Found 84 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510385
(CHEMBL4462979)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(F)cc3OC)c21 Show InChI InChI=1S/C23H21FN4O4S2/c1-31-15-4-6-16(7-5-15)34(29,30)28-10-9-17-20(12-28)33-23-21(17)22(25-13-26-23)27-18-8-3-14(24)11-19(18)32-2/h3-8,11,13H,9-10,12H2,1-2H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510412
(CHEMBL4532338)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(F)cc3F)c21 Show InChI InChI=1S/C22H18F2N4O3S2/c1-31-14-3-5-15(6-4-14)33(29,30)28-9-8-16-19(11-28)32-22-20(16)21(25-12-26-22)27-18-7-2-13(23)10-17(18)24/h2-7,10,12H,8-9,11H2,1H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510403
(CHEMBL4521686)Show InChI InChI=1S/C17H17FN4OS/c1-22-6-5-11-14(8-22)24-17-15(11)16(19-9-20-17)21-12-4-3-10(18)7-13(12)23-2/h3-4,7,9H,5-6,8H2,1-2H3,(H,19,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510410
(CHEMBL4450446)Show SMILES COc1cc(F)ccc1Nc1ncnc2sc3CN(CCc3c12)S(=O)(=O)c1ccc(F)cc1F Show InChI InChI=1S/C22H17F3N4O3S2/c1-32-17-9-13(24)2-4-16(17)28-21-20-14-6-7-29(10-18(14)33-22(20)27-11-26-21)34(30,31)19-5-3-12(23)8-15(19)25/h2-5,8-9,11H,6-7,10H2,1H3,(H,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510374
(CHEMBL4450194)Show SMILES COc1cc(F)ccc1Nc1ncnc2sc3CN(CCc3c12)S(=O)(=O)c1cccs1 Show InChI InChI=1S/C20H17FN4O3S3/c1-28-15-9-12(21)4-5-14(15)24-19-18-13-6-7-25(31(26,27)17-3-2-8-29-17)10-16(13)30-20(18)23-11-22-19/h2-5,8-9,11H,6-7,10H2,1H3,(H,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 940 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510364
(CHEMBL4554398)Show SMILES Fc1ccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2cccs2)c(Br)c1 Show InChI InChI=1S/C19H14BrFN4O2S3/c20-13-8-11(21)3-4-14(13)24-18-17-12-5-6-25(30(26,27)16-2-1-7-28-16)9-15(12)29-19(17)23-10-22-18/h1-4,7-8,10H,5-6,9H2,(H,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510421
(CHEMBL4537838)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(F)cc3Br)c21 Show InChI InChI=1S/C22H18BrFN4O3S2/c1-31-14-3-5-15(6-4-14)33(29,30)28-9-8-16-19(11-28)32-22-20(16)21(25-12-26-22)27-18-7-2-13(24)10-17(18)23/h2-7,10,12H,8-9,11H2,1H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510429
(CHEMBL4447000)Show SMILES COc1cc(F)ccc1Nc1ncnc2sc3CN(Cc4ccccc4)CCc3c12 Show InChI InChI=1S/C23H21FN4OS/c1-29-19-11-16(24)7-8-18(19)27-22-21-17-9-10-28(12-15-5-3-2-4-6-15)13-20(17)30-23(21)26-14-25-22/h2-8,11,14H,9-10,12-13H2,1H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510386
(CHEMBL4569877)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(Br)cc3)c21 Show InChI InChI=1S/C22H19BrN4O3S2/c1-30-16-6-8-17(9-7-16)32(28,29)27-11-10-18-19(12-27)31-22-20(18)21(24-13-25-22)26-15-4-2-14(23)3-5-15/h2-9,13H,10-12H2,1H3,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510370
(CHEMBL4443233)Show SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(F)cc3F)c21 Show InChI InChI=1S/C21H15F2N5O4S2/c22-12-5-6-15(14(23)9-12)26-20-19-13-7-8-27(10-17(13)33-21(19)25-11-24-20)34(31,32)18-4-2-1-3-16(18)28(29)30/h1-6,9,11H,7-8,10H2,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510426
