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PubMed code 28648463

Compile data set for download or QSAR
Found 19 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268638
PNG
(CHEMBL4080356)
Show SMILES CCCc1cnc(nc1)N1CCC(CC1)n1nnc2c(Nc3ccc(cc3F)S(C)(=O)=O)ncnc12
Show InChI InChI=1S/C23H26FN9O2S/c1-3-4-15-12-25-23(26-13-15)32-9-7-16(8-10-32)33-22-20(30-31-33)21(27-14-28-22)29-19-6-5-17(11-18(19)24)36(2,34)35/h5-6,11-14,16H,3-4,7-10H2,1-2H3,(H,27,28,29)
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n/an/an/an/a 82n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in HEK293 cells by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268631
PNG
(CHEMBL4104336)
Show SMILES CC(=O)c1cnc(nc1)N1CCC(CC1)c1coc2c(ncnc12)N1CCc2cc(ccc12)S(C)(=O)=O
Show InChI InChI=1S/C26H26N6O4S/c1-16(33)19-12-27-26(28-13-19)31-8-5-17(6-9-31)21-14-36-24-23(21)29-15-30-25(24)32-10-7-18-11-20(37(2,34)35)3-4-22(18)32/h3-4,11-15,17H,5-10H2,1-2H3
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n/an/an/an/a 78n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268623
PNG
(CHEMBL4063942)
Show SMILES COc1cnc(nc1)N1CCC(CC1)c1coc2c(ncnc12)N1CCc2cc(ccc12)S(C)(=O)=O
Show InChI InChI=1S/C25H26N6O4S/c1-34-18-12-26-25(27-13-18)30-8-5-16(6-9-30)20-14-35-23-22(20)28-15-29-24(23)31-10-7-17-11-19(36(2,32)33)3-4-21(17)31/h3-4,11-16H,5-10H2,1-2H3
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n/an/an/an/a 310n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268608
PNG
(CHEMBL4072360)
Show SMILES CN(c1ccc(cc1F)S(C)(=O)=O)c1ncnc2c(coc12)C1CCN(CC1)C(=O)OC(C)(C)C
Show InChI InChI=1S/C24H29FN4O5S/c1-24(2,3)34-23(30)29-10-8-15(9-11-29)17-13-33-21-20(17)26-14-27-22(21)28(4)19-7-6-16(12-18(19)25)35(5,31)32/h6-7,12-15H,8-11H2,1-5H3
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n/an/an/an/a>1.00E+3n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268622
PNG
(CHEMBL4077670)
Show SMILES CS(=O)(=O)c1ccc2N(CCc2c1)c1ncnc2c(coc12)C1CCN(CC1)c1ncc(F)cn1
Show InChI InChI=1S/C24H23FN6O3S/c1-35(32,33)18-2-3-20-16(10-18)6-9-31(20)23-22-21(28-14-29-23)19(13-34-22)15-4-7-30(8-5-15)24-26-11-17(25)12-27-24/h2-3,10-15H,4-9H2,1H3
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n/an/an/an/a 201n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268640
PNG
(CHEMBL4066674)
Show SMILES Cc1cnc(nc1)N1CCC(CC1)c1coc2c(ncnc12)N1CCc2cc(ccc12)S(C)(=O)=O
Show InChI InChI=1S/C25H26N6O3S/c1-16-12-26-25(27-13-16)30-8-5-17(6-9-30)20-14-34-23-22(20)28-15-29-24(23)31-10-7-18-11-19(35(2,32)33)3-4-21(18)31/h3-4,11-15,17H,5-10H2,1-2H3
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n/an/an/an/a 252n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268618
PNG
(CHEMBL4083015)
Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)c1c[nH]c2c(Nc3ccc(cc3F)S(C)(=O)=O)ncnc12
Show InChI InChI=1S/C23H28FN5O4S/c1-23(2,3)33-22(30)29-9-7-14(8-10-29)16-12-25-20-19(16)26-13-27-21(20)28-18-6-5-15(11-17(18)24)34(4,31)32/h5-6,11-14,25H,7-10H2,1-4H3,(H,26,27,28)
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n/an/an/an/a>1.00E+3n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268621
PNG
(CHEMBL4101938)
Show SMILES CS(=O)(=O)c1ccc2N(CCc2c1)c1ncnc2c(coc12)C1CCN(CC1)c1ncc(Cl)cn1
Show InChI InChI=1S/C24H23ClN6O3S/c1-35(32,33)18-2-3-20-16(10-18)6-9-31(20)23-22-21(28-14-29-23)19(13-34-22)15-4-7-30(8-5-15)24-26-11-17(25)12-27-24/h2-3,10-15H,4-9H2,1H3
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n/an/an/an/a 42n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268624
PNG
(CHEMBL4085517)
Show SMILES CS(=O)(=O)c1ccc2N(CCc2c1)c1ncnc2c(coc12)C1CCN(CC1)c1ncc(O)cn1
Show InChI InChI=1S/C24H24N6O4S/c1-35(32,33)18-2-3-20-16(10-18)6-9-30(20)23-22-21(27-14-28-23)19(13-34-22)15-4-7-29(8-5-15)24-25-11-17(31)12-26-24/h2-3,10-15,31H,4-9H2,1H3
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n/an/an/an/a 391n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268607
PNG
(CHEMBL4060970)
Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)c1coc2c(ncnc12)N1CCCc2cc(ccc12)S(C)(=O)=O
