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PubMed code 26970660

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phospholipase A2, membrane associated


(Mus musculus)		BDBM50149981
PNG
(CHEMBL3769794)
Show SMILES CCCCCCCCCCCCCCC(=O)C(=O)N[C@@H](C(C)C)C(O)=O |r|
Show InChI InChI=1S/C23H22BrN5O5S/c1-26-23(32)18(12-21(30)29-20-11-10-16(24)13-27-20)28-22(31)15-8-6-14(7-9-15)17-4-2-3-5-19(17)35(25,33)34/h2-11,13,18H,12H2,1H3,(H,26,32)(H,28,31)(H2,25,33,34)(H,27,29,30)
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 68n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Inhibition of mouse group 2A secreted phospholipase A2 by fluorescence assay

Bioorg Med Chem 24: 1683-95 (2016)


Article DOI: 10.1016/j.bmc.2016.02.040
BindingDB Entry DOI: 10.7270/Q2JQ12WP
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50149981
PNG
(CHEMBL3769794)
Show SMILES CCCCCCCCCCCCCCC(=O)C(=O)N[C@@H](C(C)C)C(O)=O |r|
Show InChI InChI=1S/C23H22BrN5O5S/c1-26-23(32)18(12-21(30)29-20-11-10-16(24)13-27-20)28-22(31)15-8-6-14(7-9-15)17-4-2-3-5-19(17)35(25,33)34/h2-11,13,18H,12H2,1H3,(H,26,32)(H,28,31)(H2,25,33,34)(H,27,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 143n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Inhibition of human group 2A secreted phospholipase A2 by fluorescence assay

Bioorg Med Chem 24: 1683-95 (2016)


Article DOI: 10.1016/j.bmc.2016.02.040
BindingDB Entry DOI: 10.7270/Q2JQ12WP
More data for this
Ligand-Target Pair
Phospholipase A2 group V


(Homo sapiens (Human))		BDBM50149981
PNG
(CHEMBL3769794)
Show SMILES CCCCCCCCCCCCCCC(=O)C(=O)N[C@@H](C(C)C)C(O)=O |r|
Show InChI InChI=1S/C23H22BrN5O5S/c1-26-23(32)18(12-21(30)29-20-11-10-16(24)13-27-20)28-22(31)15-8-6-14(7-9-15)17-4-2-3-5-19(17)35(25,33)34/h2-11,13,18H,12H2,1H3,(H,26,32)(H,28,31)(H2,25,33,34)(H,27,29,30)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Inhibition of human group 5 secreted phospholipase A2 by fluorescence assay

Bioorg Med Chem 24: 1683-95 (2016)


Article DOI: 10.1016/j.bmc.2016.02.040
BindingDB Entry DOI: 10.7270/Q2JQ12WP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%