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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272573 (US10065963, 32c | US10376513, Example 346 | US1064...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 32 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272571 (US10065963, Compound 32a | US10376513, Example 345...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 32 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272574 (US10065963, Compound 32d | US10376513, Example 348...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 32 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272572 (US10065963, Compound 32b | US10376513, Example 347...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 32 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM246864 (3-(1- [1,3]oxazolo[5,4- b]pyridin-2- ylpyrrolidin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.8 | 25 |
Incyte Corporation US Patent | Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM262166 (5-{3-(cyanomethyl)- 3-[4-(1H-pyrrolo[2,3- b]pyridi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.8 | 25 |
Incyte Corporation US Patent | Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM246882 (US10053465, 21 | US10065963, Compound 21 | US10125...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.8 | 25 |
Incyte Corporation US Patent | Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272616 (US10065963, Example 31B) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272618 (2-amino-N-(1-(8-chloro-5-(3- cyano-3-methylpyrroli...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272624 (2-Amino-N-(1-[8-chloro-5-(3- methyl-1,1-dioxidothi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272628 (US10065963, Example 41) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272636 (US10065963, Example 49) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272647 (US10065963, Example 60) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272653 (2-Amino-N-{1-[8-chloro-5-(4-fluoropiperidin-1- yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272654 (2-Amino-N-{1-[8-chloro-5-(3,3-difluoropiperidin-1-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272654 (2-Amino-N-{1-[8-chloro-5-(3,3-difluoropiperidin-1-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272657 (2-Amino-N-{1-[8-chloro-5-(2,2-dimethylpyrrolidin-1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272662 (2-Amino-N-{1-[8-chloro-5-(3-fluoropiperidin-1- yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272671 (2-Amino-N-{1-[8-chloro-5-(3-cyano-3-methylpiperidi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272672 (2-Amino-N-(1-{8-chloro-5-[3-hydroxy-3- (trifluorom...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272680 (US10065963, Example 85) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272681 (US10065963, Example 86) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272682 (2-Amino-N-(1-(8-chloro-5-(4-hydroxy-4-methylpiperi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272687 (2-Amino-N-{1-[4-chloro-7-(3-methoxypyrrolidin-1- y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272691 (US10065963, Example 95) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272715 (2-Amino-N-{1-[3,4-dichloro-7-(2,2-dimethyl-1,1- di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272719 (2-Amino-N-[1-(8-chloro-3-methyl-5-pyridin-3- ylimi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272722 (US10065963, Example 123) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272738 (US10065963, Example 139) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272749 (2-Amino-N-(1-{8-chloro-5-[(3S,5S)-3,5- dihydroxypi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272752 (2-Amino-N-{1-[8-chloro-5-(4-cyanopiperidin-1- yl)i...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272755 (2-Amino-N-(1-{8-chloro-5-[(3R,5S)-3,5- dihydroxypi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272757 (2-Amino-N-(1-{8-chloro-5-[(3S,5R)-3-cyano-5- hydro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272777 (US10065963, Example 177) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272779 (2-Amino-N-{1-[8- chloro-5-(1,1- dioxidothio- morph...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272781 (US10065963, Example 181) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM246866 (4-[(4-{3-cyano-2-[4- (7H-pyrrolo[2,3- d]pyrimidin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.8 | 25 |
Incyte Corporation US Patent | Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM246873 (US10053465, 12 | US10065963, Compound 12 | US10125...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.8 | 25 |
Incyte Corporation US Patent | Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM246885 (US10053465, 24 | US10065963, Compound 25 | US10125...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.8 | 25 |
Incyte Corporation US Patent | Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM246888 (US10053465, 26 | US10065963, Compound 26 | US10125...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.8 | 25 |
Incyte Corporation US Patent | Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272579 (2-amino-N-[1-(4-chloro-7-ethoxy-1H-indazol-6-yl)et...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272582 (2-amino-N-{1-[4-chloro- 7-ethoxy-1-(2- methoxyethy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272610 (US10065963, Example 26) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272615 (US10065963, Example 31A) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272616 (US10065963, Example 31B) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272619 (2-Amino-N-(1-(8-chloro-5- ((3S,4S)-3,4-dihydroxypy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272627 (2-Amino-N-(1-[8-chloro-5-(2,2- dimethyl-1,1-dioxid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272629 (US10065963, Example 42) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM272630 (US10065963, Example 43) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM272643 (US10065963, Example 56) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation US Patent | Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... | US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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