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USPatent US9932325

Compile Data Set for Download or QSAR

Found 215 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384294
PNG
(US10590114, No. 5 | US11111235, No. 5 | US11591316...)
Show SMILES Cc1nn(cc1Nc1ncc(c(NC2C3CC2C3)n1)C(F)(F)F)C(C)(C)C#N |(-4.47,-1.87,;-2.93,-1.87,;-2.02,-3.12,;-.56,-2.64,;-.56,-1.1,;-2.02,-.63,;-2.42,.86,;-1.33,1.95,;-1.73,3.44,;-.64,4.53,;.85,4.13,;1.25,2.64,;2.73,2.24,;3.13,.76,;2.36,-.58,;3.7,-1.35,;4.47,-.01,;3.58,-.9,;.16,1.55,;1.94,5.22,;3.42,4.82,;1.54,6.71,;3.03,6.31,;.53,-3.73,;2.02,-4.13,;1.62,-2.64,;.13,-5.22,;-.26,-6.71,)|
Show InChI InChI=1S/C18H20F3N7/c1-9-13(7-28(27-9)17(2,3)8-22)24-16-23-6-12(18(19,20)21)15(26-16)25-14-10-4-11(14)5-10/h6-7,10-11,14H,4-5H2,1-3H3,(H2,23,24,25,26)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384307
PNG
(US11591316, Compound 11 | US9932325, Example 11)
Show SMILES CNc1nc(Nc2cnn(C3CC4[C@H](C3)C4(F)F)c2C)ncc1C(F)(F)F |r|
Show InChI InChI=1S/C16H17F5N6/c1-7-12(6-24-27(7)8-3-9-10(4-8)15(9,17)18)25-14-23-5-11(16(19,20)21)13(22-2)26-14/h5-6,8-10H,3-4H2,1-2H3,(H2,22,23,25,26)/t8?,9-,10?/m0/s1
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384323
PNG
(US10590114, No. 24 | US11111235, No. 24 | US115913...)
Show SMILES CCNc1nc(Nc2cn(nc2C)C2(C)CCN(C)C2=O)ncc1C(F)(F)F
Show InChI InChI=1S/C17H22F3N7O/c1-5-21-13-11(17(18,19)20)8-22-15(24-13)23-12-9-27(25-10(12)2)16(3)6-7-26(4)14(16)28/h8-9H,5-7H2,1-4H3,(H2,21,22,23,24)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384352
PNG
(US10590114, No. 37 | US11111235, No. 37 | US115913...)
Show SMILES COc1nc(Nc2cnn(C3CCC3)c2C#N)ncc1Br
Show InChI InChI=1S/C13H13BrN6O/c1-21-12-9(14)6-16-13(19-12)18-10-7-17-20(11(10)5-15)8-3-2-4-8/h6-8H,2-4H2,1H3,(H,16,18,19)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384358
PNG
(US10590114, No. 41 | US11111235, No. 41 | US115913...)
Show SMILES COc1nc(Nc2cn(nc2C)C(C)(C)C#N)ncc1Br
Show InChI InChI=1S/C13H15BrN6O/c1-8-10(6-20(19-8)13(2,3)7-15)17-12-16-5-9(14)11(18-12)21-4/h5-6H,1-4H3,(H,16,17,18)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384361
PNG
(BDBM384388 | BDBM384401 | US10590114, No. 89 | US1...)
Show SMILES CCNc1nc(Nc2cn(nc2C)C(C)(C)C#N)ncc1C(F)(F)F
Show InChI InChI=1S/C15H18F3N7/c1-5-20-12-10(15(16,17)18)6-21-13(23-12)22-11-7-25(24-9(11)2)14(3,4)8-19/h6-7H,5H2,1-4H3,(H2,20,21,22,23)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384363
PNG
(BDBM384372 | US10590114, No. 59 | US11111235, No. ...)
