| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 9 [133-239] |
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| Ligand | BDBM621681 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | BRD9 Bromodomain TR-FRET Competition Binding Assay |
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| IC50 | <10±n/a nM |
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| Citation |  Zhou, Q; Bocker, M; Millan, DS; Chan, HM; Soares, L; Netherton, MR; Ruppel, SK; Yang, Z; Lowe, JT; Brucelle, F Methods and compounds for treating disorders US Patent US11773085 Publication Date 10/3/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Bromodomain-containing protein 9 [133-239] |
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| Name: | Bromodomain-containing protein 9 [133-239] |
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| Synonyms: | BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 (BRD9)(133-239) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12383.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | aa 133-239 |
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| Residue: | 107 |
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| Sequence: | PAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVA
NEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK
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| BDBM621681 |
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| n/a |
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| Name | BDBM621681 |
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| Synonyms: | 4-[4-[(dimethylamino)methyl]-3-methoxy-5-(methylsulfanyl)phenyl]-2-methyl-1,2-dihydro-2,7-naphthyridin-1-one | US11773085, Compound B54 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23N3O2S |
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| Mol. Mass. | 369.481 |
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| SMILES | COc1cc(cc(SC)c1CN(C)C)-c1cn(C)c(=O)c2cnccc12 |
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| Structure | 
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