Affinity Data by PubMed id=28523099

PubMed code 28523099

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
NT-3 growth factor receptor (Homo sapiens (Human))	BDBM50232773 (CHEMBL4091670) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human TrkC using poly[Glu:Tyr] (4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 2 hrs by H...				ACS Med Chem Lett 8: 492-497 (2017) Article DOI: 10.1021/acsmedchemlett.6b00468 BindingDB Entry DOI: 10.7270/Q2RV0QZ9
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50232773 (CHEMBL4091670) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 2 hrs by ...				ACS Med Chem Lett 8: 492-497 (2017) Article DOI: 10.1021/acsmedchemlett.6b00468 BindingDB Entry DOI: 10.7270/Q2RV0QZ9
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50232773 (CHEMBL4091670) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human FLT3 using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 2 hrs by Hotspot ...				ACS Med Chem Lett 8: 492-497 (2017) Article DOI: 10.1021/acsmedchemlett.6b00468 BindingDB Entry DOI: 10.7270/Q2RV0QZ9
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50232774 (CHEMBL4061775) Show SMILES Nc1ncc2ccc(Cl)cc2c1C#Cc1cccc(c1)C(=N)NO Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	217	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human FLT3 using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 2 hrs by Hotspot ...				ACS Med Chem Lett 8: 492-497 (2017) Article DOI: 10.1021/acsmedchemlett.6b00468 BindingDB Entry DOI: 10.7270/Q2RV0QZ9
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50232775 (CHEMBL4078141) Show SMILES Nc1ncc2ccc(Cl)cc2c1C#Cc1ccc(cc1)C(=N)NO Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	359	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human FLT3 using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 2 hrs by Hotspot ...				ACS Med Chem Lett 8: 492-497 (2017) Article DOI: 10.1021/acsmedchemlett.6b00468 BindingDB Entry DOI: 10.7270/Q2RV0QZ9
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%