(CHEMBL4540853)Show InChI InChI=1S/C16H14F2N4S/c1-22-5-4-10-13(7-22)23-16-14(10)15(19-8-20-16)21-12-3-2-9(17)6-11(12)18/h2-3,6,8H,4-5,7H2,1H3,(H,19,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510442
(CHEMBL4467722)Show SMILES COc1cc(F)ccc1Nc1ncnc2sc3CN(CCc3c12)S(=O)(=O)c1ccccc1[N+]([O-])=O Show InChI InChI=1S/C22H18FN5O5S2/c1-33-17-10-13(23)6-7-15(17)26-21-20-14-8-9-27(11-18(14)34-22(20)25-12-24-21)35(31,32)19-5-3-2-4-16(19)28(29)30/h2-7,10,12H,8-9,11H2,1H3,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510432
(CHEMBL4593296)Show SMILES Fc1ccc(Nc2ncnc3sc4CN(Cc5ccccc5)CCc4c23)c(F)c1 Show InChI InChI=1S/C22H18F2N4S/c23-15-6-7-18(17(24)10-15)27-21-20-16-8-9-28(11-14-4-2-1-3-5-14)12-19(16)29-22(20)26-13-25-21/h1-7,10,13H,8-9,11-12H2,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510419
(CHEMBL4466788)Show SMILES Fc1ccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2ccc(F)cc2F)c(F)c1 Show InChI InChI=1S/C21H14F4N4O2S2/c22-11-1-3-16(14(24)7-11)28-20-19-13-5-6-29(9-17(13)32-21(19)27-10-26-20)33(30,31)18-4-2-12(23)8-15(18)25/h1-4,7-8,10H,5-6,9H2,(H,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510407
(CHEMBL4472464)Show SMILES Fc1ccc(Nc2ncnc3sc4CN(Cc5ccccc5)CCc4c23)c(Br)c1 Show InChI InChI=1S/C22H18BrFN4S/c23-17-10-15(24)6-7-18(17)27-21-20-16-8-9-28(11-14-4-2-1-3-5-14)12-19(16)29-22(20)26-13-25-21/h1-7,10,13H,8-9,11-12H2,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510366
(CHEMBL4459257)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(Cl)cc3F)c21 Show InChI InChI=1S/C22H18ClFN4O3S2/c1-31-14-3-5-15(6-4-14)33(29,30)28-9-8-16-19(11-28)32-22-20(16)21(25-12-26-22)27-18-7-2-13(23)10-17(18)24/h2-7,10,12H,8-9,11H2,1H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510367
(CHEMBL4590109)Show SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(F)cc3Br)c21 Show InChI InChI=1S/C21H15BrFN5O4S2/c22-14-9-12(23)5-6-15(14)26-20-19-13-7-8-27(10-17(13)33-21(19)25-11-24-20)34(31,32)18-4-2-1-3-16(18)28(29)30/h1-6,9,11H,7-8,10H2,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510422
(CHEMBL4448106)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(Cl)cc3)c21 Show InChI InChI=1S/C22H19ClN4O3S2/c1-30-16-6-8-17(9-7-16)32(28,29)27-11-10-18-19(12-27)31-22-20(18)21(24-13-25-22)26-15-4-2-14(23)3-5-15/h2-9,13H,10-12H2,1H3,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510369
(CHEMBL4516825)Show SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(Br)cc3)c21 Show InChI InChI=1S/C21H16BrN5O4S2/c22-13-5-7-14(8-6-13)25-20-19-15-9-10-26(11-17(15)32-21(19)24-12-23-20)33(30,31)18-4-2-1-3-16(18)27(28)29/h1-8,12H,9-11H2,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510363
(CHEMBL4449174)Show SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(Cl)cc3F)c21 Show InChI InChI=1S/C21H15ClFN5O4S2/c22-12-5-6-15(14(23)9-12)26-20-19-13-7-8-27(10-17(13)33-21(19)25-11-24-20)34(31,32)18-4-2-1-3-16(18)28(29)30/h1-6,9,11H,7-8,10H2,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510365
