Affinity Data by USPatent=US9168247

USPatent US9168247

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50333423 (7-(Pyridin-3-ylmethoxy)-1-methyl-beta-carboline \| ...) Show SMILES Cc1nccc2c3ccc(OCc4cccnc4)cc3[nH]c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
FACULTES UNIVERSITAIRES NOTRE DAME DE LA PAIX; UNIVERSITE LIBRE BRUXELLES US Patent					Assay Description A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of DYRK1A protein kinase. All kinase assay...				US Patent US9168247 (2015) BindingDB Entry DOI: 10.7270/Q2X63KQN
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50395379 (CHEMBL2164712 \| US9168247, CV12) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
FACULTES UNIVERSITAIRES NOTRE DAME DE LA PAIX; UNIVERSITE LIBRE BRUXELLES US Patent					Assay Description A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of DYRK1A protein kinase. All kinase assay...				US Patent US9168247 (2015) BindingDB Entry DOI: 10.7270/Q2X63KQN
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50333416 (7-(2-Methoxyethoxy)-1-methyl-beta-carboline \| CHEM...) Show SMILES COCCOc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	7.5	n/a
FACULTES UNIVERSITAIRES NOTRE DAME DE LA PAIX; UNIVERSITE LIBRE BRUXELLES US Patent					Assay Description A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of DYRK1A protein kinase. All kinase assay...				US Patent US9168247 (2015) BindingDB Entry DOI: 10.7270/Q2X63KQN
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50395380 (CHEMBL2164709 \| US9168247, JR84) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	7.5	n/a
FACULTES UNIVERSITAIRES NOTRE DAME DE LA PAIX; UNIVERSITE LIBRE BRUXELLES US Patent					Assay Description A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of DYRK1A protein kinase. All kinase assay...				US Patent US9168247 (2015) BindingDB Entry DOI: 10.7270/Q2X63KQN
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50395381 (CHEMBL2164716 \| US9168247, JR95) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	7.5	n/a
FACULTES UNIVERSITAIRES NOTRE DAME DE LA PAIX; UNIVERSITE LIBRE BRUXELLES US Patent					Assay Description A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of DYRK1A protein kinase. All kinase assay...				US Patent US9168247 (2015) BindingDB Entry DOI: 10.7270/Q2X63KQN
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50395378 (CHEMBL2164696 \| US9168247, CV24) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	7.5	n/a
FACULTES UNIVERSITAIRES NOTRE DAME DE LA PAIX; UNIVERSITE LIBRE BRUXELLES US Patent					Assay Description A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of DYRK1A protein kinase. All kinase assay...				US Patent US9168247 (2015) BindingDB Entry DOI: 10.7270/Q2X63KQN
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%