Affinity Data by PubMed id=8182712

PubMed code 8182712

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50041604 (3-(4-Chloro-phenyl)-8-((E)-3-iodo-allyl)-8-aza-bic...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22165 (1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50041603 (3-(4-Chloro-phenyl)-8-((Z)-3-iodo-allyl)-8-aza-bic...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50041604 (3-(4-Chloro-phenyl)-8-((E)-3-iodo-allyl)-8-aza-bic...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-13 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50041603 (3-(4-Chloro-phenyl)-8-((Z)-3-iodo-allyl)-8-aza-bic...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-13 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22165 (1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-13 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-13 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22416 ((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	642	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-13 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) Show SMILES CNCCCN1c2ccccc2CCc2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE \| 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	6.03E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%