(CHEMBL4536609)Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(F)cc3Br)c21 Show InChI InChI=1S/C21H14BrF3N4O2S2/c22-14-7-11(23)1-3-16(14)28-20-19-13-5-6-29(9-17(13)32-21(19)27-10-26-20)33(30,31)18-4-2-12(24)8-15(18)25/h1-4,7-8,10H,5-6,9H2,(H,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510416
(CHEMBL4589352)Show SMILES Fc1cc(Cl)ccc1Nc1ncnc2sc3CN(Cc4ccccc4)CCc3c12 Show InChI InChI=1S/C22H18ClFN4S/c23-15-6-7-18(17(24)10-15)27-21-20-16-8-9-28(11-14-4-2-1-3-5-14)12-19(16)29-22(20)26-13-25-21/h1-7,10,13H,8-9,11-12H2,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510399
(CHEMBL4531356)Show SMILES COc1cc(F)ccc1Nc1ncnc2sc3CN(CCc3c12)C(=O)OC(C)(C)C Show InChI InChI=1S/C21H23FN4O3S/c1-21(2,3)29-20(27)26-8-7-13-16(10-26)30-19-17(13)18(23-11-24-19)25-14-6-5-12(22)9-15(14)28-4/h5-6,9,11H,7-8,10H2,1-4H3,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510375
(CHEMBL4561883)Show SMILES Fc1cc(Cl)ccc1Nc1ncnc2sc3CN(CCc3c12)S(=O)(=O)c1cccs1 Show InChI InChI=1S/C19H14ClFN4O2S3/c20-11-3-4-14(13(21)8-11)24-18-17-12-5-6-25(30(26,27)16-2-1-7-28-16)9-15(12)29-19(17)23-10-22-18/h1-4,7-8,10H,5-6,9H2,(H,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510378
(CHEMBL4575025)Show SMILES Clc1cccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2cccs2)c1 Show InChI InChI=1S/C19H15ClN4O2S3/c20-12-3-1-4-13(9-12)23-18-17-14-6-7-24(29(25,26)16-5-2-8-27-16)10-15(14)28-19(17)22-11-21-18/h1-5,8-9,11H,6-7,10H2,(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510435
(CHEMBL4446384)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3cccc(F)c3)c21 Show InChI InChI=1S/C22H19FN4O3S2/c1-30-16-5-7-17(8-6-16)32(28,29)27-10-9-18-19(12-27)31-22-20(18)21(24-13-25-22)26-15-4-2-3-14(23)11-15/h2-8,11,13H,9-10,12H2,1H3,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510441
(CHEMBL4563436)Show SMILES Brc1ccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2cccs2)cc1 Show InChI InChI=1S/C19H15BrN4O2S3/c20-12-3-5-13(6-4-12)23-18-17-14-7-8-24(29(25,26)16-2-1-9-27-16)10-15(14)28-19(17)22-11-21-18/h1-6,9,11H,7-8,10H2,(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510389
(CHEMBL4470343)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3cccc(Cl)c3)c21 Show InChI InChI=1S/C22H19ClN4O3S2/c1-30-16-5-7-17(8-6-16)32(28,29)27-10-9-18-19(12-27)31-22-20(18)21(24-13-25-22)26-15-4-2-3-14(23)11-15/h2-8,11,13H,9-10,12H2,1H3,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510387
(CHEMBL4581903)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3cccc(C)c3)c21 Show InChI InChI=1S/C23H22N4O3S2/c1-15-4-3-5-16(12-15)26-22-21-19-10-11-27(13-20(19)31-23(21)25-14-24-22)32(28,29)18-8-6-17(30-2)7-9-18/h3-9,12,14H,10-11,13H2,1-2H3,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510433
(CHEMBL4584574)Show SMILES Fc1ccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2cccs2)c(F)c1 Show InChI InChI=1S/C19H14F2N4O2S3/c20-11-3-4-14(13(21)8-11)24-18-17-12-5-6-25(30(26,27)16-2-1-7-28-16)9-15(12)29-19(17)23-10-22-18/h1-4,7-8,10H,5-6,9H2,(H,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510402
