Affinity Data by PubMed id=27982494

PubMed code 27982494

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Plasma kallikrein (Homo sapiens (Human))	BDBM218837 (TBMB-PK15 (10)) Show SMILES CSCc1cc(CSC)cc(CSC)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Glasgow					Assay Description The inhibition of plasma kallikrein and coagulation factor FXII was assessed by incubating the proteases with bicyclic peptide (twofold dilutions) an...				Chembiochem 18: 387-395 (2017) Article DOI: 10.1002/cbic.201600612 BindingDB Entry DOI: 10.7270/Q2H9942B
University of Glasgow					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM218839 (TBMT-FX618 (16) \| TBMT-PK15 (12)) Show SMILES CSCc1nc(CSC)nc(CSC)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Glasgow					Assay Description The inhibition of plasma kallikrein and coagulation factor FXII was assessed by incubating the proteases with bicyclic peptide (twofold dilutions) an...				Chembiochem 18: 387-395 (2017) Article DOI: 10.1002/cbic.201600612 BindingDB Entry DOI: 10.7270/Q2H9942B
University of Glasgow					More data for this Ligand-Target Pair
Coagulation factor XII (Homo sapiens (Human))	BDBM218840 (TATA-FXII618 (14)) Show SMILES CSCCC(=O)N1CN(CN(C1)C(=O)CCSC)C(=O)CCSC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Glasgow					Assay Description The inhibition of plasma kallikrein and coagulation factor FXII was assessed by incubating the proteases with bicyclic peptide (twofold dilutions) an...				Chembiochem 18: 387-395 (2017) Article DOI: 10.1002/cbic.201600612 BindingDB Entry DOI: 10.7270/Q2H9942B
University of Glasgow					More data for this Ligand-Target Pair
Coagulation factor XII (Homo sapiens (Human))	BDBM218838 (TATB-FXII618 (15) \| TATB-PK15 (11)) Show SMILES CSCC(=O)N1CN(CN(C1)C(=O)CSC)C(=O)CSC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Glasgow					Assay Description The inhibition of plasma kallikrein and coagulation factor FXII was assessed by incubating the proteases with bicyclic peptide (twofold dilutions) an...				Chembiochem 18: 387-395 (2017) Article DOI: 10.1002/cbic.201600612 BindingDB Entry DOI: 10.7270/Q2H9942B
University of Glasgow					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM218838 (TATB-FXII618 (15) \| TATB-PK15 (11)) Show SMILES CSCC(=O)N1CN(CN(C1)C(=O)CSC)C(=O)CSC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	540	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Glasgow					Assay Description The inhibition of plasma kallikrein and coagulation factor FXII was assessed by incubating the proteases with bicyclic peptide (twofold dilutions) an...				Chembiochem 18: 387-395 (2017) Article DOI: 10.1002/cbic.201600612 BindingDB Entry DOI: 10.7270/Q2H9942B
University of Glasgow					More data for this Ligand-Target Pair
Coagulation factor XII (Homo sapiens (Human))	BDBM218839 (TBMT-FX618 (16) \| TBMT-PK15 (12)) Show SMILES CSCc1nc(CSC)nc(CSC)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Glasgow					Assay Description The inhibition of plasma kallikrein and coagulation factor FXII was assessed by incubating the proteases with bicyclic peptide (twofold dilutions) an...				Chembiochem 18: 387-395 (2017) Article DOI: 10.1002/cbic.201600612 BindingDB Entry DOI: 10.7270/Q2H9942B
University of Glasgow					More data for this Ligand-Target Pair

* indicates data uncertainty>20%