Affinity Data by PubMed id=3361583

PubMed code 3361583

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM50405683 (CHEMBL174909) Show SMILES CCCCN1C(=O)C2CC2(C1=O)c1ccc(N)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Apparent inhibition constant (Ki) for cytochrome P450 19A1 with androstenedione				J Med Chem 31: 971-6 (1988) BindingDB Entry DOI: 10.7270/Q2154J7X
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50011767 (1-(4-Amino-phenyl)-3-pentyl-3-aza-bicyclo[3.1.0]he...) Show SMILES CCCCCN1C(=O)C2CC2(C1=O)c1ccc(N)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 androstenedione				J Med Chem 31: 971-6 (1988) BindingDB Entry DOI: 10.7270/Q2154J7X
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50405688 (CHEMBL174407) Show SMILES CCCN1C(=O)C2CC2(C1=O)c1ccc(N)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 androstenedione				J Med Chem 31: 971-6 (1988) BindingDB Entry DOI: 10.7270/Q2154J7X
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50011760 (1-(4-Amino-phenyl)-3-aza-bicyclo[3.1.0]hexane-2,4-...) Show SMILES Nc1ccc(cc1)C12CC1C(=O)NC2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 androstenedione				J Med Chem 31: 971-6 (1988) BindingDB Entry DOI: 10.7270/Q2154J7X
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9460 (3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione \| 3...) Show SMILES CCC1(CCC(=O)NC1=O)c1ccc(N)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 with testosterone				J Med Chem 31: 971-6 (1988) BindingDB Entry DOI: 10.7270/Q2154J7X
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%