Found 30 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glucagon receptor
(Rattus norvegicus) | BDBM50098571
(CHEMBL266481 | GLUCAGON | His-Ser-Gln-Gly-Thr-Phe-...)Show SMILES CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O Show InChI InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059352
(CHEMBL442499 | [des-His1, Trp6, Glu9] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C150H222N42O47S/c1-70(2)53-97(133(224)174-96(48-52-240-11)132(223)182-104(60-113(156)205)142(233)191-119(74(8)197)122(157)213)177-137(228)102(58-80-63-164-87-27-17-15-25-84(80)87)181-130(221)94(42-46-112(155)204)175-146(237)118(72(5)6)190-140(231)101(55-77-23-13-12-14-24-77)180-138(229)105(61-116(209)210)183-129(220)93(41-45-111(154)203)168-123(214)73(7)167-126(217)90(30-21-50-162-149(158)159)170-127(218)91(31-22-51-163-150(160)161)172-144(235)108(68-195)187-139(230)106(62-117(211)212)184-134(225)98(54-71(3)4)176-135(226)99(56-78-32-36-82(200)37-33-78)178-128(219)89(29-19-20-49-151)171-143(234)107(67-194)186-136(227)100(57-79-34-38-83(201)39-35-79)179-131(222)95(43-47-115(207)208)173-145(236)109(69-196)188-148(239)121(76(10)199)192-141(232)103(59-81-64-165-88-28-18-16-26-85(81)88)185-147(238)120(75(9)198)189-114(206)65-166-125(216)92(40-44-110(153)202)169-124(215)86(152)66-193/h12-18,23-28,32-39,63-64,70-76,86,89-109,118-121,164-165,193-201H,19-22,29-31,40-62,65-69,151-152H2,1-11H3,(H2,153,202)(H2,154,203)(H2,155,204)(H2,156,205)(H2,157,213)(H,166,216)(H,167,217)(H,168,214)(H,169,215)(H,170,218)(H,171,234)(H,172,235)(H,173,236)(H,174,224)(H,175,237)(H,176,226)(H,177,228)(H,178,219)(H,179,222)(H,180,229)(H,181,221)(H,182,223)(H,183,220)(H,184,225)(H,185,238)(H,186,227)(H,187,230)(H,188,239)(H,189,206)(H,190,231)(H,191,233)(H,192,232)(H,207,208)(H,209,210)(H,211,212)(H4,158,159,162)(H4,160,161,163)/t73-,74+,75+,76+,86-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,118-,119-,120-,121-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059358
(CHEMBL267885 | [des-His1, Tyr6,Glu9] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C148H221N41O48S/c1-69(2)53-95(131(222)171-94(48-52-238-11)130(221)179-102(60-111(154)203)140(231)188-117(73(8)194)120(155)211)174-135(226)101(59-80-63-162-86-24-16-15-23-84(80)86)178-128(219)92(42-46-110(153)202)172-144(235)116(71(5)6)187-138(229)99(55-76-21-13-12-14-22-76)177-136(227)103(61-114(207)208)180-127(218)91(41-45-109(152)201)165-121(212)72(7)164-124(215)88(26-19-50-160-147(156)157)167-125(216)89(27-20-51-161-148(158)159)169-142(233)106(67-192)184-137(228)104(62-115(209)210)181-132(223)96(54-70(3)4)173-133(224)97(56-77-28-34-81(197)35-29-77)175-126(217)87(25-17-18-49-149)168-141(232)105(66-191)183-134(225)98(57-78-30-36-82(198)37-31-78)176-129(220)93(43-47-113(205)206)170-143(234)107(68-193)185-146(237)119(75(10)196)189-139(230)100(58-79-32-38-83(199)39-33-79)182-145(236)118(74(9)195)186-112(204)64-163-123(214)90(40-44-108(151)200)166-122(213)85(150)65-190/h12-16,21-24,28-39,63,69-75,85,87-107,116-119,162,190-199H,17-20,25-27,40-62,64-68,149-150H2,1-11H3,(H2,151,200)(H2,152,201)(H2,153,202)(H2,154,203)(H2,155,211)(H,163,214)(H,164,215)(H,165,212)(H,166,213)(H,167,216)(H,168,232)(H,169,233)(H,170,234)(H,171,222)(H,172,235)(H,173,224)(H,174,226)(H,175,217)(H,176,220)(H,177,227)(H,178,219)(H,179,221)(H,180,218)(H,181,223)(H,182,236)(H,183,225)(H,184,228)(H,185,237)(H,186,204)(H,187,229)(H,188,231)(H,189,230)(H,205,206)(H,207,208)(H,209,210)(H4,156,157,160)(H4,158,159,161)/t72-,73+,74+,75+,85-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,116-,117-,118-,119-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059356
(CHEMBL2369990 | [des-His1, Nle6, Glu9] glucagon-NH...)Show SMILES CCCCC(NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@H](CO)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CO)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](C)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C148H221N41O47S/c1-70(2)54-95(131(221)171-94(49-53-237-11)130(220)179-102(61-111(154)202)140(230)188-117(74(8)194)120(155)210)174-135(225)101(60-81-64-162-86-29-19-18-28-84(81)86)178-128(218)92(43-47-110(153)201)172-144(234)116(72(5)6)187-138(228)99(56-77-24-14-12-15-25-77)177-136(226)103(62-114(206)207)180-127(217)91(42-46-109(152)200)165-121(211)73(7)164-124(214)88(31-22-51-160-147(156)157)167-125(215)89(32-23-52-161-148(158)159)169-142(232)106(68-192)184-137(227)104(63-115(208)209)181-132(222)96(55-71(3)4)173-133(223)97(58-79-33-37-82(197)38-34-79)175-126(216)87(30-20-21-50-149)168-141(231)105(67-191)183-134(224)98(59-80-35-39-83(198)40-36-80)176-129(219)93(44-48-113(204)205)170-143(233)107(69-193)185-146(236)119(76(10)196)189-139(229)100(57-78-26-16-13-17-27-78)182-145(235)118(75(9)195)186-112(203)65-163-123(213)90(41-45-108(151)199)166-122(212)85(150)66-190/h12-19,24-29,33-40,64,70-76,85,87-107,116-119,162,190-198H,20-23,30-32,41-63,65-69,149-150H2,1-11H3,(H2,151,199)(H2,152,200)(H2,153,201)(H2,154,202)(H2,155,210)(H,163,213)(H,164,214)(H,165,211)(H,166,212)(H,167,215)(H,168,231)(H,169,232)(H,170,233)(H,171,221)(H,172,234)(H,173,223)(H,174,225)(H,175,216)(H,176,219)(H,177,226)(H,178,218)(H,179,220)(H,180,217)(H,181,222)(H,182,235)(H,183,224)(H,184,227)(H,185,236)(H,186,203)(H,187,228)(H,188,230)(H,189,229)(H,204,205)(H,206,207)(H,208,209)(H4,156,157,160)(H4,158,159,161)/t73-,74+,75+,76+,85-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100+,101-,102-,103-,104-,105-,106-,107-,116-,117-,118-,119-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059362
(CHEMBL268636 | [des-His1, des-Phe6, Glu9] glucagon...)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C139H212N40O46S/c1-64(2)49-88(123(211)162-87(44-48-226-11)122(210)170-94(55-103(145)192)131(219)178-109(68(8)184)112(146)200)165-127(215)93(54-74-58-153-79-24-16-15-23-77(74)79)169-120(208)85(38-42-102(144)191)163-135(223)108(66(5)6)177-130(218)92(51-71-21-13-12-14-22-71)168-128(216)95(56-106(196)197)171-119(207)84(37-41-101(143)190)156-113(201)67(7)155-116(204)81(26-19-46-151-138(147)148)158-117(205)82(27-20-47-152-139(149)150)160-133(221)98(62-182)174-129(217)96(57-107(198)199)172-124(212)89(50-65(3)4)164-125(213)90(52-72-28-32-75(187)33-29-72)166-118(206)80(25-17-18-45-140)159-132(220)97(61-181)173-126(214)91(53-73-30-34-76(188)35-31-73)167-121(209)86(39-43-105(194)195)161-134(222)99(63-183)175-136(224)111(70(10)186)179-137(225)110(69(9)185)176-104(193)59-154-115(203)83(36-40-100(142)189)157-114(202)78(141)60-180/h12-16,21-24,28-35,58,64-70,78,80-99,108-111,153,180-188H,17-20,25-27,36-57,59-63,140-141H2,1-11H3,(H2,142,189)(H2,143,190)(H2,144,191)(H2,145,192)(H2,146,200)(H,154,203)(H,155,204)(H,156,201)(H,157,202)(H,158,205)(H,159,220)(H,160,221)(H,161,222)(H,162,211)(H,163,223)(H,164,213)(H,165,215)(H,166,206)(H,167,209)(H,168,216)(H,169,208)(H,170,210)(H,171,207)(H,172,212)(H,173,214)(H,174,217)(H,175,224)(H,176,193)(H,177,218)(H,178,219)(H,179,225)(H,194,195)(H,196,197)(H,198,199)(H4,147,148,151)(H4,149,150,152)/t67-,68+,69+,70+,78-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,108-,109-,110-,111-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059359
