Found 23 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50158419
(CHEMBL3734798)Show SMILES C[C@@H](Oc1cc(cnc1N)-c1ccn(n1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl |r| Show InChI InChI=1S/C21H22Cl2FN5O/c1-12(19-15(22)2-3-16(24)20(19)23)30-18-10-13(11-27-21(18)25)17-6-9-29(28-17)14-4-7-26-8-5-14/h2-3,6,9-12,14,26H,4-5,7-8H2,1H3,(H2,25,27)/t12-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50156347
(CHEMBL3786898)Show SMILES Cn1cc(cn1)-c1ccc2n(CCOc3ccnc4cc(ccc34)-c3cnn(C)c3)c(=O)oc2c1 Show InChI InChI=1S/C26H22N6O3/c1-30-15-19(13-28-30)17-3-5-21-22(11-17)27-8-7-24(21)34-10-9-32-23-6-4-18(12-25(23)35-26(32)33)20-14-29-31(2)16-20/h3-8,11-16H,9-10H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50158407
(CHEMBL3787612)Show SMILES Cc1ccc2n(CCOc3ccnc4cc(ccc34)-c3cnn(C)c3)c(=O)oc2c1 Show InChI InChI=1S/C23H20N4O3/c1-15-3-6-20-22(11-15)30-23(28)27(20)9-10-29-21-7-8-24-19-12-16(4-5-18(19)21)17-13-25-26(2)14-17/h3-8,11-14H,9-10H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50161011
(CHEMBL3786136)Show InChI InChI=1S/C22H22N2O5/c1-15-3-6-19-21(13-15)29-22(25)24(19)9-10-28-20-7-8-23-18-14-16(4-5-17(18)20)27-12-11-26-2/h3-8,13-14H,9-12H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50157644
(CHEMBL3787354)Show SMILES Cc1ccc2n(CCOc3ccnc4cc(OCCCN5CCOCC5)ccc34)c(=O)oc2c1 Show InChI InChI=1S/C26H29N3O5/c1-19-3-6-23-25(17-19)34-26(30)29(23)12-16-33-24-7-8-27-22-18-20(4-5-21(22)24)32-13-2-9-28-10-14-31-15-11-28/h3-8,17-18H,2,9-16H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50157648
(CHEMBL3786610)Show SMILES Cc1ccc2n(CCOc3ccnc4cc(OCCN5CCOCC5)ccc34)c(=O)oc2c1 Show InChI InChI=1S/C25H27N3O5/c1-18-2-5-22-24(16-18)33-25(29)28(22)11-15-32-23-6-7-26-21-17-19(3-4-20(21)23)31-14-10-27-8-12-30-13-9-27/h2-7,16-17H,8-15H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50161094
(CHEMBL3785650)Show SMILES CN1CCN(CCCOc2ccc3c(OCCn4c5ccc(C)cc5oc4=O)ccnc3c2)CC1 Show InChI InChI=1S/C27H32N4O4/c1-20-4-7-24-26(18-20)35-27(32)31(24)15-17-34-25-8-9-28-23-19-21(5-6-22(23)25)33-16-3-10-30-13-11-29(2)12-14-30/h4-9,18-19H,3,10-17H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50156366
(CHEMBL3787278)Show SMILES COc1ccc2c(OCCn3c4ccc(cc4oc3=O)-c3cnn(C)c3)ccnc2c1 Show InChI InChI=1S/C23H20N4O4/c1-26-14-16(13-25-26)15-3-6-20-22(11-15)31-23(28)27(20)9-10-30-21-7-8-24-19-12-17(29-2)4-5-18(19)21/h3-8,11-14H,9-10H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50161096
(CHEMBL3786574)Show SMILES Cc1ccc2n(CCOc3ccnc4cc(OCCCN5CCCC5)ccc34)c(=O)oc2c1 Show InChI InChI=1S/C26H29N3O4/c1-19-5-8-23-25(17-19)33-26(30)29(23)14-16-32-24-9-10-27-22-18-20(6-7-21(22)24)31-15-4-13-28-11-2-3-12-28/h5-10,17-18H,2-4,11-16H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50158408
(CHEMBL3786217)Show SMILES Cc1ccc2n(CCOc3ccnc4cc(NCCCN5CCOCC5)ccc34)c(=O)oc2c1 Show InChI InChI=1S/C26H30N4O4/c1-19-3-6-23-25(17-19)34-26(31)30(23)13-16-33-24-7-9-28-22-18-20(4-5-21(22)24)27-8-2-10-29-11-14-32-15-12-29/h3-7,9,17-18,27H,2,8,10-16H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50161012
(CHEMBL3786924)Show InChI InChI=1S/C20H18N2O4/c1-13-3-6-17-19(11-13)26-20(23)22(17)9-10-25-18-7-8-21-16-12-14(24-2)4-5-15(16)18/h3-8,11-12H,9-10H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50157643
(CHEMBL3785213)Show InChI InChI=1S/C19H17N3O4/c1-24-13-3-4-14-15(11-13)21-7-6-17(14)25-9-8-22-16-5-2-12(20)10-18(16)26-19(22)23/h2-7,10-11H,8-9,20H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50155844
(CHEMBL3787383)Show SMILES Cc1ccc2n(Cc3cccc(NC(=O)OCCCN4CCOCC4)c3)c(=O)oc2c1 Show InChI InChI=1S/C23H27N3O5/c1-17-6-7-20-21(14-17)31-23(28)26(20)16-18-4-2-5-19(15-18)24-22(27)30-11-3-8-25-9-12-29-13-10-25/h2,4-7,14-15H,3,8-13,16H2,1H3,(H,24,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of N-terminal 6His-tagged human recombinant c-MET expressed in baculovirus infected Sf21 cells using poly Ala-Glu-Lys-Tyr (6:2:5:1) as sub... |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50158405
(CHEMBL3785800)Show SMILES Cc1ccc2n(CCOc3ccnc4cc(OCCCCN5CCOCC5)ccc34)c(=O)oc2c1 Show InChI InChI=1S/C27H31N3O5/c1-20-4-7-24-26(18-20)35-27(31)30(24)13-17-34-25-8-9-28-23-19-21(5-6-22(23)25)33-14-3-2-10-29-11-15-32-16-12-29/h4-9,18-19H,2-3,10-17H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50157645
(CHEMBL3787308)Show InChI InChI=1S/C20H18N2O5/c1-24-13-3-5-15-16(11-13)21-8-7-18(15)26-10-9-22-17-6-4-14(25-2)12-19(17)27-20(22)23/h3-8,11-12H,9-10H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50156351
(CHEMBL3786658)Show SMILES COc1ccc2c(OCCn3c4cc(ccc4oc3=O)-c3cnn(C)c3)ccnc2c1 Show InChI InChI=1S/C23H20N4O4/c1-26-14-16(13-25-26)15-3-6-22-20(11-15)27(23(28)31-22)9-10-30-21-7-8-24-19-12-17(29-2)4-5-18(19)21/h3-8,11-14H,9-10H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50158417
(CHEMBL3786588)Show InChI InChI=1S/C20H18N2O4/c1-13-3-6-19-17(11-13)22(20(23)26-19)9-10-25-18-7-8-21-16-12-14(24-2)4-5-15(16)18/h3-8,11-12H,9-10H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079558
(CHEMBL3417482)Show SMILES CN1CCN(CCCOC(=O)Nc2cccc(Cn3nc(ccc3=O)-n3ccc4ccc(F)cc34)c2)CC1 Show InChI InChI=1S/C28H31FN6O3/c1-32-13-15-33(16-14-32)11-3-17-38-28(37)30-24-5-2-4-21(18-24)20-35-27(36)9-8-26(31-35)34-12-10-22-6-7-23(29)19-25(22)34/h2,4-10,12,18-19H,3,11,13-17,20H2,1H3,(H,30,37) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50161010
(CHEMBL3785106)Show SMILES COC(=O)c1ccc2n(CCOc3ccnc4cc(OC)ccc34)c(=O)oc2c1 Show InChI InChI=1S/C21H18N2O6/c1-26-14-4-5-15-16(12-14)22-8-7-18(15)28-10-9-23-17-6-3-13(20(24)27-2)11-19(17)29-21(23)25/h3-8,11-12H,9-10H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50161009
(CHEMBL3786146)Show InChI InChI=1S/C19H15FN2O4/c1-24-13-3-4-14-15(11-13)21-7-6-17(14)25-9-8-22-16-5-2-12(20)10-18(16)26-19(22)23/h2-7,10-11H,8-9H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50157647
(CHEMBL3787185)Show SMILES COc1ccc2c(OCCn3c4ccc(cc4oc3=O)N3CCOCC3)ccnc2c1 Show InChI InChI=1S/C23H23N3O5/c1-28-17-3-4-18-19(15-17)24-7-6-21(18)30-13-10-26-20-5-2-16(14-22(20)31-23(26)27)25-8-11-29-12-9-25/h2-7,14-15H,8-13H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50161095
(CHEMBL3786753)Show SMILES COC(=O)c1ccc2oc(=O)n(CCOc3ccnc4cc(OC)ccc34)c2c1 Show InChI InChI=1S/C21H18N2O6/c1-26-14-4-5-15-16(12-14)22-8-7-18(15)28-10-9-23-17-11-13(20(24)27-2)3-6-19(17)29-21(23)25/h3-8,11-12H,9-10H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50158421
(CHEMBL3787205)Show InChI InChI=1S/C19H15FN2O4/c1-24-13-3-4-14-15(11-13)21-7-6-17(14)25-9-8-22-16-10-12(20)2-5-18(16)26-19(22)23/h2-7,10-11H,8-9H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
Eur J Med Chem 115: 191-200 (2016)
Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9 |
More data for this
Ligand-Target Pair | |
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