Affinity Data by PubMed id=3950911

PubMed code 3950911

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dopamine beta-hydroxylase (Bos taurus)	BDBM50026182 (3-Phenyl-prop-2-ynylamine \| CHEMBL110611 \| US91619...) Show SMILES NCC#Cc1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was determined for the kinetic constant against Dopamine beta hydroxylase purified from beef adrenals, inhibitory constant (Ki)				J Med Chem 29: 315-7 (1986) BindingDB Entry DOI: 10.7270/Q2H99464
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Bos taurus)	BDBM50023370 (2-Thiophen-2-yl-allylamine \| CHEMBL110604) Show SMILES NCC(=C)c1cccs1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was determined for the kinetic constant against Dopamine beta hydroxylase purified from beef adrenals, inhibitory constant (Ki)				J Med Chem 29: 315-7 (1986) BindingDB Entry DOI: 10.7270/Q2H99464
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Bos taurus)	BDBM50026184 (2-Furan-3-yl-allylamine \| CHEMBL108927) Show SMILES NCC(=C)c1ccoc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was determined for the kinetic constant against Dopamine beta hydroxylase purified from beef adrenals, inhibitory constant (Ki)				J Med Chem 29: 315-7 (1986) BindingDB Entry DOI: 10.7270/Q2H99464
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Bos taurus)	BDBM50026189 (1-Methyl-2-thiophen-2-yl-allylamine \| CHEMBL325080) Show SMILES CC(N)C(=C)c1cccs1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was determined for the kinetic constant against Dopamine beta hydroxylase purified from beef adrenals, inhibitory constant (Ki)				J Med Chem 29: 315-7 (1986) BindingDB Entry DOI: 10.7270/Q2H99464
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Bos taurus)	BDBM50026187 (2-Furan-2-yl-allylamine \| CHEMBL106238) Show SMILES NCC(=C)c1ccco1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	4.10E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was determined for the kinetic constant against Dopamine beta hydroxylase purified from beef adrenals, inhibitory constant (Ki)				J Med Chem 29: 315-7 (1986) BindingDB Entry DOI: 10.7270/Q2H99464
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Bos taurus)	BDBM50026183 (2-Thiophen-3-yl-allylamine \| CHEMBL108921) Show SMILES NCC(=C)c1ccsc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	5.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was determined for the kinetic constant against Dopamine beta hydroxylase purified from beef adrenals, inhibitory constant (Ki)				J Med Chem 29: 315-7 (1986) BindingDB Entry DOI: 10.7270/Q2H99464
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Bos taurus)	BDBM50026186 (CHEMBL106130 \| Methyl-(2-thiophen-2-yl-allyl)-amin...) Show SMILES CNCC(=C)c1cccs1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.15E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was determined for the kinetic constant against Dopamine beta hydroxylase purified from beef adrenals, inhibitory constant (Ki)				J Med Chem 29: 315-7 (1986) BindingDB Entry DOI: 10.7270/Q2H99464
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Bos taurus)	BDBM50026188 (2-Phenyl-allylamine \| CHEMBL89394) Show SMILES NCC(=C)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was determined for the kinetic constant against Dopamine beta hydroxylase purified from beef adrenals, inhibitory constant (Ki)				J Med Chem 29: 315-7 (1986) BindingDB Entry DOI: 10.7270/Q2H99464
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Bos taurus)	BDBM50026185 (CHEMBL105998 \| Prop-1-ynyl-benzene) Show SMILES CC#Cc1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	2.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was determined for the kinetic constant against Dopamine beta hydroxylase purified from beef adrenals, inhibitory constant (Ki)				J Med Chem 29: 315-7 (1986) BindingDB Entry DOI: 10.7270/Q2H99464
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%