(CHEMBL411289 | [des-His1, des-Gly4, Glu9] glucagon...)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C146H218N40O46S/c1-69(2)54-94(129(217)168-93(49-53-233-11)127(215)176-101(61-110(152)199)138(226)184-115(73(8)191)118(153)206)171-133(221)100(60-80-64-160-85-29-19-18-28-83(80)85)175-125(213)90(42-46-108(150)197)169-142(230)114(71(5)6)183-136(224)98(56-76-24-14-12-15-25-76)174-134(222)102(62-112(202)203)177-124(212)89(41-45-107(149)196)162-119(207)72(7)161-121(209)87(31-22-51-158-145(154)155)164-122(210)88(32-23-52-159-146(156)157)166-140(228)105(67-189)181-135(223)103(63-113(204)205)178-130(218)95(55-70(3)4)170-131(219)96(58-78-33-37-81(194)38-34-78)172-123(211)86(30-20-21-50-147)165-139(227)104(66-188)180-132(220)97(59-79-35-39-82(195)40-36-79)173-126(214)92(44-48-111(200)201)167-141(229)106(68-190)182-144(232)117(75(10)193)186-137(225)99(57-77-26-16-13-17-27-77)179-143(231)116(74(9)192)185-128(216)91(43-47-109(151)198)163-120(208)84(148)65-187/h12-19,24-29,33-40,64,69-75,84,86-106,114-117,160,187-195H,20-23,30-32,41-63,65-68,147-148H2,1-11H3,(H2,149,196)(H2,150,197)(H2,151,198)(H2,152,199)(H2,153,206)(H,161,209)(H,162,207)(H,163,208)(H,164,210)(H,165,227)(H,166,228)(H,167,229)(H,168,217)(H,169,230)(H,170,219)(H,171,221)(H,172,211)(H,173,214)(H,174,222)(H,175,213)(H,176,215)(H,177,212)(H,178,218)(H,179,231)(H,180,220)(H,181,223)(H,182,232)(H,183,224)(H,184,226)(H,185,216)(H,186,225)(H,200,201)(H,202,203)(H,204,205)(H4,154,155,158)(H4,156,157,159)/t72-,73+,74+,75+,84-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,114-,115-,116-,117-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059364
(CHEMBL2369985 | [des-His1, D-Phe6, Glu9] glucagon-...)Show SMILES CCCC[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@H](CO)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CO)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](C)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O |wU:42.41,112.113,219.223,189.191,162.163,57.56,96.97,203.207,180.182,145.146,75.75,129.130,29.30,36.37,228.234,wD:35.34,227.231,69.69,4.4,173.175,104.105,154.155,16.21,84.84,8.8,48.47,211.215,118.119,25.25,140.142,(86.13,-.36,;84.69,-.91,;84.45,-2.43,;83.01,-2.97,;82.76,-4.49,;83.95,-5.47,;85.39,-4.92,;85.64,-3.4,;86.59,-5.89,;88.03,-5.35,;89.22,-6.32,;88.97,-7.84,;90.66,-5.77,;91.85,-6.75,;93.29,-6.2,;93.54,-4.68,;94.49,-7.18,;94.24,-8.7,;95.43,-9.67,;95.18,-11.19,;96.38,-12.16,;93.75,-11.74,;95.93,-6.63,;97.12,-7.6,;96.87,-9.12,;98.56,-7.06,;98.81,-5.54,;99.75,-8.03,;101.19,-7.48,;86.34,-7.41,;84.9,-7.96,;87.53,-8.39,;81.32,-5.04,;81.07,-6.56,;80.13,-4.06,;78.69,-4.61,;78.44,-6.13,;77,-6.68,;79.63,-7.1,;77.5,-3.64,;77.74,-2.12,;76.06,-4.18,;74.86,-3.21,;75.11,-1.69,;76.55,-1.14,;73.42,-3.76,;73.18,-5.28,;72.23,-2.78,;70.79,-3.33,;70.54,-4.85,;71.74,-5.82,;71.49,-7.34,;70.05,-7.89,;72.68,-8.32,;69.6,-2.35,;70.69,-1.27,;68.16,-2.9,;66.96,-1.93,;67.21,-.41,;68.65,.14,;69.84,-.83,;71.28,-.29,;71.53,1.23,;72.97,1.78,;70.34,2.21,;68.9,1.66,;65.52,-2.47,;65.28,-3.99,;64.33,-1.5,;62.89,-2.05,;62.64,-3.57,;61.2,-4.11,;61.7,-1.07,;61.94,.45,;60.26,-1.62,;59.07,-.64,;59.31,.88,;58.12,1.85,;58.37,3.37,;57.17,4.34,;57.42,5.86,;57.63,-1.19,;57.38,-2.71,;56.43,-.22,;54.99,-.76,;54.75,-2.28,;53.31,-2.83,;52.11,-1.86,;50.67,-2.4,;50.43,-3.92,;48.99,-4.47,;51.62,-4.9,;53.06,-4.35,;53.8,.21,;54.05,1.73,;52.36,-.34,;51.17,.64,;51.41,2.16,;50.22,3.13,;48.78,2.59,;50.47,4.65,;49.73,.09,;49.48,-1.43,;48.53,1.07,;47.09,.52,;46.85,-1,;45.41,-1.55,;45.16,-3.07,;44.21,-.57,;45.9,1.49,;46.15,3.01,;44.46,.95,;43.27,1.92,;43.51,3.44,;42.32,4.41,;41.83,1.37,;41.58,-.15,;40.64,2.35,;39.2,1.8,;38.95,.28,;37.51,-.26,;37.26,-1.78,;35.82,-2.33,;35.57,-3.85,;36.77,-4.82,;34.14,-4.4,;38,2.78,;38.25,4.3,;36.56,2.23,;35.37,3.2,;35.62,4.72,;37.06,5.27,;37.3,6.79,;38.74,7.34,;38.99,8.86,;37.8,9.83,;40.43,9.4,;33.93,2.66,;33.68,1.14,;32.74,3.63,;31.3,3.08,;31.05,1.56,;30.1,4.06,;30.35,5.58,;28.66,3.51,;27.47,4.49,;27.72,6.01,;26.52,6.98,;26.77,8.5,;28.21,9.05,;25.58,9.47,;26.03,3.94,;25.78,2.42,;24.84,4.91,;23.4,4.37,;23.15,2.85,;24.34,1.87,;24.1,.35,;25.83,1.47,;22.2,5.34,;22.45,6.86,;20.77,4.79,;19.57,5.77,;19.82,7.29,;18.63,8.26,;17.19,7.72,;15.99,8.69,;16.24,10.21,;17.68,10.76,;18.87,9.78,;18.13,5.22,;17.89,3.7,;16.94,6.2,;15.5,5.65,;15.25,4.13,;16.45,3.16,;13.81,3.58,;14.31,6.62,;14.55,8.14,;12.87,6.08,;11.67,7.05,;11.92,8.57,;10.73,9.55,;10.97,11.07,;12.41,11.61,;9.78,12.04,;10.23,6.5,;9.99,4.98,;9.04,7.48,;7.6,6.93,;6.41,7.91,;6.65,9.43,;8.03,10.12,;7.79,11.64,;6.27,11.89,;5.44,13.18,;3.9,13.11,;3.2,11.74,;4.03,10.44,;5.57,10.52,;7.35,5.41,;5.91,4.87,;8.55,4.44,;8.3,2.92,;6.86,2.37,;6.61,.85,;7.81,-.12,;5.17,.31,;9.49,1.94,;10.93,2.49,;9.25,.42,;10.44,-.55,;11.88,-0,;13.07,-.98,;14.51,-.43,;15.71,-1.4,;10.19,-2.07,;8.75,-2.62,;11.39,-3.04,;11.14,-4.56,;9.7,-5.11,;9.45,-6.63,;8.01,-7.18,;10.65,-7.6,;12.33,-5.54,;13.77,-4.99,;12.08,-7.06,;13.28,-8.03,;14.72,-7.48,;15.91,-8.46,;14.96,-5.96,;13.03,-9.55,;11.59,-10.1,;14.22,-10.53,)| Show InChI InChI=1S/C145H223N41O47S/c1-13-14-27-84(169-142(232)115(73(10)192)183-109(200)63-160-120(210)88(40-44-105(148)196)163-119(209)82(147)64-187)128(218)186-116(74(11)193)143(233)182-104(67-190)140(230)167-91(43-47-110(201)202)126(216)174-96(57-77-34-38-80(195)39-35-77)132(222)180-102(65-188)138(228)165-85(29-20-21-49-146)123(213)173-95(56-76-32-36-79(194)37-33-76)131(221)171-94(54-69(4)5)130(220)179-101(61-112(205)206)135(225)181-103(66-189)139(229)166-87(31-23-51-158-145(155)156)122(212)164-86(30-22-50-157-144(153)154)121(211)161-71(8)118(208)162-89(41-45-106(149)197)124(214)178-100(60-111(203)204)134(224)175-97(55-75-24-16-15-17-25-75)136(226)184-113(70(6)7)141(231)170-90(42-46-107(150)198)125(215)176-98(58-78-62-159-83-28-19-18-26-81(78)83)133(223)172-93(53-68(2)3)129(219)168-92(48-52-234-12)127(217)177-99(59-108(151)199)137(227)185-114(72(9)191)117(152)207/h15-19,24-26,28,32-39,62,68-74,82,84-104,113-116,159,187-195H,13-14,20-23,27,29-31,40-61,63-67,146-147H2,1-12H3,(H2,148,196)(H2,149,197)(H2,150,198)(H2,151,199)(H2,152,207)(H,160,210)(H,161,211)(H,162,208)(H,163,209)(H,164,212)(H,165,228)(H,166,229)(H,167,230)(H,168,219)(H,169,232)(H,170,231)(H,171,221)(H,172,223)(H,173,213)(H,174,216)(H,175,224)(H,176,215)(H,177,217)(H,178,214)(H,179,220)(H,180,222)(H,181,225)(H,182,233)(H,183,200)(H,184,226)(H,185,227)(H,186,218)(H,201,202)(H,203,204)(H,205,206)(H4,153,154,157)(H4,155,156,158)/t71-,72+,73+,74+,82-,84+,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,113-,114-,115-,116-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059365
