Reaction Details |
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Target | Trace amine-associated receptor 1 |
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Ligand | BDBM330212 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Radioligand Binding Assay on Rat |
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IC50 | 39.3±n/a nM |
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Citation | Cecere, G; Galley, G; Hu, Y; Norcross, R; Pflieger, P; Shen, H 5-oxa-2-azabicyclo[2.2.2]OCTAN-4-yl and 5-oxa-2-azabicyclo[2.2.1]heptan-4-yl derivatives US Patent US9663530 Publication Date 5/30/2017 |
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More Info.: | Get all data from this article, Assay Method |
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Trace amine-associated receptor 1 |
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Name: | Trace amine-associated receptor 1 |
Synonyms: | TAAR1_MOUSE | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1 |
Type: | Protein |
Mol. Mass.: | 37635.41 |
Organism: | Mus musculus (Mouse) |
Description: | Q923Y8 |
Residue: | 332 |
Sequence: | MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWL
LHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDR
YCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGG
CSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQ
SKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMV
YAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
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BDBM330212 |
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n/a |
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Name | BDBM330212 |
Synonyms: | N-[4-[(1R,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-yl]phenyl]-2-(trifluoromethyl)pyrimidin-4-amine | US9663530, Example 56 |
Type | Small organic molecule |
Emp. Form. | C16H15F3N4O |
Mol. Mass. | 336.3117 |
SMILES | FC(F)(F)c1nccc(Nc2ccc(cc2)[C@@]23CN[C@@H](CO2)C3)n1 |r| |
Structure |
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