Affinity Data by PubMed id=2840499

PubMed code 2840499

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50013094 (2-Phenylamino-1,9-dihydro-purin-6-one \| 2-Phenylam...) Show SMILES O=c1[nH]c(Nc2ccccc2)nc2nc[nH]c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to torpedo electroplax membranes				J Med Chem 31: 1496-500 (1988) BindingDB Entry DOI: 10.7270/Q2930TR7
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50405103 (CHEMBL2115349) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description Inhibitory activity against Herpes simplex virus type-I specific thymidine kinase				J Med Chem 31: 1496-500 (1988) BindingDB Entry DOI: 10.7270/Q2930TR7
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50123605 (CHEMBL3143935) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 1496-500 (1988) BindingDB Entry DOI: 10.7270/Q2930TR7
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50013095 (2-p-Tolylamino-1,9-dihydro-purin-6-one \| CHEMBL368...) Show SMILES Cc1ccc(Nc2nc3nc[nH]c3c(=O)[nH]2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description Inhibitory activity against Herpes simplex virus type-I specific thymidine kinase				J Med Chem 31: 1496-500 (1988) BindingDB Entry DOI: 10.7270/Q2930TR7
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50367744 (CHEMBL603175) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 1496-500 (1988) BindingDB Entry DOI: 10.7270/Q2930TR7
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50013075 (2-(Indan-5-ylamino)-1,9-dihydro-purin-6-one \| CHEM...) Show SMILES O=c1[nH]c(Nc2ccc3CCCc3c2)nc2nc[nH]c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to torpedo electroplax membranes				J Med Chem 31: 1496-500 (1988) BindingDB Entry DOI: 10.7270/Q2930TR7
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50018915 (2-(4-Butyl-phenylamino)-9-(2-hydroxy-ethoxymethyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to torpedo electroplax membranes				J Med Chem 31: 1496-500 (1988) BindingDB Entry DOI: 10.7270/Q2930TR7
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50013093 (2-(3-Ethyl-4-methyl-phenylamino)-1,9-dihydro-purin...) Show SMILES CCc1cc(Nc2nc3nc[nH]c3c(=O)[nH]2)ccc1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description Inhibition of (-)-[3H]-nicotine binding to rat brain membranes				J Med Chem 31: 1496-500 (1988) BindingDB Entry DOI: 10.7270/Q2930TR7
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50123607 (CHEMBL3143943) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranes				J Med Chem 31: 1496-500 (1988) BindingDB Entry DOI: 10.7270/Q2930TR7
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50013074 (2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one \| ...) Show SMILES CCCCc1ccc(Nc2nc3nc[nH]c3c(=O)[nH]2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to torpedo electroplax membranes				J Med Chem 31: 1496-500 (1988) BindingDB Entry DOI: 10.7270/Q2930TR7
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50123606 (CHEMBL3143941) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranes				J Med Chem 31: 1496-500 (1988) BindingDB Entry DOI: 10.7270/Q2930TR7
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50405722 (CHEMBL2092762) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description Inhibitory activity against Herpes simplex virus type-I specific thymidine kinase				J Med Chem 31: 1496-500 (1988) BindingDB Entry DOI: 10.7270/Q2930TR7
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50013099 (2-(3-Ethyl-phenylamino)-1,9-dihydro-purin-6-one \| ...) Show SMILES CCc1cccc(Nc2nc3nc[nH]c3c(=O)[nH]2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description Inhibitory activity against Herpes simplex virus type-I specific thymidine kinase				J Med Chem 31: 1496-500 (1988) BindingDB Entry DOI: 10.7270/Q2930TR7
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%