(CHEMBL412352 | [des-Phe6, Glu9] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)Cc1c[nH]cn1)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C145H219N43O47S/c1-67(2)49-92(128(220)170-91(44-48-236-11)127(219)178-98(56-108(151)201)136(228)187-114(71(8)193)117(152)209)173-132(224)97(54-77-59-160-83-24-16-15-23-81(77)83)177-125(217)89(38-42-107(150)200)171-141(233)113(69(5)6)186-135(227)96(51-74-21-13-12-14-22-74)176-133(225)99(57-111(205)206)179-124(216)88(37-41-106(149)199)164-118(210)70(7)163-121(213)85(26-19-46-158-144(153)154)165-122(214)86(27-20-47-159-145(155)156)167-139(231)103(64-191)183-134(226)100(58-112(207)208)180-129(221)93(50-68(3)4)172-130(222)94(52-75-28-32-79(196)33-29-75)174-123(215)84(25-17-18-45-146)166-138(230)102(63-190)182-131(223)95(53-76-30-34-80(197)35-31-76)175-126(218)90(39-43-110(203)204)169-140(232)104(65-192)184-142(234)116(73(10)195)188-143(235)115(72(9)194)185-109(202)61-161-120(212)87(36-40-105(148)198)168-137(229)101(62-189)181-119(211)82(147)55-78-60-157-66-162-78/h12-16,21-24,28-35,59-60,66-73,82,84-104,113-116,160,189-197H,17-20,25-27,36-58,61-65,146-147H2,1-11H3,(H2,148,198)(H2,149,199)(H2,150,200)(H2,151,201)(H2,152,209)(H,157,162)(H,161,212)(H,163,213)(H,164,210)(H,165,214)(H,166,230)(H,167,231)(H,168,229)(H,169,232)(H,170,220)(H,171,233)(H,172,222)(H,173,224)(H,174,215)(H,175,218)(H,176,225)(H,177,217)(H,178,219)(H,179,216)(H,180,221)(H,181,211)(H,182,223)(H,183,226)(H,184,234)(H,185,202)(H,186,227)(H,187,228)(H,188,235)(H,203,204)(H,205,206)(H,207,208)(H4,153,154,158)(H4,155,156,159)/t70-,71+,72+,73+,82-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,113-,114-,115-,116-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 113 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059363
(CHEMBL437095 | [des-His1,Ala6, Glu9] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@@H](C)NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C142H217N41O47S/c1-65(2)50-90(126(216)166-89(45-49-231-12)125(215)174-96(56-105(148)196)134(224)182-111(70(9)188)114(149)204)169-130(220)95(55-76-59-156-81-25-17-16-24-79(76)81)173-123(213)87(39-43-104(147)195)167-138(228)110(67(5)6)181-133(223)94(52-73-22-14-13-15-23-73)172-131(221)97(57-108(200)201)175-122(212)86(38-42-103(146)194)160-115(205)68(7)158-119(209)83(27-20-47-154-141(150)151)162-120(210)84(28-21-48-155-142(152)153)164-136(226)100(63-186)178-132(222)98(58-109(202)203)176-127(217)91(51-66(3)4)168-128(218)92(53-74-29-33-77(191)34-30-74)170-121(211)82(26-18-19-46-143)163-135(225)99(62-185)177-129(219)93(54-75-31-35-78(192)36-32-75)171-124(214)88(40-44-107(198)199)165-137(227)101(64-187)179-140(230)113(72(11)190)183-116(206)69(8)159-139(229)112(71(10)189)180-106(197)60-157-118(208)85(37-41-102(145)193)161-117(207)80(144)61-184/h13-17,22-25,29-36,59,65-72,80,82-101,110-113,156,184-192H,18-21,26-28,37-58,60-64,143-144H2,1-12H3,(H2,145,193)(H2,146,194)(H2,147,195)(H2,148,196)(H2,149,204)(H,157,208)(H,158,209)(H,159,229)(H,160,205)(H,161,207)(H,162,210)(H,163,225)(H,164,226)(H,165,227)(H,166,216)(H,167,228)(H,168,218)(H,169,220)(H,170,211)(H,171,214)(H,172,221)(H,173,213)(H,174,215)(H,175,212)(H,176,217)(H,177,219)(H,178,222)(H,179,230)(H,180,197)(H,181,223)(H,182,224)(H,183,206)(H,198,199)(H,200,201)(H,202,203)(H4,150,151,154)(H4,152,153,155)/t68-,69-,70+,71+,72+,80-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,110-,111-,112-,113-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059360
(CHEMBL429198 | [des-His1, des-Phe6] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C138H210N40O46S/c1-63(2)47-86(121(209)160-85(42-46-225-11)120(208)168-92(53-102(144)191)130(218)177-108(67(8)183)111(145)199)163-125(213)91(52-73-57-152-78-24-16-15-23-76(73)78)167-119(207)84(38-41-101(143)190)161-134(222)107(65(5)6)176-129(217)90(49-70-21-13-12-14-22-70)166-126(214)93(54-104(193)194)169-118(206)83(37-40-100(142)189)155-112(200)66(7)154-115(203)80(26-19-44-150-137(146)147)157-116(204)81(27-20-45-151-138(148)149)159-132(220)97(61-181)173-128(216)95(56-106(197)198)170-122(210)87(48-64(3)4)162-123(211)88(50-71-28-32-74(186)33-29-71)164-117(205)79(25-17-18-43-139)158-131(219)96(60-180)172-124(212)89(51-72-30-34-75(187)35-31-72)165-127(215)94(55-105(195)196)171-133(221)98(62-182)174-135(223)110(69(10)185)178-136(224)109(68(9)184)175-103(192)58-153-114(202)82(36-39-99(141)188)156-113(201)77(140)59-179/h12-16,21-24,28-35,57,63-69,77,79-98,107-110,152,179-187H,17-20,25-27,36-56,58-62,139-140H2,1-11H3,(H2,141,188)(H2,142,189)(H2,143,190)(H2,144,191)(H2,145,199)(H,153,202)(H,154,203)(H,155,200)(H,156,201)(H,157,204)(H,158,219)(H,159,220)(H,160,209)(H,161,222)(H,162,211)(H,163,213)(H,164,205)(H,165,215)(H,166,214)(H,167,207)(H,168,208)(H,169,206)(H,170,210)(H,171,221)(H,172,212)(H,173,216)(H,174,223)(H,175,192)(H,176,217)(H,177,218)(H,178,224)(H,193,194)(H,195,196)(H,197,198)(H4,146,147,150)(H4,148,149,151)/t66-,67+,68+,69+,77-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,107-,108-,109-,110-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059361
(CHEMBL439271 | [des-His1, des-Phe6] glucagon)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(O)=O Show InChI InChI=1S/C138H209N39O47S/c1-63(2)47-86(120(207)159-85(42-46-225-11)119(206)167-92(53-102(144)190)129(216)177-110(69(10)184)136(223)224)162-124(211)91(52-73-57-151-78-24-16-15-23-76(73)78)166-118(205)84(38-41-101(143)189)160-133(220)107(65(5)6)175-128(215)90(49-70-21-13-12-14-22-70)165-125(212)93(54-104(192)193)168-117(204)83(37-40-100(142)188)154-111(198)66(7)153-114(201)80(26-19-44-149-137(145)146)156-115(202)81(27-20-45-150-138(147)148)158-131(218)97(61-180)172-127(214)95(56-106(196)197)169-121(208)87(48-64(3)4)161-122(209)88(50-71-28-32-74(185)33-29-71)163-116(203)79(25-17-18-43-139)157-130(217)96(60-179)171-123(210)89(51-72-30-34-75(186)35-31-72)164-126(213)94(55-105(194)195)170-132(219)98(62-181)173-134(221)109(68(9)183)176-135(222)108(67(8)182)174-103(191)58-152-113(200)82(36-39-99(141)187)155-112(199)77(140)59-178/h12-16,21-24,28-35,57,63-69,77,79-98,107-110,151,178-186H,17-20,25-27,36-56,58-62,139-140H2,1-11H3,(H2,141,187)(H2,142,188)(H2,143,189)(H2,144,190)(H,152,200)(H,153,201)(H,154,198)(H,155,199)(H,156,202)(H,157,217)(H,158,218)(H,159,207)(H,160,220)(H,161,209)(H,162,211)(H,163,203)(H,164,213)(H,165,212)(H,166,205)(H,167,206)(H,168,204)(H,169,208)(H,170,219)(H,171,210)(H,172,214)(H,173,221)(H,174,191)(H,175,215)(H,176,222)(H,177,216)(H,192,193)(H,194,195)(H,196,197)(H,223,224)(H4,145,146,149)(H4,147,148,150)/t66-,67+,68+,69+,77-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,107-,108-,109-,110-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059355