(CHEMBL4456947)Show InChI InChI=1S/C16H14BrFN4S/c1-22-5-4-10-13(7-22)23-16-14(10)15(19-8-20-16)21-12-3-2-9(18)6-11(12)17/h2-3,6,8H,4-5,7H2,1H3,(H,19,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510411
(CHEMBL4463661)Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(Cl)cc3)c21 Show InChI InChI=1S/C21H15ClF2N4O2S2/c22-12-1-4-14(5-2-12)27-20-19-15-7-8-28(10-17(15)31-21(19)26-11-25-20)32(29,30)18-6-3-13(23)9-16(18)24/h1-6,9,11H,7-8,10H2,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510418
(CHEMBL4475709)Show SMILES Fc1cccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2cccs2)c1 Show InChI InChI=1S/C19H15FN4O2S3/c20-12-3-1-4-13(9-12)23-18-17-14-6-7-24(29(25,26)16-5-2-8-27-16)10-15(14)28-19(17)22-11-21-18/h1-5,8-9,11H,6-7,10H2,(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510394
(CHEMBL4567764)Show InChI InChI=1S/C16H14BrN3S/c17-10-5-7-11(8-6-10)20-15-14-12-3-1-2-4-13(12)21-16(14)19-9-18-15/h5-9H,1-4H2,(H,18,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510405
(CHEMBL4582192)Show SMILES Clc1ccc(Nc2ncnc3sc4CN(Cc5ccccc5)CCc4c23)cc1 Show InChI InChI=1S/C22H19ClN4S/c23-16-6-8-17(9-7-16)26-21-20-18-10-11-27(12-15-4-2-1-3-5-15)13-19(18)28-22(20)25-14-24-21/h1-9,14H,10-13H2,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510380
(CHEMBL4474103)Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(Cl)cc3F)c21 Show InChI InChI=1S/C21H14ClF3N4O2S2/c22-11-1-3-16(14(24)7-11)28-20-19-13-5-6-29(9-17(13)32-21(19)27-10-26-20)33(30,31)18-4-2-12(23)8-15(18)25/h1-4,7-8,10H,5-6,9H2,(H,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510373
(CHEMBL4533038)Show SMILES Cc1ccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2cccs2)c(Br)c1 Show InChI InChI=1S/C20H17BrN4O2S3/c1-12-4-5-15(14(21)9-12)24-19-18-13-6-7-25(30(26,27)17-3-2-8-28-17)10-16(13)29-20(18)23-11-22-19/h2-5,8-9,11H,6-7,10H2,1H3,(H,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510408
(CHEMBL4552830)Show SMILES Cc1ccc(Nc2ncnc3sc4CN(Cc5ccccc5)CCc4c23)c(Br)c1 Show InChI InChI=1S/C23H21BrN4S/c1-15-7-8-19(18(24)11-15)27-22-21-17-9-10-28(12-16-5-3-2-4-6-16)13-20(17)29-23(21)26-14-25-22/h2-8,11,14H,9-10,12-13H2,1H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510391
(CHEMBL4544794)Show InChI InChI=1S/C16H14ClN3S/c17-10-5-7-11(8-6-10)20-15-14-12-3-1-2-4-13(12)21-16(14)19-9-18-15/h5-9H,1-4H2,(H,18,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510397
(CHEMBL4560334)Show SMILES CC(C)(C)OC(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(F)cc3F)c21 Show InChI InChI=1S/C20H20F2N4O2S/c1-20(2,3)28-19(27)26-7-6-12-15(9-26)29-18-16(12)17(23-10-24-18)25-14-5-4-11(21)8-13(14)22/h4-5,8,10H,6-7,9H2,1-3H3,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510377
(CHEMBL4588895)Show SMILES Clc1ccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2cccs2)cc1 Show InChI InChI=1S/C19H15ClN4O2S3/c20-12-3-5-13(6-4-12)23-18-17-14-7-8-24(29(25,26)16-2-1-9-27-16)10-15(14)28-19(17)22-11-21-18/h1-6,9,11H,7-8,10H2,(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510409
