Affinity Data by PubMed id=8917654

PubMed code 8917654

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2 (RAT-Rattus norvegicus (Rat))	BDBM50048855 (3-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-4H-imidazo...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-4513 from alpha6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranes				J Med Chem 39: 4654-66 (1996) Article DOI: 10.1021/jm960401i BindingDB Entry DOI: 10.7270/Q20K27NN
Upjohn Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2 (RAT-Rattus norvegicus (Rat))	BDBM50054660 (8-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-4,5-dihydr...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-4513 from alpha6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranes				J Med Chem 39: 4654-66 (1996) Article DOI: 10.1021/jm960401i BindingDB Entry DOI: 10.7270/Q20K27NN
Upjohn Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2 (RAT-Rattus norvegicus (Rat))	BDBM50054662 (8-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-4,4-dimeth...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-4513 from alpha6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranes				J Med Chem 39: 4654-66 (1996) Article DOI: 10.1021/jm960401i BindingDB Entry DOI: 10.7270/Q20K27NN
Upjohn Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2 (RAT-Rattus norvegicus (Rat))	BDBM50054663 (7-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-4-methoxy-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-4513 from alpha6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranes				J Med Chem 39: 4654-66 (1996) Article DOI: 10.1021/jm960401i BindingDB Entry DOI: 10.7270/Q20K27NN
Upjohn Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2 (RAT-Rattus norvegicus (Rat))	BDBM50054659 (8-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-4H,7H-5-ox...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-4513 from alpha6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranes				J Med Chem 39: 4654-66 (1996) Article DOI: 10.1021/jm960401i BindingDB Entry DOI: 10.7270/Q20K27NN
Upjohn Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2 (RAT-Rattus norvegicus (Rat))	BDBM50054656 (8-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-5-isopropy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-4513 from alpha6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranes				J Med Chem 39: 4654-66 (1996) Article DOI: 10.1021/jm960401i BindingDB Entry DOI: 10.7270/Q20K27NN
Upjohn Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2 (RAT-Rattus norvegicus (Rat))	BDBM50054661 (8-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-5-methyl-4...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-4513 from alpha6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranes				J Med Chem 39: 4654-66 (1996) Article DOI: 10.1021/jm960401i BindingDB Entry DOI: 10.7270/Q20K27NN
Upjohn Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%