(CHEMBL409611 | [des-Phe6] glucagon)Show SMILES CC(C)C[C@@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)Cc1cnc[nH]1)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CCS)C(=O)N[C@H](CC(N)=O)C(=O)N[C@@H](C=O)[C@H](C)O Show InChI InChI=1S/C143H214N42O47S/c1-66(2)46-90(125(216)166-89(41-45-233)124(215)174-96(53-108(149)199)130(221)178-100(60-186)70(8)191)169-129(220)95(51-76-57-157-82-23-15-14-22-80(76)82)173-123(214)88(37-40-107(148)198)167-139(230)113(68(5)6)184-134(225)94(48-73-20-12-11-13-21-73)172-131(222)97(54-110(201)202)175-122(213)87(36-39-106(147)197)161-116(207)69(7)160-119(210)84(25-18-43-155-142(150)151)162-120(211)85(26-19-44-156-143(152)153)164-137(228)103(63-189)181-133(224)99(56-112(205)206)176-126(217)91(47-67(3)4)168-127(218)92(49-74-27-31-78(194)32-28-74)170-121(212)83(24-16-17-42-144)163-136(227)102(62-188)180-128(219)93(50-75-29-33-79(195)34-30-75)171-132(223)98(55-111(203)204)177-138(229)104(64-190)182-140(231)115(72(10)193)185-141(232)114(71(9)192)183-109(200)59-158-118(209)86(35-38-105(146)196)165-135(226)101(61-187)179-117(208)81(145)52-77-58-154-65-159-77/h11-15,20-23,27-34,57-58,60,65-72,81,83-104,113-115,157,187-195,233H,16-19,24-26,35-56,59,61-64,144-145H2,1-10H3,(H2,146,196)(H2,147,197)(H2,148,198)(H2,149,199)(H,154,159)(H,158,209)(H,160,210)(H,161,207)(H,162,211)(H,163,227)(H,164,228)(H,165,226)(H,166,216)(H,167,230)(H,168,218)(H,169,220)(H,170,212)(H,171,223)(H,172,222)(H,173,214)(H,174,215)(H,175,213)(H,176,217)(H,177,229)(H,178,221)(H,179,208)(H,180,219)(H,181,224)(H,182,231)(H,183,200)(H,184,225)(H,185,232)(H,201,202)(H,203,204)(H,205,206)(H4,150,151,155)(H4,152,153,156)/t69-,70+,71+,72+,81-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100+,101-,102-,103-,104-,113-,114-,115-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059354
(CHEMBL438574 | [des-Phe6] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)Cc1cnc[nH]1)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C144H217N43O47S/c1-66(2)47-90(126(218)168-89(42-46-235-11)125(217)176-96(54-107(150)200)135(227)186-113(70(8)192)116(151)208)171-130(222)95(52-76-58-159-82-24-16-15-23-80(76)82)175-124(216)88(38-41-106(149)199)169-140(232)112(68(5)6)185-134(226)94(49-73-21-13-12-14-22-73)174-131(223)97(55-109(202)203)177-123(215)87(37-40-105(148)198)163-117(209)69(7)162-120(212)84(26-19-44-157-143(152)153)164-121(213)85(27-20-45-158-144(154)155)166-138(230)102(63-190)182-133(225)99(57-111(206)207)178-127(219)91(48-67(3)4)170-128(220)92(50-74-28-32-78(195)33-29-74)172-122(214)83(25-17-18-43-145)165-137(229)101(62-189)181-129(221)93(51-75-30-34-79(196)35-31-75)173-132(224)98(56-110(204)205)179-139(231)103(64-191)183-141(233)115(72(10)194)187-142(234)114(71(9)193)184-108(201)60-160-119(211)86(36-39-104(147)197)167-136(228)100(61-188)180-118(210)81(146)53-77-59-156-65-161-77/h12-16,21-24,28-35,58-59,65-72,81,83-103,112-115,159,188-196H,17-20,25-27,36-57,60-64,145-146H2,1-11H3,(H2,147,197)(H2,148,198)(H2,149,199)(H2,150,200)(H2,151,208)(H,156,161)(H,160,211)(H,162,212)(H,163,209)(H,164,213)(H,165,229)(H,166,230)(H,167,228)(H,168,218)(H,169,232)(H,170,220)(H,171,222)(H,172,214)(H,173,224)(H,174,223)(H,175,216)(H,176,217)(H,177,215)(H,178,219)(H,179,231)(H,180,210)(H,181,221)(H,182,225)(H,183,233)(H,184,201)(H,185,226)(H,186,227)(H,187,234)(H,202,203)(H,204,205)(H,206,207)(H4,152,153,157)(H4,154,155,158)/t69-,70+,71+,72+,81-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,112-,113-,114-,115-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 512 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059351
(CHEMBL427744 | [des-His1, des-Phe6, Glu9] glucagon...)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(O)=O Show InChI InChI=1S/C139H211N39O47S/c1-64(2)49-88(122(209)161-87(44-48-226-11)121(208)169-94(55-103(145)191)130(217)178-111(70(10)185)137(224)225)164-126(213)93(54-74-58-152-79-24-16-15-23-77(74)79)168-119(206)85(38-42-102(144)190)162-134(221)108(66(5)6)176-129(216)92(51-71-21-13-12-14-22-71)167-127(214)95(56-106(195)196)170-118(205)84(37-41-101(143)189)155-112(199)67(7)154-115(202)81(26-19-46-150-138(146)147)157-116(203)82(27-20-47-151-139(148)149)159-132(219)98(62-181)173-128(215)96(57-107(197)198)171-123(210)89(50-65(3)4)163-124(211)90(52-72-28-32-75(186)33-29-72)165-117(204)80(25-17-18-45-140)158-131(218)97(61-180)172-125(212)91(53-73-30-34-76(187)35-31-73)166-120(207)86(39-43-105(193)194)160-133(220)99(63-182)174-135(222)110(69(9)184)177-136(223)109(68(8)183)175-104(192)59-153-114(201)83(36-40-100(142)188)156-113(200)78(141)60-179/h12-16,21-24,28-35,58,64-70,78,80-99,108-111,152,179-187H,17-20,25-27,36-57,59-63,140-141H2,1-11H3,(H2,142,188)(H2,143,189)(H2,144,190)(H2,145,191)(H,153,201)(H,154,202)(H,155,199)(H,156,200)(H,157,203)(H,158,218)(H,159,219)(H,160,220)(H,161,209)(H,162,221)(H,163,211)(H,164,213)(H,165,204)(H,166,207)(H,167,214)(H,168,206)(H,169,208)(H,170,205)(H,171,210)(H,172,212)(H,173,215)(H,174,222)(H,175,192)(H,176,216)(H,177,223)(H,178,217)(H,193,194)(H,195,196)(H,197,198)(H,224,225)(H4,146,147,150)(H4,148,149,151)/t67-,68+,69+,70+,78-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,108-,109-,110-,111-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059357
(CHEMBL438218 | [des-His1, Asp6, Glu9] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C143H217N41O49S/c1-65(2)49-89(126(218)166-88(44-48-234-11)125(217)174-95(55-105(149)197)134(226)183-112(69(8)189)115(150)207)169-130(222)94(54-75-59-157-80-24-16-15-23-78(75)80)173-123(215)86(38-42-104(148)196)167-139(231)111(67(5)6)182-133(225)93(51-72-21-13-12-14-22-72)172-131(223)96(56-108(201)202)175-122(214)85(37-41-103(147)195)160-116(208)68(7)159-119(211)82(26-19-46-155-142(151)152)162-120(212)83(27-20-47-156-143(153)154)164-137(229)100(63-187)179-132(224)97(57-109(203)204)176-127(219)90(50-66(3)4)168-128(220)91(52-73-28-32-76(192)33-29-73)170-121(213)81(25-17-18-45-144)163-136(228)99(62-186)178-129(221)92(53-74-30-34-77(193)35-31-74)171-124(216)87(39-43-107(199)200)165-138(230)101(64-188)180-141(233)114(71(10)191)184-135(227)98(58-110(205)206)177-140(232)113(70(9)190)181-106(198)60-158-118(210)84(36-40-102(146)194)161-117(209)79(145)61-185/h12-16,21-24,28-35,59,65-71,79,81-101,111-114,157,185-193H,17-20,25-27,36-58,60-64,144-145H2,1-11H3,(H2,146,194)(H2,147,195)(H2,148,196)(H2,149,197)(H2,150,207)(H,158,210)(H,159,211)(H,160,208)(H,161,209)(H,162,212)(H,163,228)(H,164,229)(H,165,230)(H,166,218)(H,167,231)(H,168,220)(H,169,222)(H,170,213)(H,171,216)(H,172,223)(H,173,215)(H,174,217)(H,175,214)(H,176,219)(H,177,232)(H,178,221)(H,179,224)(H,180,233)(H,181,198)(H,182,225)(H,183,226)(H,184,227)(H,199,200)(H,201,202)(H,203,204)(H,205,206)(H4,151,152,155)(H4,153,154,156)/t68-,69+,70+,71+,79-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,111-,112-,113-,114-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059351
