Affinity Data by PubMed id=9288168

PubMed code 9288168

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50059717 (4-(furan-3-yl)-7-((6-(4-hydroxytetrahydro-2H-pyran...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Compound was evaluated for the potency to inhibit oxidation of arachidonic acid by human recombinant 5-Lipoxygenase using a spectrophotometric assay				J Med Chem 40: 2866-75 (1997) Article DOI: 10.1021/jm970046b BindingDB Entry DOI: 10.7270/Q2QN67G4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50059715 (4-Furan-3-yl-7-[6-(3-hydroxy-6,8-dioxa-bicyclo[3.2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assay				J Med Chem 40: 2866-75 (1997) Article DOI: 10.1021/jm970046b BindingDB Entry DOI: 10.7270/Q2QN67G4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053554 (4-Furan-3-yl-7-[3-(4-hydroxy-tetrahydro-pyran-4-yl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assay				J Med Chem 40: 2866-75 (1997) Article DOI: 10.1021/jm970046b BindingDB Entry DOI: 10.7270/Q2QN67G4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50059722 (4-Furan-3-yl-7-[4-(4-hydroxy-tetrahydro-pyran-4-yl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assay				J Med Chem 40: 2866-75 (1997) Article DOI: 10.1021/jm970046b BindingDB Entry DOI: 10.7270/Q2QN67G4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50059720 (4-Furan-3-yl-7-[6-(3-hydroxy-6,8-dioxa-bicyclo[3.2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assay				J Med Chem 40: 2866-75 (1997) Article DOI: 10.1021/jm970046b BindingDB Entry DOI: 10.7270/Q2QN67G4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50059714 (4-Furan-3-yl-7-[5-(4-hydroxy-tetrahydro-pyran-4-yl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assay				J Med Chem 40: 2866-75 (1997) Article DOI: 10.1021/jm970046b BindingDB Entry DOI: 10.7270/Q2QN67G4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50059719 (4-Furan-3-yl-7-[2-(4-hydroxy-tetrahydro-pyran-4-yl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assay				J Med Chem 40: 2866-75 (1997) Article DOI: 10.1021/jm970046b BindingDB Entry DOI: 10.7270/Q2QN67G4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053548 (4-Furan-3-yl-7-[3-(3-hydroxy-6,8-dioxa-bicyclo[3.2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assay				J Med Chem 40: 2866-75 (1997) Article DOI: 10.1021/jm970046b BindingDB Entry DOI: 10.7270/Q2QN67G4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50059721 (4-Furan-3-yl-7-[2-(4-hydroxy-tetrahydro-pyran-4-yl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Compound was evaluated for the potency to inhibit oxidation of arachidonic acid by human recombinant 5-Lipoxygenase using a spectrophotometric assay				J Med Chem 40: 2866-75 (1997) Article DOI: 10.1021/jm970046b BindingDB Entry DOI: 10.7270/Q2QN67G4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50059718 (4-Furan-3-yl-7-[7-(4-hydroxy-tetrahydro-pyran-4-yl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assay				J Med Chem 40: 2866-75 (1997) Article DOI: 10.1021/jm970046b BindingDB Entry DOI: 10.7270/Q2QN67G4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea \|...) Show SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assay				J Med Chem 40: 2866-75 (1997) Article DOI: 10.1021/jm970046b BindingDB Entry DOI: 10.7270/Q2QN67G4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50029559 (2-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assay				J Med Chem 40: 2866-75 (1997) Article DOI: 10.1021/jm970046b BindingDB Entry DOI: 10.7270/Q2QN67G4
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%