Show SMILES Cc1nn(cc1Nc1ncc(c(NCC(F)F)n1)C(F)(F)F)C(C)(C)C#N
Show InChI InChI=1S/C15H16F5N7/c1-8-10(6-27(26-8)14(2,3)7-21)24-13-23-4-9(15(18,19)20)12(25-13)22-5-11(16)17/h4,6,11H,5H2,1-3H3,(H2,22,23,24,25)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384365
PNG
(US10590114, No. 50 | US11111235, No. 50 | US115913...)
Show SMILES CCNc1nc(Nc2cnn3CC(F)Cc23)ncc1C(F)(F)F
Show InChI InChI=1S/C13H14F4N6/c1-2-18-11-8(13(15,16)17)4-19-12(22-11)21-9-5-20-23-6-7(14)3-10(9)23/h4-5,7H,2-3,6H2,1H3,(H2,18,19,21,22)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384363
PNG
(BDBM384372 | US10590114, No. 59 | US11111235, No. ...)
Show SMILES Cc1nn(cc1Nc1ncc(c(NCC(F)F)n1)C(F)(F)F)C(C)(C)C#N
Show InChI InChI=1S/C15H16F5N7/c1-8-10(6-27(26-8)14(2,3)7-21)24-13-23-4-9(15(18,19)20)12(25-13)22-5-11(16)17/h4,6,11H,5H2,1-3H3,(H2,22,23,24,25)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM50448118
PNG
(CHEMBL3122113 | US10590114, No. 80 | US11111235, N...)
Show SMILES CNc1nc(Nc2cn(nc2C)C(C)(C)C#N)ncc1C(F)(F)F
Show InChI InChI=1S/C14H16F3N7/c1-8-10(6-24(23-8)13(2,3)7-18)21-12-20-5-9(14(15,16)17)11(19-4)22-12/h5-6H,1-4H3,(H2,19,20,21,22)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384382
PNG
(US10590114, No. 71 | US11111235, No. 69 | US115913...)
Show SMILES Cn1nc(cc1Nc1ncc(c(NC2CC2)n1)C(F)(F)F)C(C)(C)n1nccn1
Show InChI InChI=1S/C17H20F3N9/c1-16(2,29-22-6-7-23-29)12-8-13(28(3)27-12)25-15-21-9-11(17(18,19)20)14(26-15)24-10-4-5-10/h6-10H,4-5H2,1-3H3,(H2,21,24,25,26)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384390
PNG
(US10590114, No. 76 | US11111235, No. 76 | US115913...)
Show SMILES Cc1nn(cc1Nc1ncc(c(NC(CF)CF)n1)C(F)(F)F)C(C)(C)C#N
Show InChI InChI=1S/C16H18F5N7/c1-9-12(7-28(27-9)15(2,3)8-22)25-14-23-6-11(16(19,20)21)13(26-14)24-10(4-17)5-18/h6-7,10H,4-5H2,1-3H3,(H2,23,24,25,26)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384402
PNG
(US10590114, No. 129 | US11111235, No. 88 | US11591...)
Show SMILES CCNc1nc(Nc2cc(nn2CC)C(C)(C)n2nccn2)ncc1C(F)(F)F
Show InChI InChI=1S/C17H22F3N9/c1-5-21-14-11(17(18,19)20)10-22-15(26-14)25-13-9-12(27-28(13)6-2)16(3,4)29-23-7-8-24-29/h7-10H,5-6H2,1-4H3,(H2,21,22,25,26)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384407
PNG
(US10590114, No. 93 | US11111235, No. 93 | US115913...)
Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C(C)(C)C#N)ncc1Br
Show InChI InChI=1S/C16H20BrN7/c1-4-19-14-11(17)7-20-15(22-14)21-12-8-24(16(2,3)9-18)23-13(12)10-5-6-10/h7-8,10H,4-6H2,1-3H3,(H2,19,20,21,22)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384419
PNG
(US10590114, No. 105 | US11111235, No. 105 | US1159...)