(CHEMBL427744 | [des-His1, des-Phe6, Glu9] glucagon...)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(O)=O Show InChI InChI=1S/C139H211N39O47S/c1-64(2)49-88(122(209)161-87(44-48-226-11)121(208)169-94(55-103(145)191)130(217)178-111(70(10)185)137(224)225)164-126(213)93(54-74-58-152-79-24-16-15-23-77(74)79)168-119(206)85(38-42-102(144)190)162-134(221)108(66(5)6)176-129(216)92(51-71-21-13-12-14-22-71)167-127(214)95(56-106(195)196)170-118(205)84(37-41-101(143)189)155-112(199)67(7)154-115(202)81(26-19-46-150-138(146)147)157-116(203)82(27-20-47-151-139(148)149)159-132(219)98(62-181)173-128(215)96(57-107(197)198)171-123(210)89(50-65(3)4)163-124(211)90(52-72-28-32-75(186)33-29-72)165-117(204)80(25-17-18-45-140)158-131(218)97(61-180)172-125(212)91(53-73-30-34-76(187)35-31-73)166-120(207)86(39-43-105(193)194)160-133(220)99(63-182)174-135(222)110(69(9)184)177-136(223)109(68(8)183)175-104(192)59-153-114(201)83(36-40-100(142)188)156-113(200)78(141)60-179/h12-16,21-24,28-35,58,64-70,78,80-99,108-111,152,179-187H,17-20,25-27,36-57,59-63,140-141H2,1-11H3,(H2,142,188)(H2,143,189)(H2,144,190)(H2,145,191)(H,153,201)(H,154,202)(H,155,199)(H,156,200)(H,157,203)(H,158,218)(H,159,219)(H,160,220)(H,161,209)(H,162,221)(H,163,211)(H,164,213)(H,165,204)(H,166,207)(H,167,214)(H,168,206)(H,169,208)(H,170,205)(H,171,210)(H,172,212)(H,173,215)(H,174,222)(H,175,192)(H,176,216)(H,177,223)(H,178,217)(H,193,194)(H,195,196)(H,197,198)(H,224,225)(H4,146,147,150)(H4,148,149,151)/t67-,68+,69+,70+,78-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,108-,109-,110-,111-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagon |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059359
(CHEMBL411289 | [des-His1, des-Gly4, Glu9] glucagon...)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C146H218N40O46S/c1-69(2)54-94(129(217)168-93(49-53-233-11)127(215)176-101(61-110(152)199)138(226)184-115(73(8)191)118(153)206)171-133(221)100(60-80-64-160-85-29-19-18-28-83(80)85)175-125(213)90(42-46-108(150)197)169-142(230)114(71(5)6)183-136(224)98(56-76-24-14-12-15-25-76)174-134(222)102(62-112(202)203)177-124(212)89(41-45-107(149)196)162-119(207)72(7)161-121(209)87(31-22-51-158-145(154)155)164-122(210)88(32-23-52-159-146(156)157)166-140(228)105(67-189)181-135(223)103(63-113(204)205)178-130(218)95(55-70(3)4)170-131(219)96(58-78-33-37-81(194)38-34-78)172-123(211)86(30-20-21-50-147)165-139(227)104(66-188)180-132(220)97(59-79-35-39-82(195)40-36-79)173-126(214)92(44-48-111(200)201)167-141(229)106(68-190)182-144(232)117(75(10)193)186-137(225)99(57-77-26-16-13-17-27-77)179-143(231)116(74(9)192)185-128(216)91(43-47-109(151)198)163-120(208)84(148)65-187/h12-19,24-29,33-40,64,69-75,84,86-106,114-117,160,187-195H,20-23,30-32,41-63,65-68,147-148H2,1-11H3,(H2,149,196)(H2,150,197)(H2,151,198)(H2,152,199)(H2,153,206)(H,161,209)(H,162,207)(H,163,208)(H,164,210)(H,165,227)(H,166,228)(H,167,229)(H,168,217)(H,169,230)(H,170,219)(H,171,221)(H,172,211)(H,173,214)(H,174,222)(H,175,213)(H,176,215)(H,177,212)(H,178,218)(H,179,231)(H,180,220)(H,181,223)(H,182,232)(H,183,224)(H,184,226)(H,185,216)(H,186,225)(H,200,201)(H,202,203)(H,204,205)(H4,154,155,158)(H4,156,157,159)/t72-,73+,74+,75+,84-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,114-,115-,116-,117-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 891 | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
pA2 value against Glucagon Receptor |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059356
(CHEMBL2369990 | [des-His1, Nle6, Glu9] glucagon-NH...)Show SMILES CCCCC(NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@H](CO)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CO)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](C)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C148H221N41O47S/c1-70(2)54-95(131(221)171-94(49-53-237-11)130(220)179-102(61-111(154)202)140(230)188-117(74(8)194)120(155)210)174-135(225)101(60-81-64-162-86-29-19-18-28-84(81)86)178-128(218)92(43-47-110(153)201)172-144(234)116(72(5)6)187-138(228)99(56-77-24-14-12-15-25-77)177-136(226)103(62-114(206)207)180-127(217)91(42-46-109(152)200)165-121(211)73(7)164-124(214)88(31-22-51-160-147(156)157)167-125(215)89(32-23-52-161-148(158)159)169-142(232)106(68-192)184-137(227)104(63-115(208)209)181-132(222)96(55-71(3)4)173-133(223)97(58-79-33-37-82(197)38-34-79)175-126(216)87(30-20-21-50-149)168-141(231)105(67-191)183-134(224)98(59-80-35-39-83(198)40-36-80)176-129(219)93(44-48-113(204)205)170-143(233)107(69-193)185-146(236)119(76(10)196)189-139(229)100(57-78-26-16-13-17-27-78)182-145(235)118(75(9)195)186-112(203)65-163-123(213)90(41-45-108(151)199)166-122(212)85(150)66-190/h12-19,24-29,33-40,64,70-76,85,87-107,116-119,162,190-198H,20-23,30-32,41-63,65-69,149-150H2,1-11H3,(H2,151,199)(H2,152,200)(H2,153,201)(H2,154,202)(H2,155,210)(H,163,213)(H,164,214)(H,165,211)(H,166,212)(H,167,215)(H,168,231)(H,169,232)(H,170,233)(H,171,221)(H,172,234)(H,173,223)(H,174,225)(H,175,216)(H,176,219)(H,177,226)(H,178,218)(H,179,220)(H,180,217)(H,181,222)(H,182,235)(H,183,224)(H,184,227)(H,185,236)(H,186,203)(H,187,228)(H,188,230)(H,189,229)(H,204,205)(H,206,207)(H,208,209)(H4,156,157,160)(H4,158,159,161)/t73-,74+,75+,76+,85-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100+,101-,102-,103-,104-,105-,106-,107-,116-,117-,118-,119-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
pA2 value against Glucagon Receptor |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059361
