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PubMed code 9435911

Compile data set for download or QSAR
Found 36 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50061971
PNG
(CHEMBL138958 | Methyl-[2-(naphthalen-1-yloxy)-ethy...)
Show SMILES CNCCOc1cccc2ccccc12
Show InChI InChI=1S/C13H15NO/c1-14-9-10-15-13-8-4-6-11-5-2-3-7-12(11)13/h2-8,14H,9-10H2,1H3
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 26n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))		BDBM50061971
PNG
(CHEMBL138958 | Methyl-[2-(naphthalen-1-yloxy)-ethy...)
Show SMILES CNCCOc1cccc2ccccc12
Show InChI InChI=1S/C13H15NO/c1-14-9-10-15-13-8-4-6-11-5-2-3-7-12(11)13/h2-8,14H,9-10H2,1H3
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 34n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Compound was tested for its agonist activity against human 5-hydroxytryptamine 1D receptor alpha for comparison purpose.

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50061963
PNG
(CHEMBL136236 | Ethyl-[2-(naphthalen-1-yloxy)-ethyl...)
Show SMILES CCNCCOc1cccc2ccccc12
Show InChI InChI=1S/C14H17NO/c1-2-15-10-11-16-14-9-5-7-12-6-3-4-8-13(12)14/h3-9,15H,2,10-11H2,1H3
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 66n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))		BDBM50061964
PNG
(2-[2-(Naphthalen-1-yloxy)-ethylamino]-ethanol | CH...)
Show SMILES OCCNCCOc1cccc2ccccc12
Show InChI InChI=1S/C14H17NO2/c16-10-8-15-9-11-17-14-7-3-5-12-4-1-2-6-13(12)14/h1-7,15-16H,8-11H2
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 68n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Compound was tested for its agonist activity against human recombinant 5-hydroxytryptamine 1D receptor alpha for comparion purpose.

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))		BDBM50061968
PNG
(CHEMBL140415 | [2-(2-Cyclopentyl-phenoxy)-ethyl]-m...)
Show SMILES CCCN(C)CCOc1ccccc1C1CCCC1
Show InChI InChI=1S/C17H27NO/c1-3-12-18(2)13-14-19-17-11-7-6-10-16(17)15-8-4-5-9-15/h6-7,10-11,15H,3-5,8-9,12-14H2,1-2H3
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 82n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Compound was tested for its agonist activity against human recombinant 5-hydroxytryptamine 1D receptor alpha for comparison purpose.

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50016918
PNG
(CHEMBL139103 | Dimethyl-[2-(naphthalen-1-yloxy)-et...)
Show SMILES CN(C)CCOc1cccc2ccccc12
Show InChI InChI=1S/C14H17NO/c1-15(2)10-11-16-14-9-5-7-12-6-3-4-8-13(12)14/h3-9H,10-11H2,1-2H3
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 94n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50016927
PNG
(2-(Naphthalen-1-yloxy)-ethylamine | CHEMBL337539)
Show SMILES NCCOc1cccc2ccccc12
Show InChI InChI=1S/C12H13NO/c13-8-9-14-12-7-3-5-10-4-1-2-6-11(10)12/h1-7H,8-9,13H2
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 100n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))		BDBM50016909
PNG
(CHEMBL140417 | Methyl-[2-(naphthalen-1-yloxy)-ethy...)
Show SMILES CCCN(C)CCOc1cccc2ccccc12
Show InChI InChI=1S/C16H21NO/c1-3-11-17(2)12-13-18-16-10-6-8-14-7-4-5-9-15(14)16/h4-10H,3,11-13H2,1-2H3
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 103n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Compound was tested for its agonist activity against human recombinant 5-hydroxytryptamine 1D receptor alpha for comparison purpose.

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50061964
PNG
(2-[2-(Naphthalen-1-yloxy)-ethylamino]-ethanol | CH...)
Show SMILES OCCNCCOc1cccc2ccccc12
Show InChI InChI=1S/C14H17NO2/c16-10-8-15-9-11-17-14-7-3-5-12-4-1-2-6-13(12)14/h1-7,15-16H,8-11H2
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 107n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))		BDBM50016913
PNG
(Butyl-ethyl-[2-(naphthalen-1-yloxy)-ethyl]-amine |...)
Show SMILES CCCCN(CC)CCOc1cccc2ccccc12
Show InChI InChI=1S/C18H25NO/c1-3-5-13-19(4-2)14-15-20-18-12-8-10-16-9-6-7-11-17(16)18/h6-12H,3-5,13-15H2,1-2H3
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 112n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Compound was tested for its agonist activity against human recombinant 5-hydroxytryptamine 1D receptor alpha for comparison purpose.

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50061967
PNG
(CHEMBL138963 | Isopropyl-[2-(naphthalen-1-yloxy)-e...)
Show SMILES CC(C)NCCOc1cccc2ccccc12
Show InChI InChI=1S/C15H19NO/c1-12(2)16-10-11-17-15-9-5-7-13-6-3-4-8-14(13)15/h3-9,12,16H,10-11H2,1-2H3
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 120n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))		BDBM50061970
PNG
(CHEMBL136962 | [3-(2-Cyclopentyl-phenoxy)-propyl]-...)
Show SMILES CCCN(C)CCCOc1ccccc1C1CCCC1
Show InChI InChI=1S/C18H29NO/c1-3-13-19(2)14-8-15-20-18-12-7-6-11-17(18)16-9-4-5-10-16/h6-7,11-12,16H,3-5,8-10,13-15H2,1-2H3
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 143n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Compound was tested for its agonist activity against human recombinant 5-hydroxytryptamine 1D receptor alpha for comparison purpose.

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50061974
PNG
(CHEMBL138683 | [2-(Naphthalen-1-yloxy)-ethyl]-prop...)
Show SMILES CCCNCCOc1cccc2ccccc12
Show InChI InChI=1S/C15H19NO/c1-2-10-16-11-12-17-15-9-5-7-13-6-3-4-8-14(13)15/h3-9,16H,2,10-12H2,1H3
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 200n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50016912
PNG
(CHEMBL138136 | Dimethyl-[3-(naphthalen-1-yloxy)-pr...)
Show SMILES CN(C)CCCOc1cccc2ccccc12
Show InChI InChI=1S/C15H19NO/c1-16(2)11-6-12-17-15-10-5-8-13-7-3-4-9-14(13)15/h3-5,7-10H,6,11-12H2,1-2H3
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 255n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50016911
PNG
(Benzyl-methyl-[2-(naphthalen-1-yloxy)-ethyl]-amine...)
Show SMILES CN(CCOc1cccc2ccccc12)Cc1ccccc1
Show InChI InChI=1S/C20H21NO/c1-21(16-17-8-3-2-4-9-17)14-15-22-20-13-7-11-18-10-5-6-12-19(18)20/h2-13H,14-16H2,1H3
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 260n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50061972
PNG
(3-(Naphthalen-1-yloxy)-propylamine | CHEMBL342704)
Show SMILES NCCCOc1cccc2ccccc12
Show InChI InChI=1S/C13H15NO/c14-9-4-10-15-13-8-3-6-11-5-1-2-7-12(11)13/h1-3,5-8H,4,9-10,14H2
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 290n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50454758
PNG
(CHEMBL2112766)
Show SMILES CNCCOc1cccc(C)c1C
Show InChI InChI=1S/C11H17NO/c1-9-5-4-6-11(10(9)2)13-8-7-12-3/h4-6,12H,7-8H2,1-3H3
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 316n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50061968
PNG
(CHEMBL140415 | [2-(2-Cyclopentyl-phenoxy)-ethyl]-m...)
Show SMILES CCCN(C)CCOc1ccccc1C1CCCC1
Show InChI InChI=1S/C17H27NO/c1-3-12-18(2)13-14-19-17-11-7-6-10-16(17)15-8-4-5-9-15/h6-7,10-11,15H,3-5,8-9,12-14H2,1-2H3
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 425n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50016922
PNG
(CHEMBL136470 | Dimethyl-[4-(naphthalen-1-yloxy)-bu...)
Show SMILES CN(C)CCCCOc1cccc2ccccc12
Show InChI InChI=1S/C16H21NO/c1-17(2)12-5-6-13-18-16-11-7-9-14-8-3-4-10-15(14)16/h3-4,7-11H,5-6,12-13H2,1-2H3
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 470n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))		BDBM50016911
PNG
(Benzyl-methyl-[2-(naphthalen-1-yloxy)-ethyl]-amine...)
Show SMILES CN(CCOc1cccc2ccccc12)Cc1ccccc1
Show InChI InChI=1S/C20H21NO/c1-21(16-17-8-3-2-4-9-17)14-15-22-20-13-7-11-18-10-5-6-12-19(18)20/h2-13H,14-16H2,1H3
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 590n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Compound was tested for its agonist activity against human recombinant 5-hydroxytryptamine 1D receptor alpha for comparison purpose.

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50016909
PNG
(CHEMBL140417 | Methyl-[2-(naphthalen-1-yloxy)-ethy...)
Show SMILES CCCN(C)CCOc1cccc2ccccc12
Show InChI InChI=1S/C16H21NO/c1-3-11-17(2)12-13-18-16-10-6-8-14-7-4-5-9-15(14)16/h4-10H,3,11-13H2,1-2H3
PDB