(CHEMBL4583540)Show SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3cccc(Cl)c3)c21 Show InChI InChI=1S/C21H16ClN5O4S2/c22-13-4-3-5-14(10-13)25-20-19-15-8-9-26(11-17(15)32-21(19)24-12-23-20)33(30,31)18-7-2-1-6-16(18)27(28)29/h1-7,10,12H,8-9,11H2,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510427
(CHEMBL4563521)Show InChI InChI=1S/C17H17BrN4S/c1-10-3-4-13(12(18)7-10)21-16-15-11-5-6-22(2)8-14(11)23-17(15)20-9-19-16/h3-4,7,9H,5-6,8H2,1-2H3,(H,19,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510390
(CHEMBL4439152)Show SMILES Cc1ccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2ccccc2[N+]([O-])=O)c(Br)c1 Show InChI InChI=1S/C22H18BrN5O4S2/c1-13-6-7-16(15(23)10-13)26-21-20-14-8-9-27(11-18(14)33-22(20)25-12-24-21)34(31,32)19-5-3-2-4-17(19)28(29)30/h2-7,10,12H,8-9,11H2,1H3,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510439
(CHEMBL4552946)Show SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(Cl)cc3)c21 Show InChI InChI=1S/C21H16ClN5O4S2/c22-13-5-7-14(8-6-13)25-20-19-15-9-10-26(11-17(15)32-21(19)24-12-23-20)33(30,31)18-4-2-1-3-16(18)27(28)29/h1-8,12H,9-11H2,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510379
(CHEMBL4452969)Show SMILES Cc1ccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2ccc(F)cc2F)c(Br)c1 Show InChI InChI=1S/C22H17BrF2N4O2S2/c1-12-2-4-17(15(23)8-12)28-21-20-14-6-7-29(10-18(14)32-22(20)27-11-26-21)33(30,31)19-5-3-13(24)9-16(19)25/h2-5,8-9,11H,6-7,10H2,1H3,(H,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510428
(CHEMBL4513266)Show SMILES Brc1ccc(Nc2ncnc3sc4CN(Cc5ccccc5)CCc4c23)cc1 Show InChI InChI=1S/C22H19BrN4S/c23-16-6-8-17(9-7-16)26-21-20-18-10-11-27(12-15-4-2-1-3-5-15)13-19(18)28-22(20)25-14-24-21/h1-9,14H,10-13H2,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510361
(CHEMBL4460480)Show InChI InChI=1S/C16H15BrN4S/c1-21-7-6-12-13(8-21)22-16-14(12)15(18-9-19-16)20-11-4-2-10(17)3-5-11/h2-5,9H,6-8H2,1H3,(H,18,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510423
(CHEMBL4577910)Show InChI InChI=1S/C17H17N3OS/c1-21-12-6-4-5-11(9-12)20-16-15-13-7-2-3-8-14(13)22-17(15)19-10-18-16/h4-6,9-10H,2-3,7-8H2,1H3,(H,18,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510400
(CHEMBL4447312)Show SMILES Cc1ccc(Nc2ncnc3sc4CN(CCc4c23)C(=O)OC(C)(C)C)c(Br)c1 Show InChI InChI=1S/C21H23BrN4O2S/c1-12-5-6-15(14(22)9-12)25-18-17-13-7-8-26(20(27)28-21(2,3)4)10-16(13)29-19(17)24-11-23-18/h5-6,9,11H,7-8,10H2,1-4H3,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510398
(CHEMBL4560849)Show SMILES CC(C)(C)OC(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(F)cc3Br)c21 Show InChI InChI=1S/C20H20BrFN4O2S/c1-20(2,3)28-19(27)26-7-6-12-15(9-26)29-18-16(12)17(23-10-24-18)25-14-5-4-11(22)8-13(14)21/h4-5,8,10H,6-7,9H2,1-3H3,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510381
(CHEMBL4549130)Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(Br)cc3)c21 Show InChI InChI=1S/C21H15BrF2N4O2S2/c22-12-1-4-14(5-2-12)27-20-19-15-7-8-28(10-17(15)31-21(19)26-11-25-20)32(29,30)18-6-3-13(23)9-16(18)24/h1-6,9,11H,7-8,10H2,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510383