(CHEMBL439271 | [des-His1, des-Phe6] glucagon)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(O)=O Show InChI InChI=1S/C138H209N39O47S/c1-63(2)47-86(120(207)159-85(42-46-225-11)119(206)167-92(53-102(144)190)129(216)177-110(69(10)184)136(223)224)162-124(211)91(52-73-57-151-78-24-16-15-23-76(73)78)166-118(205)84(38-41-101(143)189)160-133(220)107(65(5)6)175-128(215)90(49-70-21-13-12-14-22-70)165-125(212)93(54-104(192)193)168-117(204)83(37-40-100(142)188)154-111(198)66(7)153-114(201)80(26-19-44-149-137(145)146)156-115(202)81(27-20-45-150-138(147)148)158-131(218)97(61-180)172-127(214)95(56-106(196)197)169-121(208)87(48-64(3)4)161-122(209)88(50-71-28-32-74(185)33-29-71)163-116(203)79(25-17-18-43-139)157-130(217)96(60-179)171-123(210)89(51-72-30-34-75(186)35-31-72)164-126(213)94(55-105(194)195)170-132(219)98(62-181)173-134(221)109(68(9)183)176-135(222)108(67(8)182)174-103(191)58-152-113(200)82(36-39-99(141)187)155-112(199)77(140)59-178/h12-16,21-24,28-35,57,63-69,77,79-98,107-110,151,178-186H,17-20,25-27,36-56,58-62,139-140H2,1-11H3,(H2,141,187)(H2,142,188)(H2,143,189)(H2,144,190)(H,152,200)(H,153,201)(H,154,198)(H,155,199)(H,156,202)(H,157,217)(H,158,218)(H,159,207)(H,160,220)(H,161,209)(H,162,211)(H,163,203)(H,164,213)(H,165,212)(H,166,205)(H,167,206)(H,168,204)(H,169,208)(H,170,219)(H,171,210)(H,172,214)(H,173,221)(H,174,191)(H,175,215)(H,176,222)(H,177,216)(H,192,193)(H,194,195)(H,196,197)(H,223,224)(H4,145,146,149)(H4,147,148,150)/t66-,67+,68+,69+,77-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,107-,108-,109-,110-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 708 | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
pA2 value against Glucagon Receptor |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059360
(CHEMBL429198 | [des-His1, des-Phe6] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C138H210N40O46S/c1-63(2)47-86(121(209)160-85(42-46-225-11)120(208)168-92(53-102(144)191)130(218)177-108(67(8)183)111(145)199)163-125(213)91(52-73-57-152-78-24-16-15-23-76(73)78)167-119(207)84(38-41-101(143)190)161-134(222)107(65(5)6)176-129(217)90(49-70-21-13-12-14-22-70)166-126(214)93(54-104(193)194)169-118(206)83(37-40-100(142)189)155-112(200)66(7)154-115(203)80(26-19-44-150-137(146)147)157-116(204)81(27-20-45-151-138(148)149)159-132(220)97(61-181)173-128(216)95(56-106(197)198)170-122(210)87(48-64(3)4)162-123(211)88(50-71-28-32-74(186)33-29-71)164-117(205)79(25-17-18-43-139)158-131(219)96(60-180)172-124(212)89(51-72-30-34-75(187)35-31-72)165-127(215)94(55-105(195)196)171-133(221)98(62-182)174-135(223)110(69(10)185)178-136(224)109(68(9)184)175-103(192)58-153-114(202)82(36-39-99(141)188)156-113(201)77(140)59-179/h12-16,21-24,28-35,57,63-69,77,79-98,107-110,152,179-187H,17-20,25-27,36-56,58-62,139-140H2,1-11H3,(H2,141,188)(H2,142,189)(H2,143,190)(H2,144,191)(H2,145,199)(H,153,202)(H,154,203)(H,155,200)(H,156,201)(H,157,204)(H,158,219)(H,159,220)(H,160,209)(H,161,222)(H,162,211)(H,163,213)(H,164,205)(H,165,215)(H,166,214)(H,167,207)(H,168,208)(H,169,206)(H,170,210)(H,171,221)(H,172,212)(H,173,216)(H,174,223)(H,175,192)(H,176,217)(H,177,218)(H,178,224)(H,193,194)(H,195,196)(H,197,198)(H4,146,147,150)(H4,148,149,151)/t66-,67+,68+,69+,77-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,107-,108-,109-,110-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 562 | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
pA2 value against Glucagon Receptor |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059352
(CHEMBL442499 | [des-His1, Trp6, Glu9] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C150H222N42O47S/c1-70(2)53-97(133(224)174-96(48-52-240-11)132(223)182-104(60-113(156)205)142(233)191-119(74(8)197)122(157)213)177-137(228)102(58-80-63-164-87-27-17-15-25-84(80)87)181-130(221)94(42-46-112(155)204)175-146(237)118(72(5)6)190-140(231)101(55-77-23-13-12-14-24-77)180-138(229)105(61-116(209)210)183-129(220)93(41-45-111(154)203)168-123(214)73(7)167-126(217)90(30-21-50-162-149(158)159)170-127(218)91(31-22-51-163-150(160)161)172-144(235)108(68-195)187-139(230)106(62-117(211)212)184-134(225)98(54-71(3)4)176-135(226)99(56-78-32-36-82(200)37-33-78)178-128(219)89(29-19-20-49-151)171-143(234)107(67-194)186-136(227)100(57-79-34-38-83(201)39-35-79)179-131(222)95(43-47-115(207)208)173-145(236)109(69-196)188-148(239)121(76(10)199)192-141(232)103(59-81-64-165-88-28-18-16-26-85(81)88)185-147(238)120(75(9)198)189-114(206)65-166-125(216)92(40-44-110(153)202)169-124(215)86(152)66-193/h12-18,23-28,32-39,63-64,70-76,86,89-109,118-121,164-165,193-201H,19-22,29-31,40-62,65-69,151-152H2,1-11H3,(H2,153,202)(H2,154,203)(H2,155,204)(H2,156,205)(H2,157,213)(H,166,216)(H,167,217)(H,168,214)(H,169,215)(H,170,218)(H,171,234)(H,172,235)(H,173,236)(H,174,224)(H,175,237)(H,176,226)(H,177,228)(H,178,219)(H,179,222)(H,180,229)(H,181,221)(H,182,223)(H,183,220)(H,184,225)(H,185,238)(H,186,227)(H,187,230)(H,188,239)(H,189,206)(H,190,231)(H,191,233)(H,192,232)(H,207,208)(H,209,210)(H,211,212)(H4,158,159,162)(H4,160,161,163)/t73-,74+,75+,76+,86-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,118-,119-,120-,121-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 562 | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
pA2 value against Glucagon Receptor |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059351
(CHEMBL427744 | [des-His1, des-Phe6, Glu9] glucagon...)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(O)=O Show InChI InChI=1S/C139H211N39O47S/c1-64(2)49-88(122(209)161-87(44-48-226-11)121(208)169-94(55-103(145)191)130(217)178-111(70(10)185)137(224)225)164-126(213)93(54-74-58-152-79-24-16-15-23-77(74)79)168-119(206)85(38-42-102(144)190)162-134(221)108(66(5)6)176-129(216)92(51-71-21-13-12-14-22-71)167-127(214)95(56-106(195)196)170-118(205)84(37-41-101(143)189)155-112(199)67(7)154-115(202)81(26-19-46-150-138(146)147)157-116(203)82(27-20-47-151-139(148)149)159-132(219)98(62-181)173-128(215)96(57-107(197)198)171-123(210)89(50-65(3)4)163-124(211)90(52-72-28-32-75(186)33-29-72)165-117(204)80(25-17-18-45-140)158-131(218)97(61-180)172-125(212)91(53-73-30-34-76(187)35-31-73)166-120(207)86(39-43-105(193)194)160-133(220)99(63-182)174-135(222)110(69(9)184)177-136(223)109(68(8)183)175-104(192)59-153-114(201)83(36-40-100(142)188)156-113(200)78(141)60-179/h12-16,21-24,28-35,58,64-70,78,80-99,108-111,152,179-187H,17-20,25-27,36-57,59-63,140-141H2,1-11H3,(H2,142,188)(H2,143,189)(H2,144,190)(H2,145,191)(H,153,201)(H,154,202)(H,155,199)(H,156,200)(H,157,203)(H,158,218)(H,159,219)(H,160,220)(H,161,209)(H,162,221)(H,163,211)(H,164,213)(H,165,204)(H,166,207)(H,167,214)(H,168,206)(H,169,208)(H,170,205)(H,171,210)(H,172,212)(H,173,215)(H,174,222)(H,175,192)(H,176,216)(H,177,223)(H,178,217)(H,193,194)(H,195,196)(H,197,198)(H,224,225)(H4,146,147,150)(H4,148,149,151)/t67-,68+,69+,70+,78-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,108-,109-,110-,111-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
pA2 value against Glucagon Receptor |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059362