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 750n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50061973
PNG
(CHEMBL139230 | [2-(1H-Indol-4-yloxy)-ethyl]-isopro...)
Show SMILES CC(C)NCCOc1cccc2[nH]ccc12
Show InChI InChI=1S/C13H18N2O/c1-10(2)14-8-9-16-13-5-3-4-12-11(13)6-7-15-12/h3-7,10,14-15H,8-9H2,1-2H3
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 1.12E+3n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50061970
PNG
(CHEMBL136962 | [3-(2-Cyclopentyl-phenoxy)-propyl]-...)
Show SMILES CCCN(C)CCCOc1ccccc1C1CCCC1
Show InChI InChI=1S/C18H29NO/c1-3-13-19(2)14-8-15-20-18-12-7-6-11-17(18)16-9-4-5-10-16/h6-7,11-12,16H,3-5,8-10,13-15H2,1-2H3
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 1.21E+3n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50016913
PNG
(Butyl-ethyl-[2-(naphthalen-1-yloxy)-ethyl]-amine |...)
Show SMILES CCCCN(CC)CCOc1cccc2ccccc12
Show InChI InChI=1S/C18H25NO/c1-3-5-13-19(4-2)14-15-20-18-12-8-10-16-9-6-7-11-17(16)18/h6-12H,3-5,13-15H2,1-2H3
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 1.23E+3n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))		BDBM50061969
PNG
(CHEMBL136311 | Methyl-(2-phenoxy-ethyl)-amine)
Show SMILES CNCCOc1ccccc1
Show InChI InChI=1S/C9H13NO/c1-10-7-8-11-9-5-3-2-4-6-9/h2-6,10H,7-8H2,1H3
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 1.80E+3n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Compound was tested for its agonist activity against human recombinant 5-hydroxytryptamine 1D receptor alpha for comparison purpose.

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50019443
PNG
(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Show SMILES CC(C)NCC(O)COc1cccc2[nH]ccc12
Show InChI InChI=1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3
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 2.60E+3n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50019443
PNG
(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Show SMILES CC(C)NCC(O)COc1cccc2[nH]ccc12
Show InChI InChI=1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3
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 2.60E+3n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50016915
PNG
(CHEMBL334465 | Dibutyl-[2-(naphthalen-1-yloxy)-eth...)
Show SMILES CCCCN(CCCC)CCOc1cccc2ccccc12
Show InChI InChI=1S/C20H29NO/c1-3-5-14-21(15-6-4-2)16-17-22-20-13-9-11-18-10-7-8-12-19(18)20/h7-13H,3-6,14-17H2,1-2H3
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 2.68E+3n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50016910
PNG
(CHEMBL138509 | Methyl-(3-phenoxy-propyl)-amine)
Show SMILES CNCCCOc1ccccc1
Show InChI InChI=1S/C10H15NO/c1-11-8-5-9-12-10-6-3-2-4-7-10/h2-4,6-7,11H,5,8-9H2,1H3
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 3.45E+3n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50246936
PNG
((-)-(S)-Propranolol | 1-(ISOPROPYLAMINO)-3-(1-NAPH...)
Show SMILES CC(C)NC[C@H](O)COc1cccc2ccccc12 |r|
Show InChI InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3/t14-/m0/s1
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 4.10E+3n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50061969
PNG
(CHEMBL136311 | Methyl-(2-phenoxy-ethyl)-amine)
Show SMILES CNCCOc1ccccc1
Show InChI InChI=1S/C9H13NO/c1-10-7-8-11-9-5-3-2-4-6-9/h2-6,10H,7-8H2,1H3
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 5.96E+3n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50061966
PNG
(CHEMBL139737 | Isopropyl-[3-(naphthalen-1-yloxy)-p...)
Show SMILES CC(C)NCCCOc1cccc2ccccc12
Show InChI InChI=1S/C16H21NO/c1-13(2)17-11-6-12-18-16-10-5-8-14-7-3-4-9-15(14)16/h3-5,7-10,13,17H,6,11-12H2,1-2H3
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 7.66E+3n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50016908
PNG
(CHEMBL136072 | Dimethyl-(3-phenoxy-propyl)-amine)
Show SMILES CN(C)CCCOc1ccccc1
Show InChI InChI=1S/C11H17NO/c1-12(2)9-6-10-13-11-7-4-3-5-8-11/h3-5,7-8H,6,9-10H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50016921
PNG
(CHEMBL139976 | N,N-Dimethyl-N'-phenyl-propane-1,3-...)
Show SMILES CN(C)CCCNc1ccccc1
Show InChI InChI=1S/C11H18N2/c1-13(2)10-6-9-12-11-7-4-3-5-8-11/h3-5,7-8,12H,6,9-10H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM25761
PNG
(Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...)
Show SMILES CC(C)NCC(O)COc1cccc2ccccc12
Show InChI InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50061962
PNG
(CHEMBL140358 | [3-(1H-Indol-4-yloxy)-propyl]-isopr...)
Show SMILES CC(C)NCCCOc1cccc2[nH]ccc12
Show InChI InChI=1S/C14H20N2O/c1-11(2)15-8-4-10-17-14-6-3-5-13-12(14)7-9-16-13/h3,5-7,9,11,15-16H,4,8,10H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptor

J Med Chem 40: 4415-9 (1998)


Article DOI: 10.1021/jm970507t
BindingDB Entry DOI: 10.7270/Q2Z038TH
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%