Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Eyes absent homolog 3 (Homo sapiens (Human)) | BDBM50209206 ((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodopheny...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 (Homo sapiens (Human)) | BDBM50158465 ((4-hydroxy-3,5-diiodophenyl)(2-methylbenzofuran-3-...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 (Homo sapiens (Human)) | BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 [223-510] (Homo sapiens (Human)) | BDBM18964 (4-[(2-butyl-1-benzofuran-3-yl)carbonyl]phenol | L ...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 [223-510] (Homo sapiens (Human)) | BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 (Homo sapiens (Human)) | BDBM330348 (US9725430, Compound 1e | US9962362, Compound 1e) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 (Homo sapiens (Human)) | BDBM18964 (4-[(2-butyl-1-benzofuran-3-yl)carbonyl]phenol | L ...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 (Homo sapiens (Human)) | BDBM50342278 ((2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 (Homo sapiens (Human)) | BDBM330350 (US9725430, Compound 1f | US9962362, Compound 1f) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 1.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 [223-510] (Homo sapiens (Human)) | BDBM50342278 ((2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.92E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 (Homo sapiens (Human)) | BDBM50342279 ((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxy-be...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 2.72E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 (Homo sapiens (Human)) | BDBM50342287 ((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxyben...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 (Homo sapiens (Human)) | BDBM330353 (US9725430, Compound 1i | US9962362, Compound 1i) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 5.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM18964 (4-[(2-butyl-1-benzofuran-3-yl)carbonyl]phenol | L ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 7.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 (Homo sapiens (Human)) | BDBM50342276 ((2-Ethyl-5-hydroxybenzofuran-3-yl)(4-hydroxyphenyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 (Homo sapiens (Human)) | BDBM50158457 ((4-hydroxyphenyl)(2-methylbenzofuran-3-yl)methanon...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 8.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50342278 ((2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | >1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair |