BindingDB logo
myBDB logout

PubMed code 27096053

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50174316
PNG
(CHEMBL3809355)
Show SMILES CCCCCCC(C)(C)c1cc(O)c(C2CCCCC2)c(O)c1
Show InChI InChI=1S/C21H34O2/c1-4-5-6-10-13-21(2,3)17-14-18(22)20(19(23)15-17)16-11-8-7-9-12-16/h14-16,22-23H,4-13H2,1-3H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
11n/an/an/an/an/an/an/an/a



KannaLife Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]CP 55940 from human CB1 receptor after 1 hr by liquid scintillation spectrometry


ACS Med Chem Lett 7: 424-8 (2016)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50092588
PNG
(4-(1,1-Dimethyl-heptyl)-2'-isopropyl-5'-methyl-bip...)
Show SMILES CCCCCCC(C)(C)c1ccc(c(O)c1)-c1cc(C)ccc1C(C)C
Show InChI InChI=1S/C25H36O/c1-7-8-9-10-15-25(5,6)20-12-14-22(24(26)17-20)23-16-19(4)11-13-21(23)18(2)3/h11-14,16-18,26H,7-10,15H2,1-6H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
33n/an/an/an/an/an/an/an/a



KannaLife Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]CP 55940 from human CB1 receptor after 1 hr by liquid scintillation spectrometry


ACS Med Chem Lett 7: 424-8 (2016)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50174315
PNG
(CHEMBL3810140)
Show SMILES CCCCCc1cc(O)c([C@H]2C=C(C)CC[C@@H]2C(C)=C)c(O)c1 |r,t:11|
Show InChI InChI=1/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/s2
PDB

Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
842n/an/an/an/an/an/an/an/a



KannaLife Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]-HU-243 from CB1 receptor in Sabra rat brain synaptosomes after 90 mins


ACS Med Chem Lett 7: 424-8 (2016)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50318484
PNG
(2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)...)
Show SMILES CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1 |r,t:11|
Show InChI InChI=1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1
PDB

Reactome pathway
KEGG

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents

PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



KannaLife Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]-HU-243 from CB1 receptor in Sabra rat brain synaptosomes after 90 mins


ACS Med Chem Lett 7: 424-8 (2016)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%