(CHEMBL4482949)Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3cccc(Cl)c3)c21 Show InChI InChI=1S/C21H15ClF2N4O2S2/c22-12-2-1-3-14(8-12)27-20-19-15-6-7-28(10-17(15)31-21(19)26-11-25-20)32(29,30)18-5-4-13(23)9-16(18)24/h1-5,8-9,11H,6-7,10H2,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510413
(CHEMBL4577564)Show InChI InChI=1S/C17H17N3S/c1-11-5-4-6-12(9-11)20-16-15-13-7-2-3-8-14(13)21-17(15)19-10-18-16/h4-6,9-10H,2-3,7-8H2,1H3,(H,18,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510414
(CHEMBL4565804)Show SMILES CC(C)(C)OC(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(Br)cc3)c21 Show InChI InChI=1S/C20H21BrN4O2S/c1-20(2,3)27-19(26)25-9-8-14-15(10-25)28-18-16(14)17(22-11-23-18)24-13-6-4-12(21)5-7-13/h4-7,11H,8-10H2,1-3H3,(H,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510372
(CHEMBL4453419)Show InChI InChI=1S/C16H15ClN4S/c1-21-7-6-12-13(8-21)22-16-14(12)15(18-9-19-16)20-11-4-2-10(17)3-5-11/h2-5,9H,6-8H2,1H3,(H,18,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510437
(CHEMBL4547308)Show InChI InChI=1S/C16H14ClFN4S/c1-22-5-4-10-13(7-22)23-16-14(10)15(19-8-20-16)21-12-3-2-9(17)6-11(12)18/h2-3,6,8H,4-5,7H2,1H3,(H,19,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510415
(CHEMBL4471478)Show InChI InChI=1S/C16H15ClN4S/c1-21-6-5-12-13(8-21)22-16-14(12)15(18-9-19-16)20-11-4-2-3-10(17)7-11/h2-4,7,9H,5-6,8H2,1H3,(H,18,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510434
(CHEMBL4445835)Show SMILES COc1cccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C22H18F2N4O3S2/c1-31-15-4-2-3-14(10-15)27-21-20-16-7-8-28(11-18(16)32-22(20)26-12-25-21)33(29,30)19-6-5-13(23)9-17(19)24/h2-6,9-10,12H,7-8,11H2,1H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510384
(CHEMBL4553042)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(C)cc3Br)c21 Show InChI InChI=1S/C23H21BrN4O3S2/c1-14-3-8-19(18(24)11-14)27-22-21-17-9-10-28(12-20(17)32-23(21)26-13-25-22)33(29,30)16-6-4-15(31-2)5-7-16/h3-8,11,13H,9-10,12H2,1-2H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510406
(CHEMBL4538136)Show SMILES COc1cccc(Nc2ncnc3sc4CN(Cc5ccccc5)CCc4c23)c1 Show InChI InChI=1S/C23H22N4OS/c1-28-18-9-5-8-17(12-18)26-22-21-19-10-11-27(13-16-6-3-2-4-7-16)14-20(19)29-23(21)25-15-24-22/h2-9,12,15H,10-11,13-14H2,1H3,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510424
(CHEMBL4580707)Show SMILES COc1cccc(Nc2ncnc3sc4CN(CCc4c23)C(=O)OC(C)(C)C)c1 Show InChI InChI=1S/C21H24N4O3S/c1-21(2,3)28-20(26)25-9-8-15-16(11-25)29-19-17(15)18(22-12-23-19)24-13-6-5-7-14(10-13)27-4/h5-7,10,12H,8-9,11H2,1-4H3,(H,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510438
(CHEMBL4458291)Show SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3cccc(F)c3)c21 Show InChI InChI=1S/C21H16FN5O4S2/c22-13-4-3-5-14(10-13)25-20-19-15-8-9-26(11-17(15)32-21(19)24-12-23-20)33(30,31)18-7-2-1-6-16(18)27(28)29/h1-7,10,12H,8-9,11H2,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510420