Show SMILES CCNc1nc(Nc2cnn(c2C2CC2)-c2cnccn2)ncc1C(F)(F)F
Show InChI InChI=1S/C17H17F3N8/c1-2-22-15-11(17(18,19)20)7-24-16(27-15)26-12-8-25-28(14(12)10-3-4-10)13-9-21-5-6-23-13/h5-10H,2-4H2,1H3,(H2,22,24,26,27)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384426
PNG
(US10590114, No. 112 | US11111235, No. 112 | US1159...)
Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)S(C)(=O)=O)ncc1C(F)(F)F
Show InChI InChI=1S/C14H17F3N6O2S/c1-3-18-12-9(14(15,16)17)6-19-13(21-12)20-10-7-23(26(2,24)25)22-11(10)8-4-5-8/h6-8H,3-5H2,1-2H3,(H2,18,19,20,21)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384440
PNG
(US10590114, No. 126 | US11111235, No. 126 | US1159...)
Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)(C)n2nccn2)ncc1Br
Show InChI InChI=1S/C17H22BrN9/c1-4-19-15-12(18)10-20-16(24-15)23-14-9-13(25-26(14)11-5-6-11)17(2,3)27-21-7-8-22-27/h7-11H,4-6H2,1-3H3,(H2,19,20,23,24)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384457
PNG
(US10590114, No. 144 | US11111235, Compound 143 | U...)
Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F
Show InChI InChI=1S/C18H21F3N6O2/c1-3-22-14-11(18(19,20)21)9-23-16(25-14)24-13-8-12(26-27(13)10-4-5-10)17(2)6-7-29-15(17)28/h8-10H,3-7H2,1-2H3,(H2,22,23,24,25)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384482
PNG
(US10590114, No. 168 | US11591316, Compound 168 | U...)
Show SMILES CNc1nc(Nc2cc(nn2C2CC2)[C@]23C[C@H]2COC3=O)ncc1C(F)(F)F |r|
Show InChI InChI=1S/C17H17F3N6O2/c1-21-13-10(17(18,19)20)6-22-15(24-13)23-12-4-11(25-26(12)9-2-3-9)16-5-8(16)7-28-14(16)27/h4,6,8-9H,2-3,5,7H2,1H3,(H2,21,22,23,24)/t8-,16-/m0/s1
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384483
PNG
(US10590114, No. 169 | US11111235, No. 169 | US1159...)
Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)[C@H]2C[C@H]2C(=O)OCC)ncc1C(F)(F)F |r|
Show InChI InChI=1S/C19H23F3N6O2/c1-3-23-16-13(19(20,21)22)9-24-18(26-16)25-15-8-14(27-28(15)10-5-6-10)11-7-12(11)17(29)30-4-2/h8-12H,3-7H2,1-2H3,(H2,23,24,25,26)/t11-,12+/m0/s1
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384487
PNG
(US10590114, No. 174 | US11111235, No. 174 | US1159...)
Show SMILES CCNc1nc(Nc2cc(nn2C)C2(C)CCOC2=O)ncc1C(F)(F)F
Show InChI InChI=1S/C16H19F3N6O2/c1-4-20-12-9(16(17,18)19)8-21-14(23-12)22-11-7-10(24-25(11)3)15(2)5-6-27-13(15)26/h7-8H,4-6H2,1-3H3,(H2,20,21,22,23)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384523
PNG
(US10590114, No. 209 | US11111235, No. 209 | US1159...)
Show SMILES CNc1nc(Nc2cn(nc2C2CC2)C2C[C@H]2C#N)ncc1C(F)(F)F |r|
Show InChI InChI=1S/C16H16F3N7/c1-21-14-10(16(17,18)19)6-22-15(24-14)23-11-7-26(12-4-9(12)5-20)25-13(11)8-2-3-8/h6-9,12H,2-4H2,1H3,(H2,21,22,23,24)/t9-,12?/m0/s1
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384524
PNG
(US10590114, No. 211 | US11111235, No. 211 | US1159...)