Show InChI InChI=1S/C26H32N4O5S/c1-26(2,3)35-25(31)29-12-9-17(10-13-29)20-15-34-23-22(20)27-16-28-24(23)30-11-5-6-18-14-19(36(4,32)33)7-8-21(18)30/h7-8,14-17H,5-6,9-13H2,1-4H3
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n/an/an/an/a 793n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268641
PNG
(CHEMBL4079439)
Show SMILES CS(=O)(=O)c1ccc2N(CCc2c1)c1ncnc2c(coc12)C1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C24H24N6O3S/c1-34(31,32)18-3-4-20-17(13-18)7-12-30(20)23-22-21(27-15-28-23)19(14-33-22)16-5-10-29(11-6-16)24-25-8-2-9-26-24/h2-4,8-9,13-16H,5-7,10-12H2,1H3
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n/an/an/an/a 512n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268614
PNG
(CHEMBL4098382)
Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)c1coc2c(Nc3ccc(cc3F)S(C)(=O)=O)ncnc12
Show InChI InChI=1S/C23H27FN4O5S/c1-23(2,3)33-22(29)28-9-7-14(8-10-28)16-12-32-20-19(16)25-13-26-21(20)27-18-6-5-15(11-17(18)24)34(4,30)31/h5-6,11-14H,7-10H2,1-4H3,(H,25,26,27)
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n/an/an/an/a 129n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268630
PNG
(CHEMBL4086445)
Show SMILES CC(O)c1cnc(nc1)N1CCC(CC1)c1coc2c(ncnc12)N1CCc2cc(ccc12)S(C)(=O)=O
Show InChI InChI=1S/C26H28N6O4S/c1-16(33)19-12-27-26(28-13-19)31-8-5-17(6-9-31)21-14-36-24-23(21)29-15-30-25(24)32-10-7-18-11-20(37(2,34)35)3-4-22(18)32/h3-4,11-17,33H,5-10H2,1-2H3
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n/an/an/an/a 586n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268637
PNG
(CHEMBL4094202)
Show SMILES CCc1cnc(nc1)N1CCC(CC1)c1coc2c(ncnc12)N1CCc2cc(ccc12)S(C)(=O)=O
Show InChI InChI=1S/C26H28N6O3S/c1-3-17-13-27-26(28-14-17)31-9-6-18(7-10-31)21-15-35-24-23(21)29-16-30-25(24)32-11-8-19-12-20(36(2,33)34)4-5-22(19)32/h4-5,12-16,18H,3,6-11H2,1-2H3
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n/an/an/an/a 41n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268639
PNG
(CHEMBL4099566)
Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)n1nnc2c(Nc3ccc(cc3F)S(C)(=O)=O)ncnc12
Show InChI InChI=1S/C21H26FN7O4S/c1-21(2,3)33-20(30)28-9-7-13(8-10-28)29-19-17(26-27-29)18(23-12-24-19)25-16-6-5-14(11-15(16)22)34(4,31)32/h5-6,11-13H,7-10H2,1-4H3,(H,23,24,25)
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n/an/an/an/a 19n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in HEK293 cells by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268613
PNG
(CHEMBL4099307)
Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)c1coc2c(ncnc12)N1CCc2cc(ccc12)S(C)(=O)=O
Show InChI InChI=1S/C25H30N4O5S/c1-25(2,3)34-24(30)28-10-7-16(8-11-28)19-14-33-22-21(19)26-15-27-23(22)29-12-9-17-13-18(35(4,31)32)5-6-20(17)29/h5-6,13-16H,7-12H2,1-4H3
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n/an/an/an/a 53n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268615
PNG
(CHEMBL4065753)
Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)c1noc2c(Nc3ccc(cc3F)S(C)(=O)=O)ncnc12
Show InChI InChI=1S/C22H26FN5O5S/c1-22(2,3)32-21(29)28-9-7-13(8-10-28)17-18-19(33-27-17)20(25-12-24-18)26-16-6-5-14(11-15(16)23)34(4,30)31/h5-6,11-13H,7-10H2,1-4H3,(H,24,25,26)
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n/an/an/an/a 353n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268619
PNG
(CHEMBL4100997)
Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)c1csc2c(Nc3ccc(cc3F)S(C)(=O)=O)ncnc12
Show InChI InChI=1S/C23H27FN4O4S2/c1-23(2,3)32-22(29)28-9-7-14(8-10-28)16-12-33-20-19(16)25-13-26-21(20)27-18-6-5-15(11-17(18)24)34(4,30)31/h5-6,11-14H,7-10H2,1-4H3,(H,25,26,27)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 79n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50268617
PNG
(CHEMBL4093367)
Show SMILES Cn1cc(C2CCN(CC2)C(=O)OC(C)(C)C)c2ncnc(Nc3ccc(cc3F)S(C)(=O)=O)c12
Show InChI InChI=1S/C24H30FN5O4S/c1-24(2,3)34-23(31)30-10-8-15(9-11-30)17-13-29(4)21-20(17)26-14-27-22(21)28-19-7-6-16(12-18(19)25)35(5,32)33/h6-7,12-15H,8-11H2,1-5H3,(H,26,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 27: 3249-3253 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.034
BindingDB Entry DOI: 10.7270/Q2TB19CJ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%