(CHEMBL268636 | [des-His1, des-Phe6, Glu9] glucagon...)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C139H212N40O46S/c1-64(2)49-88(123(211)162-87(44-48-226-11)122(210)170-94(55-103(145)192)131(219)178-109(68(8)184)112(146)200)165-127(215)93(54-74-58-153-79-24-16-15-23-77(74)79)169-120(208)85(38-42-102(144)191)163-135(223)108(66(5)6)177-130(218)92(51-71-21-13-12-14-22-71)168-128(216)95(56-106(196)197)171-119(207)84(37-41-101(143)190)156-113(201)67(7)155-116(204)81(26-19-46-151-138(147)148)158-117(205)82(27-20-47-152-139(149)150)160-133(221)98(62-182)174-129(217)96(57-107(198)199)172-124(212)89(50-65(3)4)164-125(213)90(52-72-28-32-75(187)33-29-72)166-118(206)80(25-17-18-45-140)159-132(220)97(61-181)173-126(214)91(53-73-30-34-76(188)35-31-73)167-121(209)86(39-43-105(194)195)161-134(222)99(63-183)175-136(224)111(70(10)186)179-137(225)110(69(9)185)176-104(193)59-154-115(203)83(36-40-100(142)189)157-114(202)78(141)60-180/h12-16,21-24,28-35,58,64-70,78,80-99,108-111,153,180-188H,17-20,25-27,36-57,59-63,140-141H2,1-11H3,(H2,142,189)(H2,143,190)(H2,144,191)(H2,145,192)(H2,146,200)(H,154,203)(H,155,204)(H,156,201)(H,157,202)(H,158,205)(H,159,220)(H,160,221)(H,161,222)(H,162,211)(H,163,223)(H,164,213)(H,165,215)(H,166,206)(H,167,209)(H,168,216)(H,169,208)(H,170,210)(H,171,207)(H,172,212)(H,173,214)(H,174,217)(H,175,224)(H,176,193)(H,177,218)(H,178,219)(H,179,225)(H,194,195)(H,196,197)(H,198,199)(H4,147,148,151)(H4,149,150,152)/t67-,68+,69+,70+,78-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,108-,109-,110-,111-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 6.31 | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
pA2 value against Glucagon Receptor |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50098571
(CHEMBL266481 | GLUCAGON | His-Ser-Gln-Gly-Thr-Phe-...)Show SMILES CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O Show InChI InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
cAMP accumulation in rat hepatocytes in the presence rolipram |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059365
(CHEMBL412352 | [des-Phe6, Glu9] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)Cc1c[nH]cn1)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C145H219N43O47S/c1-67(2)49-92(128(220)170-91(44-48-236-11)127(219)178-98(56-108(151)201)136(228)187-114(71(8)193)117(152)209)173-132(224)97(54-77-59-160-83-24-16-15-23-81(77)83)177-125(217)89(38-42-107(150)200)171-141(233)113(69(5)6)186-135(227)96(51-74-21-13-12-14-22-74)176-133(225)99(57-111(205)206)179-124(216)88(37-41-106(149)199)164-118(210)70(7)163-121(213)85(26-19-46-158-144(153)154)165-122(214)86(27-20-47-159-145(155)156)167-139(231)103(64-191)183-134(226)100(58-112(207)208)180-129(221)93(50-68(3)4)172-130(222)94(52-75-28-32-79(196)33-29-75)174-123(215)84(25-17-18-45-146)166-138(230)102(63-190)182-131(223)95(53-76-30-34-80(197)35-31-76)175-126(218)90(39-43-110(203)204)169-140(232)104(65-192)184-142(234)116(73(10)195)188-143(235)115(72(9)194)185-109(202)61-161-120(212)87(36-40-105(148)198)168-137(229)101(62-189)181-119(211)82(147)55-78-60-157-66-162-78/h12-16,21-24,28-35,59-60,66-73,82,84-104,113-116,160,189-197H,17-20,25-27,36-58,61-65,146-147H2,1-11H3,(H2,148,198)(H2,149,199)(H2,150,200)(H2,151,201)(H2,152,209)(H,157,162)(H,161,212)(H,163,213)(H,164,210)(H,165,214)(H,166,230)(H,167,231)(H,168,229)(H,169,232)(H,170,220)(H,171,233)(H,172,222)(H,173,224)(H,174,215)(H,175,218)(H,176,225)(H,177,217)(H,178,219)(H,179,216)(H,180,221)(H,181,211)(H,182,223)(H,183,226)(H,184,234)(H,185,202)(H,186,227)(H,187,228)(H,188,235)(H,203,204)(H,205,206)(H,207,208)(H4,153,154,158)(H4,155,156,159)/t70-,71+,72+,73+,82-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,113-,114-,115-,116-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
pA2 value against Glucagon Receptor |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059363
(CHEMBL437095 | [des-His1,Ala6, Glu9] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@@H](C)NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C142H217N41O47S/c1-65(2)50-90(126(216)166-89(45-49-231-12)125(215)174-96(56-105(148)196)134(224)182-111(70(9)188)114(149)204)169-130(220)95(55-76-59-156-81-25-17-16-24-79(76)81)173-123(213)87(39-43-104(147)195)167-138(228)110(67(5)6)181-133(223)94(52-73-22-14-13-15-23-73)172-131(221)97(57-108(200)201)175-122(212)86(38-42-103(146)194)160-115(205)68(7)158-119(209)83(27-20-47-154-141(150)151)162-120(210)84(28-21-48-155-142(152)153)164-136(226)100(63-186)178-132(222)98(58-109(202)203)176-127(217)91(51-66(3)4)168-128(218)92(53-74-29-33-77(191)34-30-74)170-121(211)82(26-18-19-46-143)163-135(225)99(62-185)177-129(219)93(54-75-31-35-78(192)36-32-75)171-124(214)88(40-44-107(198)199)165-137(227)101(64-187)179-140(230)113(72(11)190)183-116(206)69(8)159-139(229)112(71(10)189)180-106(197)60-157-118(208)85(37-41-102(145)193)161-117(207)80(144)61-184/h13-17,22-25,29-36,59,65-72,80,82-101,110-113,156,184-192H,18-21,26-28,37-58,60-64,143-144H2,1-12H3,(H2,145,193)(H2,146,194)(H2,147,195)(H2,148,196)(H2,149,204)(H,157,208)(H,158,209)(H,159,229)(H,160,205)(H,161,207)(H,162,210)(H,163,225)(H,164,226)(H,165,227)(H,166,216)(H,167,228)(H,168,218)(H,169,220)(H,170,211)(H,171,214)(H,172,221)(H,173,213)(H,174,215)(H,175,212)(H,176,217)(H,177,219)(H,178,222)(H,179,230)(H,180,197)(H,181,223)(H,182,224)(H,183,206)(H,198,199)(H,200,201)(H,202,203)(H4,150,151,154)(H4,152,153,155)/t68-,69-,70+,71+,72+,80-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,110-,111-,112-,113-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
pA2 value against Glucagon Receptor |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059355