Show SMILES FC(F)CNc1nc(Nc2cn(nc2C2CC2)C2C[C@H]2C#N)ncc1C(F)(F)F |r|
Show InChI InChI=1S/C17H16F5N7/c18-13(19)6-24-15-10(17(20,21)22)5-25-16(27-15)26-11-7-29(12-3-9(12)4-23)28-14(11)8-1-2-8/h5,7-9,12-13H,1-3,6H2,(H2,24,25,26,27)/t9-,12?/m0/s1
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384311
PNG
(US10590114, No. 15 | US11111235, No. 15 | US115913...)
Show SMILES CNc1nc(Nc2cn(nc2C)C(C)(C)c2ccn(C)n2)ncc1C(F)(F)F
Show InChI InChI=1S/C17H21F3N8/c1-10-12(9-28(25-10)16(2,3)13-6-7-27(5)26-13)23-15-22-8-11(17(18,19)20)14(21-4)24-15/h6-9H,1-5H3,(H2,21,22,23,24)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384328
PNG
(US10590114, No. 25 | US11111235, No. 25 | US115913...)
Show SMILES CCNc1nc(Nc2cn(nc2C)C2CCN(C)C2=O)ncc1C(F)(F)F
Show InChI InChI=1S/C16H20F3N7O/c1-4-20-13-10(16(17,18)19)7-21-15(23-13)22-11-8-26(24-9(11)2)12-5-6-25(3)14(12)27/h7-8,12H,4-6H2,1-3H3,(H2,20,21,22,23)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384350
PNG
(US10590114, No. 35B | US11111235, No. 35B | US1159...)
Show SMILES CCNc1nc(Nc2cn(nc2C)[C@@H]2C[C@@H](C2)C#N)ncc1C(F)(F)F |r,wD:13.13,15.18,(4.7,.38,;3.37,1.15,;3.37,2.69,;2.03,3.46,;.7,2.69,;-.63,3.46,;-1.97,2.69,;-1.97,1.15,;-.72,.25,;-1.2,-1.22,;-2.74,-1.22,;-3.21,.25,;-4.7,.65,;-.43,-2.55,;1.06,-2.95,;.67,-4.46,;-.83,-4.04,;1.44,-5.79,;2.21,-7.13,;-.63,5,;.7,5.77,;2.08,5.03,;3.42,5.8,;4.75,6.57,;2.65,7.13,;4.19,4.47,)|
Show InChI InChI=1S/C16H18F3N7/c1-3-21-14-12(16(17,18)19)7-22-15(24-14)23-13-8-26(25-9(13)2)11-4-10(5-11)6-20/h7-8,10-11H,3-5H2,1-2H3,(H2,21,22,23,24)/t10-,11+
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM50448118
PNG
(CHEMBL3122113 | US10590114, No. 80 | US11111235, N...)
Show SMILES CNc1nc(Nc2cn(nc2C)C(C)(C)C#N)ncc1C(F)(F)F
Show InChI InChI=1S/C14H16F3N7/c1-8-10(6-24(23-8)13(2,3)7-18)21-12-20-5-9(14(15,16)17)11(19-4)22-12/h5-6H,1-4H3,(H2,19,20,21,22)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384366
PNG
(US10590114, No. 52B | US11111235, No. 52B | US1159...)
Show SMILES CCNc1nc(Nc2cnn3CC(Cc23)C#N)ncc1C(F)(F)F
Show InChI InChI=1S/C14H14F3N7/c1-2-19-12-9(14(15,16)17)5-20-13(23-12)22-10-6-21-24-7-8(4-18)3-11(10)24/h5-6,8H,2-3,7H2,1H3,(H2,19,20,22,23)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384371
PNG
(US11111235, No. 58 | US11591316, Compound 58 | US9...)