(CHEMBL4436762)Show SMILES Fc1cccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C21H15F3N4O2S2/c22-12-2-1-3-14(8-12)27-20-19-15-6-7-28(10-17(15)31-21(19)26-11-25-20)32(29,30)18-5-4-13(23)9-16(18)24/h1-5,8-9,11H,6-7,10H2,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510430
(CHEMBL4465305)Show SMILES COc1cccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2ccccc2[N+]([O-])=O)c1 Show InChI InChI=1S/C22H19N5O5S2/c1-32-15-6-4-5-14(11-15)25-21-20-16-9-10-26(12-18(16)33-22(20)24-13-23-21)34(30,31)19-8-3-2-7-17(19)27(28)29/h2-8,11,13H,9-10,12H2,1H3,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510401
(CHEMBL4464820)Show InChI InChI=1S/C16H15FN4S/c1-21-6-5-12-13(8-21)22-16-14(12)15(18-9-19-16)20-11-4-2-3-10(17)7-11/h2-4,7,9H,5-6,8H2,1H3,(H,18,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510368
(CHEMBL4541427)Show SMILES Cc1cccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2ccccc2[N+]([O-])=O)c1 Show InChI InChI=1S/C22H19N5O4S2/c1-14-5-4-6-15(11-14)25-21-20-16-9-10-26(12-18(16)32-22(20)24-13-23-21)33(30,31)19-8-3-2-7-17(19)27(28)29/h2-8,11,13H,9-10,12H2,1H3,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510440
(CHEMBL4528911)Show InChI InChI=1S/C22H19FN4S/c23-16-7-4-8-17(11-16)26-21-20-18-9-10-27(12-15-5-2-1-3-6-15)13-19(18)28-22(20)25-14-24-21/h1-8,11,14H,9-10,12-13H2,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510362
(CHEMBL4462520)Show InChI InChI=1S/C23H22N4S/c1-16-6-5-9-18(12-16)26-22-21-19-10-11-27(13-17-7-3-2-4-8-17)14-20(19)28-23(21)25-15-24-22/h2-9,12,15H,10-11,13-14H2,1H3,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510417
(CHEMBL4565825)Show SMILES Cc1cccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2cccs2)c1 Show InChI InChI=1S/C20H18N4O2S3/c1-13-4-2-5-14(10-13)23-19-18-15-7-8-24(29(25,26)17-6-3-9-27-17)11-16(15)28-20(18)22-12-21-19/h2-6,9-10,12H,7-8,11H2,1H3,(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510388
(CHEMBL4468342)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2c(C1)sc1ncnc(Nc3cccc(OC)c3)c21 Show InChI InChI=1S/C23H22N4O4S2/c1-30-16-6-8-18(9-7-16)33(28,29)27-11-10-19-20(13-27)32-23-21(19)22(24-14-25-23)26-15-4-3-5-17(12-15)31-2/h3-9,12,14H,10-11,13H2,1-2H3,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510425
(CHEMBL4435681)Show SMILES CC(C)(C)OC(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(Cl)cc3F)c21 Show InChI InChI=1S/C20H20ClFN4O2S/c1-20(2,3)28-19(27)26-7-6-12-15(9-26)29-18-16(12)17(23-10-24-18)25-14-5-4-11(21)8-13(14)22/h4-5,8,10H,6-7,9H2,1-3H3,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510436
(CHEMBL4578472)Show SMILES CC(C)(C)OC(=O)N1CCc2c(C1)sc1ncnc(Nc3cccc(Cl)c3)c21 Show InChI InChI=1S/C20H21ClN4O2S/c1-20(2,3)27-19(26)25-8-7-14-15(10-25)28-18-16(14)17(22-11-23-18)24-13-6-4-5-12(21)9-13/h4-6,9,11H,7-8,10H2,1-3H3,(H,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510393
(CHEMBL4453264)Show InChI InChI=1S/C16H14FN3S/c17-10-4-3-5-11(8-10)20-15-14-12-6-1-2-7-13(12)21-16(14)19-9-18-15/h3-5,8-9H,1-2,6-7H2,(H,18,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510395
