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160393
(CHEMBL3786236)Show SMILES CCCNCC(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O |c:8| Show InChI InChI=1S/C23H23N3O3/c1-2-12-24-15-22(27)26-20(16-8-4-3-5-9-16)14-19(25-26)18-13-17-10-6-7-11-21(17)29-23(18)28/h3-11,13,20,24H,2,12,14-15H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160329
(CHEMBL3787163)Show SMILES CCCN(CCC)CC(=O)N1N=C(C)CC1c1cc(Br)ccc1O |t:11| Show InChI InChI=1S/C18H26BrN3O2/c1-4-8-21(9-5-2)12-18(24)22-16(10-13(3)20-22)15-11-14(19)6-7-17(15)23/h6-7,11,16,23H,4-5,8-10,12H2,1-3H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160383
(CHEMBL3785883)Show SMILES CC1=NN(C(C1)c1ccccc1O)C(=O)CCc1ccccc1 |t:1| Show InChI InChI=1S/C19H20N2O2/c1-14-13-17(16-9-5-6-10-18(16)22)21(20-14)19(23)12-11-15-7-3-2-4-8-15/h2-10,17,22H,11-13H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160318
(CHEMBL3787256)Show SMILES COc1ccccc1C1CC(C)=NN1C(=O)C[N+]1(C)CCCC1 |c:12| Show InChI InChI=1S/C18H26N3O2/c1-14-12-16(15-8-4-5-9-17(15)23-3)20(19-14)18(22)13-21(2)10-6-7-11-21/h4-5,8-9,16H,6-7,10-13H2,1-3H3/q+1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160328
(CHEMBL3785132)Show SMILES CC1=NN(C(C1)c1cc(Br)ccc1O)C(=O)CN(CC=C)CC=C |t:1| Show InChI InChI=1S/C18H22BrN3O2/c1-4-8-21(9-5-2)12-18(24)22-16(10-13(3)20-22)15-11-14(19)6-7-17(15)23/h4-7,11,16,23H,1-2,8-10,12H2,3H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160398
(CHEMBL3786130)Show SMILES Clc1ccccc1C(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O |c:11| Show InChI InChI=1S/C25H17ClN2O3/c26-20-12-6-5-11-18(20)24(29)28-22(16-8-2-1-3-9-16)15-21(27-28)19-14-17-10-4-7-13-23(17)31-25(19)30/h1-14,22H,15H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160327
(CHEMBL3786450)Show SMILES COc1ccccc1C1CC(C)=NN1C(=O)CN(C(C)C)C(C)C |c:12| Show InChI InChI=1S/C19H29N3O2/c1-13(2)21(14(3)4)12-19(23)22-17(11-15(5)20-22)16-9-7-8-10-18(16)24-6/h7-10,13-14,17H,11-12H2,1-6H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160336
(CHEMBL3785623)Show InChI InChI=1S/C13H14Br2N2O2/c1-3-12(18)17-11(4-7(2)16-17)9-5-8(14)6-10(15)13(9)19/h5-6,11,19H,3-4H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160332
(CHEMBL3785297)Show SMILES COc1ccc(NCC(=O)N2N=C(C)CC2c2ccccc2O)cc1 |t:11| Show InChI InChI=1S/C19H21N3O3/c1-13-11-17(16-5-3-4-6-18(16)23)22(21-13)19(24)12-20-14-7-9-15(25-2)10-8-14/h3-10,17,20,23H,11-12H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160388
(CHEMBL3787196)Show SMILES NC(=O)C1CCN(CC(=O)N2N=C(CC2c2ccccc2)c2cc3ccccc3oc2=O)CC1 |c:11| Show InChI InChI=1S/C26H26N4O4/c27-25(32)18-10-12-29(13-11-18)16-24(31)30-22(17-6-2-1-3-7-17)15-21(28-30)20-14-19-8-4-5-9-23(19)34-26(20)33/h1-9,14,18,22H,10-13,15-16H2,(H2,27,32) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160397
(CHEMBL3786403)Show SMILES [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O |c:14| Show InChI InChI=1S/C24H17N3O6S/c28-24-20(14-17-8-4-5-9-23(17)33-24)21-15-22(16-6-2-1-3-7-16)26(25-21)34(31,32)19-12-10-18(11-13-19)27(29)30/h1-14,22H,15H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160389
(CHEMBL3785101)Show SMILES O=C(CN1CCC(CC1)c1ccccc1)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O |c:18| Show InChI InChI=1S/C31H29N3O3/c35-30(21-33-17-15-23(16-18-33)22-9-3-1-4-10-22)34-28(24-11-5-2-6-12-24)20-27(32-34)26-19-25-13-7-8-14-29(25)37-31(26)36/h1-14,19,23,28H,15-18,20-21H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160335
(CHEMBL3787080)Show SMILES CC1=NN(C(C1)c1cc(Cl)ccc1O)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O |t:1| Show InChI InChI=1S/C16H14ClN3O5S/c1-10-8-15(14-9-11(17)2-7-16(14)21)19(18-10)26(24,25)13-5-3-12(4-6-13)20(22)23/h2-7,9,15,21H,8H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160382
(CHEMBL3787238)Show SMILES CC1=NN(C(C1)c1ccccc1O)C(=O)COc1ccc(Cl)cc1 |t:1| Show InChI InChI=1S/C18H17ClN2O3/c1-12-10-16(15-4-2-3-5-17(15)22)21(20-12)18(23)11-24-14-8-6-13(19)7-9-14/h2-9,16,22H,10-11H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50160390
(CHEMBL3786111)Show SMILES ClC1CCN(CC(=O)N2N=C(CC2c2ccccc2)c2cc3ccccc3oc2=O)CC1 |c:9| Show InChI InChI=1S/C25H24ClN3O3/c26-19-10-12-28(13-11-19)16-24(30)29-22(17-6-2-1-3-7-17)15-21(27-29)20-14-18-8-4-5-9-23(18)32-25(20)31/h1-9,14,19,22H,10-13,15-16H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay |
Eur J Med Chem 112: 231-51 (2016)
Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4 |
More data for this
Ligand-Target Pair | |
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