Affinity Data by PubMed id=3950907

PubMed code 3950907

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 \|c:4\| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of guinea pig phosphodiesterase type III				J Med Chem 29: 261-7 (1986) BindingDB Entry DOI: 10.7270/Q2B56MZQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226149 (CHEMBL315111) Show SMILES Cn1cc(nc1-c1ccccc1)C1=NNC(=O)CC1 \|t:14\| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of guinea pig phosphodiesterase type III				J Med Chem 29: 261-7 (1986) BindingDB Entry DOI: 10.7270/Q2B56MZQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226152 (CHEMBL314150) Show SMILES Cn1c(cnc1-c1ccccc1)C1=NNC(=O)CC1 \|t:14\| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of guinea pig phosphodiesterase type III				J Med Chem 29: 261-7 (1986) BindingDB Entry DOI: 10.7270/Q2B56MZQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226148 (CHEMBL89955) Show SMILES COc1ccc(cc1OC)-c1nc(cn1C)-c1ccc(O)nn1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of guinea pig phosphodiesterase type III				J Med Chem 29: 261-7 (1986) BindingDB Entry DOI: 10.7270/Q2B56MZQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226151 (CHEMBL89048) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of guinea pig phosphodiesterase type III				J Med Chem 29: 261-7 (1986) BindingDB Entry DOI: 10.7270/Q2B56MZQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226150 (CHEMBL312938) Show SMILES Cn1c(cnc1-c1ccccc1)-c1ccc(O)nn1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of guinea pig phosphodiesterase type III				J Med Chem 29: 261-7 (1986) BindingDB Entry DOI: 10.7270/Q2B56MZQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%