Show SMILES CCNc1nc(Nc2cnn(C3CCC3)c2C#N)ncc1Br
Show InChI InChI=1S/C14H16BrN7/c1-2-17-13-10(15)7-18-14(21-13)20-11-8-19-22(12(11)6-16)9-4-3-5-9/h7-9H,2-5H2,1H3,(H2,17,18,20,21)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384373
PNG
(US10590114, No. 60 | US11111235, No. 60 | US115913...)
Show SMILES Cc1nn(cc1Nc1ncc(Cl)c(OC2CC2)n1)C(C)(C)C#N
Show InChI InChI=1S/C15H17ClN6O/c1-9-12(7-22(21-9)15(2,3)8-17)19-14-18-6-11(16)13(20-14)23-10-4-5-10/h6-7,10H,4-5H2,1-3H3,(H,18,19,20)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM50448118
PNG
(CHEMBL3122113 | US10590114, No. 80 | US11111235, N...)
Show SMILES CNc1nc(Nc2cn(nc2C)C(C)(C)C#N)ncc1C(F)(F)F
Show InChI InChI=1S/C14H16F3N7/c1-8-10(6-24(23-8)13(2,3)7-18)21-12-20-5-9(14(15,16)17)11(19-4)22-12/h5-6H,1-4H3,(H2,19,20,21,22)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384386
PNG
(US10590114, No. 72 | US11111235, No. 72 | US115913...)
Show SMILES Cc1nn(cc1Nc1ncc(Cl)c(NC2CC2)n1)C(C)(C)C#N
Show InChI InChI=1S/C15H18ClN7/c1-9-12(7-23(22-9)15(2,3)8-17)20-14-18-6-11(16)13(21-14)19-10-4-5-10/h6-7,10H,4-5H2,1-3H3,(H2,18,19,20,21)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384361
PNG
(BDBM384388 | BDBM384401 | US10590114, No. 89 | US1...)
Show SMILES CCNc1nc(Nc2cn(nc2C)C(C)(C)C#N)ncc1C(F)(F)F
Show InChI InChI=1S/C15H18F3N7/c1-5-20-12-10(15(16,17)18)6-21-13(23-12)22-11-7-25(24-9(11)2)14(3,4)8-19/h6-7H,5H2,1-4H3,(H2,20,21,22,23)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384396
PNG
(US10590114, No. 82 | US11111235, No. 82 | US115913...)
Show SMILES CCNc1nc(Nc2cc(nn2C)C(C)(C)c2ncco2)ncc1C(F)(F)F
Show InChI InChI=1S/C17H20F3N7O/c1-5-21-13-10(17(18,19)20)9-23-15(25-13)24-12-8-11(26-27(12)4)16(2,3)14-22-6-7-28-14/h6-9H,5H2,1-4H3,(H2,21,23,24,25)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384397
PNG
(US10590114, No. 83 | US11111235, No. 83 | US115913...)
Show SMILES CCNc1nc(Nc2cc(n(C)n2)C(C)(C)c2ncco2)ncc1C(F)(F)F
Show InChI InChI=1S/C17H20F3N7O/c1-5-21-13-10(17(18,19)20)9-23-15(25-13)24-12-8-11(27(4)26-12)16(2,3)14-22-6-7-28-14/h6-9H,5H2,1-4H3,(H2,21,23,24,25,26)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384400
PNG
(US11111235, No. 86 | US11591316, Compound 86 | US9...)
Show SMILES CCNc1nc(Nc2cc(nn2C(C)C)C(C)(C)n2nccn2)ncc1C(F)(F)F
Show InChI InChI=1S/C18H24F3N9/c1-6-22-15-12(18(19,20)21)10-23-16(27-15)26-14-9-13(28-29(14)11(2)3)17(4,5)30-24-7-8-25-30/h7-11H,6H2,1-5H3,(H2,22,23,26,27)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384405
PNG
(US10590114, No. 108 | US11111235, No. 91 | US11591...)
Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F
Show InChI InChI=1S/C18H21F3N6O2/c1-3-22-14-11(18(19,20)21)8-23-16(25-14)24-12-9-27(26-13(12)10-4-5-10)17(2)6-7-29-15(17)28/h8-10H,3-7H2,1-2H3,(H2,22,23,24,25)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384423
PNG
(US10590114, No. 109 | US11111235, No. 109 | US1159...)
Show SMILES CNc1nc(Nc2c[nH]nc2C)ncc1C(F)(F)F
Show InChI InChI=1S/C10H11F3N6/c1-5-7(4-16-19-5)17-9-15-3-6(10(11,12)13)8(14-2)18-9/h3-4H,1-2H3,(H,16,19)(H2,14,15,17,18)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384413
PNG
(US10590114, No. 123 | US11111235, No. 99 | US11591...)
Show SMILES CNc1nc(Nc2cn(nc2Cl)C2(C)CCOC2=O)ncc1C(F)(F)F
Show InChI InChI=1S/C14H14ClF3N6O2/c1-13(3-4-26-11(13)25)24-6-8(9(15)23-24)21-12-20-5-7(14(16,17)18)10(19-2)22-12/h5-6H,3-4H2,1-2H3,(H2,19,20,21,22)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384433
PNG
(US10590114, No. 124 | US11111235, No. 124 | US1159...)
Show SMILES CNc1nc(Nc2cn(nc2C)C2(C)CCOC2=O)ncc1C(F)(F)F
Show InChI InChI=1S/C15H17F3N6O2/c1-8-10(7-24(23-8)14(2)4-5-26-12(14)25)21-13-20-6-9(15(16,17)18)11(19-3)22-13/h6-7H,4-5H2,1-3H3,(H2,19,20,21,22)
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Universita degli Studi di Firenze



Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384451
PNG
(US10590114, No. 138 | US11111235, No. 138 | US1159...)
Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)n2nccn2)ncc1C(F)(F)F
Show InChI InChI=1S/C17H20F3N9/c1-3-21-15-12(17(18,19)20)9-22-16(26-15)25-14-8-13(27-28(14)11-4-5-11)10(2)29-23-6-7-24-29/h6-11H,3-5H2,1-2H3,(H2,21,22,25,26)
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Universita degli Studi di Firenze



Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384457
PNG
(US10590114, No. 144 | US11111235, Compound 143 | U...)
Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F
Show InChI InChI=1S/C18H21F3N6O2/c1-3-22-14-11(18(19,20)21)9-23-16(25-14)24-13-8-12(26-27(13)10-4-5-10)17(2)6-7-29-15(17)28/h8-10H,3-7H2,1-2H3,(H2,22,23,24,25)
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Universita degli Studi di Firenze



Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384469
PNG
(US10590114, No. 156 | US11111235, Compound 155 | U...)
Show SMILES CNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F
Show InChI InChI=1S/C17H19F3N6O2/c1-16(5-6-28-14(16)27)11-7-12(26(25-11)9-3-4-9)23-15-22-8-10(17(18,19)20)13(21-2)24-15/h7-9H,3-6H2,1-2H3,(H2,21,22,23,24)
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Universita degli Studi di Firenze



Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384472
PNG
(US10590114, No. 158 | US11111235, No. 158 | US1159...)
Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)N2CCCC2=O)ncc1Br
Show InChI InChI=1S/C16H20BrN7O/c1-2-18-15-11(17)9-19-16(21-15)20-12-8-13(22-24(12)10-5-6-10)23-7-3-4-14(23)25/h8-10H,2-7H2,1H3,(H2,18,19,20,21)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384496
PNG
(US10590114, No. 182 | US11111235, No. 182 | US1159...)