(CHEMBL4584161)Show SMILES CC(C)(C)OC(=O)N1CCc2c(C1)sc1ncnc(Nc3cccc(F)c3)c21 Show InChI InChI=1S/C20H21FN4O2S/c1-20(2,3)27-19(26)25-8-7-14-15(10-25)28-18-16(14)17(22-11-23-18)24-13-6-4-5-12(21)9-13/h4-6,9,11H,7-8,10H2,1-3H3,(H,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510431
(CHEMBL4452434)Show InChI InChI=1S/C17H18N4S/c1-11-4-3-5-12(8-11)20-16-15-13-6-7-21(2)9-14(13)22-17(15)19-10-18-16/h3-5,8,10H,6-7,9H2,1-2H3,(H,18,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510360
(CHEMBL4579676)Show SMILES CC(C)(C)OC(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(Cl)cc3)c21 Show InChI InChI=1S/C20H21ClN4O2S/c1-20(2,3)27-19(26)25-9-8-14-15(10-25)28-18-16(14)17(22-11-23-18)24-13-6-4-12(21)5-7-13/h4-7,11H,8-10H2,1-3H3,(H,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510404
(CHEMBL4519701)Show SMILES Clc1cccc(Nc2ncnc3sc4CN(Cc5ccccc5)CCc4c23)c1 Show InChI InChI=1S/C22H19ClN4S/c23-16-7-4-8-17(11-16)26-21-20-18-9-10-27(12-15-5-2-1-3-6-15)13-19(18)28-22(20)25-14-24-21/h1-8,11,14H,9-10,12-13H2,(H,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510371
(CHEMBL4471970)Show InChI InChI=1S/C17H18N4OS/c1-21-7-6-13-14(9-21)23-17-15(13)16(18-10-19-17)20-11-4-3-5-12(8-11)22-2/h3-5,8,10H,6-7,9H2,1-2H3,(H,18,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510376
(CHEMBL4557048)Show SMILES COc1cccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2cccs2)c1 Show InChI InChI=1S/C20H18N4O3S3/c1-27-14-5-2-4-13(10-14)23-19-18-15-7-8-24(30(25,26)17-6-3-9-28-17)11-16(15)29-20(18)22-12-21-19/h2-6,9-10,12H,7-8,11H2,1H3,(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510382
(CHEMBL4533624)Show SMILES Cc1cccc(Nc2ncnc3sc4CN(CCc4c23)S(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C22H18F2N4O2S2/c1-13-3-2-4-15(9-13)27-21-20-16-7-8-28(11-18(16)31-22(20)26-12-25-21)32(29,30)19-6-5-14(23)10-17(19)24/h2-6,9-10,12H,7-8,11H2,1H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510392
(CHEMBL4474849)Show InChI InChI=1S/C16H14ClN3S/c17-10-4-3-5-11(8-10)20-15-14-12-6-1-2-7-13(12)21-16(14)19-9-18-15/h3-5,8-9H,1-2,6-7H2,(H,18,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50510396
(CHEMBL4568118)Show SMILES Cc1cccc(Nc2ncnc3sc4CN(CCc4c23)C(=O)OC(C)(C)C)c1 Show InChI InChI=1S/C21H24N4O2S/c1-13-6-5-7-14(10-13)24-18-17-15-8-9-25(20(26)27-21(2,3)4)11-16(15)28-19(17)23-12-22-18/h5-7,10,12H,8-9,11H2,1-4H3,(H,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50130693
(CGP-57380 | CHEMBL1240885)Show InChI InChI=1S/C11H9FN6/c12-6-1-3-7(4-2-6)16-11-8-9(13)14-5-15-10(8)17-18-11/h1-5H,(H4,13,14,15,16,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chengdu Medical College
Curated by ChEMBL
| Assay Description
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay |
Bioorg Med Chem 27: 2268-2279 (2019)
Article DOI: 10.1016/j.bmc.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V2Z |
More data for this
Ligand-Target Pair | |
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