(CHEMBL409611 | [des-Phe6] glucagon)Show SMILES CC(C)C[C@@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)Cc1cnc[nH]1)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CCS)C(=O)N[C@H](CC(N)=O)C(=O)N[C@@H](C=O)[C@H](C)O Show InChI InChI=1S/C143H214N42O47S/c1-66(2)46-90(125(216)166-89(41-45-233)124(215)174-96(53-108(149)199)130(221)178-100(60-186)70(8)191)169-129(220)95(51-76-57-157-82-23-15-14-22-80(76)82)173-123(214)88(37-40-107(148)198)167-139(230)113(68(5)6)184-134(225)94(48-73-20-12-11-13-21-73)172-131(222)97(54-110(201)202)175-122(213)87(36-39-106(147)197)161-116(207)69(7)160-119(210)84(25-18-43-155-142(150)151)162-120(211)85(26-19-44-156-143(152)153)164-137(228)103(63-189)181-133(224)99(56-112(205)206)176-126(217)91(47-67(3)4)168-127(218)92(49-74-27-31-78(194)32-28-74)170-121(212)83(24-16-17-42-144)163-136(227)102(62-188)180-128(219)93(50-75-29-33-79(195)34-30-75)171-132(223)98(55-111(203)204)177-138(229)104(64-190)182-140(231)115(72(10)193)185-141(232)114(71(9)192)183-109(200)59-158-118(209)86(35-38-105(146)196)165-135(226)101(61-187)179-117(208)81(145)52-77-58-154-65-159-77/h11-15,20-23,27-34,57-58,60,65-72,81,83-104,113-115,157,187-195,233H,16-19,24-26,35-56,59,61-64,144-145H2,1-10H3,(H2,146,196)(H2,147,197)(H2,148,198)(H2,149,199)(H,154,159)(H,158,209)(H,160,210)(H,161,207)(H,162,211)(H,163,227)(H,164,228)(H,165,226)(H,166,216)(H,167,230)(H,168,218)(H,169,220)(H,170,212)(H,171,223)(H,172,222)(H,173,214)(H,174,215)(H,175,213)(H,176,217)(H,177,229)(H,178,221)(H,179,208)(H,180,219)(H,181,224)(H,182,231)(H,183,200)(H,184,225)(H,185,232)(H,201,202)(H,203,204)(H,205,206)(H4,150,151,155)(H4,152,153,156)/t69-,70+,71+,72+,81-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100+,101-,102-,103-,104-,113-,114-,115-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 562 | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
pA2 value against Glucagon Receptor |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059358
(CHEMBL267885 | [des-His1, Tyr6,Glu9] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C148H221N41O48S/c1-69(2)53-95(131(222)171-94(48-52-238-11)130(221)179-102(60-111(154)203)140(231)188-117(73(8)194)120(155)211)174-135(226)101(59-80-63-162-86-24-16-15-23-84(80)86)178-128(219)92(42-46-110(153)202)172-144(235)116(71(5)6)187-138(229)99(55-76-21-13-12-14-22-76)177-136(227)103(61-114(207)208)180-127(218)91(41-45-109(152)201)165-121(212)72(7)164-124(215)88(26-19-50-160-147(156)157)167-125(216)89(27-20-51-161-148(158)159)169-142(233)106(67-192)184-137(228)104(62-115(209)210)181-132(223)96(54-70(3)4)173-133(224)97(56-77-28-34-81(197)35-29-77)175-126(217)87(25-17-18-49-149)168-141(232)105(66-191)183-134(225)98(57-78-30-36-82(198)37-31-78)176-129(220)93(43-47-113(205)206)170-143(234)107(68-193)185-146(237)119(75(10)196)189-139(230)100(58-79-32-38-83(199)39-33-79)182-145(236)118(74(9)195)186-112(204)64-163-123(214)90(40-44-108(151)200)166-122(213)85(150)65-190/h12-16,21-24,28-39,63,69-75,85,87-107,116-119,162,190-199H,17-20,25-27,40-62,64-68,149-150H2,1-11H3,(H2,151,200)(H2,152,201)(H2,153,202)(H2,154,203)(H2,155,211)(H,163,214)(H,164,215)(H,165,212)(H,166,213)(H,167,216)(H,168,232)(H,169,233)(H,170,234)(H,171,222)(H,172,235)(H,173,224)(H,174,226)(H,175,217)(H,176,220)(H,177,227)(H,178,219)(H,179,221)(H,180,218)(H,181,223)(H,182,236)(H,183,225)(H,184,228)(H,185,237)(H,186,204)(H,187,229)(H,188,231)(H,189,230)(H,205,206)(H,207,208)(H,209,210)(H4,156,157,160)(H4,158,159,161)/t72-,73+,74+,75+,85-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,116-,117-,118-,119-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
pA2 value against Glucagon Receptor |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059354
(CHEMBL438574 | [des-Phe6] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)Cc1cnc[nH]1)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C144H217N43O47S/c1-66(2)47-90(126(218)168-89(42-46-235-11)125(217)176-96(54-107(150)200)135(227)186-113(70(8)192)116(151)208)171-130(222)95(52-76-58-159-82-24-16-15-23-80(76)82)175-124(216)88(38-41-106(149)199)169-140(232)112(68(5)6)185-134(226)94(49-73-21-13-12-14-22-73)174-131(223)97(55-109(202)203)177-123(215)87(37-40-105(148)198)163-117(209)69(7)162-120(212)84(26-19-44-157-143(152)153)164-121(213)85(27-20-45-158-144(154)155)166-138(230)102(63-190)182-133(225)99(57-111(206)207)178-127(219)91(48-67(3)4)170-128(220)92(50-74-28-32-78(195)33-29-74)172-122(214)83(25-17-18-43-145)165-137(229)101(62-189)181-129(221)93(51-75-30-34-79(196)35-31-75)173-132(224)98(56-110(204)205)179-139(231)103(64-191)183-141(233)115(72(10)194)187-142(234)114(71(9)193)184-108(201)60-160-119(211)86(36-39-104(147)197)167-136(228)100(61-188)180-118(210)81(146)53-77-59-156-65-161-77/h12-16,21-24,28-35,58-59,65-72,81,83-103,112-115,159,188-196H,17-20,25-27,36-57,60-64,145-146H2,1-11H3,(H2,147,197)(H2,148,198)(H2,149,199)(H2,150,200)(H2,151,208)(H,156,161)(H,160,211)(H,162,212)(H,163,209)(H,164,213)(H,165,229)(H,166,230)(H,167,228)(H,168,218)(H,169,232)(H,170,220)(H,171,222)(H,172,214)(H,173,224)(H,174,223)(H,175,216)(H,176,217)(H,177,215)(H,178,219)(H,179,231)(H,180,210)(H,181,221)(H,182,225)(H,183,233)(H,184,201)(H,185,226)(H,186,227)(H,187,234)(H,202,203)(H,204,205)(H,206,207)(H4,152,153,157)(H4,154,155,158)/t69-,70+,71+,72+,81-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,112-,113-,114-,115-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
pA2 value against Glucagon Receptor |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Rattus norvegicus) | BDBM50059357
(CHEMBL438218 | [des-His1, Asp6, Glu9] glucagon-NH2)Show SMILES CSCC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CO)[C@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H]([C@H](C)O)C(N)=O Show InChI InChI=1S/C143H217N41O49S/c1-65(2)49-89(126(218)166-88(44-48-234-11)125(217)174-95(55-105(149)197)134(226)183-112(69(8)189)115(150)207)169-130(222)94(54-75-59-157-80-24-16-15-23-78(75)80)173-123(215)86(38-42-104(148)196)167-139(231)111(67(5)6)182-133(225)93(51-72-21-13-12-14-22-72)172-131(223)96(56-108(201)202)175-122(214)85(37-41-103(147)195)160-116(208)68(7)159-119(211)82(26-19-46-155-142(151)152)162-120(212)83(27-20-47-156-143(153)154)164-137(229)100(63-187)179-132(224)97(57-109(203)204)176-127(219)90(50-66(3)4)168-128(220)91(52-73-28-32-76(192)33-29-73)170-121(213)81(25-17-18-45-144)163-136(228)99(62-186)178-129(221)92(53-74-30-34-77(193)35-31-74)171-124(216)87(39-43-107(199)200)165-138(230)101(64-188)180-141(233)114(71(10)191)184-135(227)98(58-110(205)206)177-140(232)113(70(9)190)181-106(198)60-158-118(210)84(36-40-102(146)194)161-117(209)79(145)61-185/h12-16,21-24,28-35,59,65-71,79,81-101,111-114,157,185-193H,17-20,25-27,36-58,60-64,144-145H2,1-11H3,(H2,146,194)(H2,147,195)(H2,148,196)(H2,149,197)(H2,150,207)(H,158,210)(H,159,211)(H,160,208)(H,161,209)(H,162,212)(H,163,228)(H,164,229)(H,165,230)(H,166,218)(H,167,231)(H,168,220)(H,169,222)(H,170,213)(H,171,216)(H,172,223)(H,173,215)(H,174,217)(H,175,214)(H,176,219)(H,177,232)(H,178,221)(H,179,224)(H,180,233)(H,181,198)(H,182,225)(H,183,226)(H,184,227)(H,199,200)(H,201,202)(H,203,204)(H,205,206)(H4,151,152,155)(H4,153,154,156)/t68-,69+,70+,71+,79-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,111-,112-,113-,114-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
pA2 value against Glucagon Receptor |
J Med Chem 40: 2555-62 (1997)
Article DOI: 10.1021/jm960800d
BindingDB Entry DOI: 10.7270/Q2CC11CJ |
More data for this
Ligand-Target Pair | |
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