Show SMILES CCNc1nc(Nc2ccnn2[C@H]2C[C@@H](C2)n2nccn2)ncc1C(F)(F)F |r,wU:12.12,wD:14.17,(7.74,-2.67,;6.41,-1.9,;6.41,-.36,;5.08,.41,;3.74,-.36,;2.41,.41,;1.07,-.36,;1.07,-1.9,;2.32,-2.8,;1.84,-4.26,;.3,-4.26,;-.17,-2.8,;-1.66,-2.4,;-2.99,-3.17,;-3.76,-1.84,;-2.43,-1.07,;-5.25,-1.44,;-5.73,.03,;-7.27,.03,;-7.74,-1.44,;-6.5,-2.34,;2.41,1.95,;3.74,2.72,;5.08,1.95,;6.41,2.72,;6.41,4.26,;7.74,1.95,;7.74,3.49,)|
Show InChI InChI=1S/C16H18F3N9/c1-2-20-14-12(16(17,18)19)9-21-15(26-14)25-13-3-4-22-27(13)10-7-11(8-10)28-23-5-6-24-28/h3-6,9-11H,2,7-8H2,1H3,(H2,20,21,25,26)/t10-,11-
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384500
PNG
(US10590114, No. 187 | US11111235, No. 187 | US1159...)
Show SMILES CCNc1nc(Nc2cc(nn2C)C2(C)CCCO2)ncc1C(F)(F)F
Show InChI InChI=1S/C16H21F3N6O/c1-4-20-13-10(16(17,18)19)9-21-14(23-13)22-12-8-11(24-25(12)3)15(2)6-5-7-26-15/h8-9H,4-7H2,1-3H3,(H2,20,21,22,23)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384516
PNG
(US10590114, No. 203 | US11111235, No. 203 | US1159...)
Show SMILES CCN1CCC(F)(F)C(C1)n1ncc(Nc2ncc(c(NC)n2)C(F)(F)F)c1Cl
Show InChI InChI=1S/C16H19ClF5N7/c1-3-28-5-4-15(18,19)11(8-28)29-12(17)10(7-25-29)26-14-24-6-9(16(20,21)22)13(23-2)27-14/h6-7,11H,3-5,8H2,1-2H3,(H2,23,24,26,27)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384526
PNG
(US10590114, No. 212 | US11111235, No. 212 | US1159...)
Show SMILES COc1nc(Nc2cn(nc2C2CC2)C2C[C@@H]2C#N)ncc1Br |r|
Show InChI InChI=1S/C15H15BrN6O/c1-23-14-10(16)6-18-15(20-14)19-11-7-22(12-4-9(12)5-17)21-13(11)8-2-3-8/h6-9,12H,2-4H2,1H3,(H,18,19,20)/t9-,12?/m1/s1
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384528
PNG
(US10590114, No. 214 | US11111235, No. 214 | US1159...)
Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C2C[C@@H]2C#N)ncc1Br |r|
Show InChI InChI=1S/C16H18BrN7/c1-2-19-15-11(17)7-20-16(22-15)21-12-8-24(13-5-10(13)6-18)23-14(12)9-3-4-9/h7-10,13H,2-5H2,1H3,(H2,19,20,21,22)/t10-,13?/m1/s1
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]


(Homo sapiens (Human))		BDBM384530
PNG
(US10590114, No. 217 | US11111235, No. 217 | US1159...)
Show SMILES CCNc1nc(Nc2cn(nc2C)C2(CF)CCOC2=O)ncc1C(F)(F)F
Show InChI InChI=1S/C16H18F4N6O2/c1-3-21-12-10(16(18,19)20)6-22-14(24-12)23-11-7-26(25-9(11)2)15(8-17)4-5-28-13(15)27/h6-7H,3-5,8H2,1-2H3,(H2,21,22,23,24)
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Assay Description
Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...

Bioorg Med Chem Lett 18: 2567-73 (2008)


BindingDB Entry DOI: 10.7270/Q29G5Q4M
More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%