Compile Data Set for Download or QSAR

Found 3464 hits with Last Name = 'galley' and Initial = 'g'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122323 (US8729113, 35) Show SMILES NC1=N[C@@H](CCOc2cccc(Br)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H13BrN2O2/c12-8-2-1-3-10(6-8)15-5-4-9-7-16-11(13)14-9/h1-3,6,9H,4-5,7H2,(H2,13,14)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	-53.1	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109401 (US8604061, 115) Show SMILES Cc1cccc(CC[C@H]2COC(N)=N2)c1 |r,c:12| Show InChI InChI=1S/C12H16N2O/c1-9-3-2-4-10(7-9)5-6-11-8-15-12(13)14-11/h2-4,7,11H,5-6,8H2,1H3,(H2,13,14)/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240677 (US9416127, 14 | US9416127, 15) Show SMILES FC(F)(F)Oc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O3/c21-20(22,23)31-16-7-5-15(6-8-16)28-25-11-17(27-28)19(29)26-14-3-1-13(2-4-14)18-12-24-9-10-30-18/h1-8,11,18,24H,9-10,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50027473 (3-Methyl-1-phenethyl-4-(phenyl-propionyl-amino)-pi...) Show SMILES CCC(=O)N(c1ccccc1)[C@]1(CCN(CCc2ccccc2)C[C@H]1C)C(=O)OC Show InChI InChI=1S/C25H32N2O3/c1-4-23(28)27(22-13-9-6-10-14-22)25(24(29)30-3)16-18-26(19-20(25)2)17-15-21-11-7-5-8-12-21/h5-14,20H,4,15-19H2,1-3H3/t20-,25+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Competitive binding displacement analyses was performed from permanently transfected HEK293 cells expressing Opioid receptor mu 1				J Med Chem 43: 1329-38 (2001) BindingDB Entry DOI: 10.7270/Q2ZG6SZG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM256431 (US9487501, 32) Show SMILES Cc1nn(cc1C(=O)Nc1ccc(cc1)[C@H]1CNCCO1)-c1ccc(OC(F)F)cc1 |r| Show InChI InChI=1S/C22H22F2N4O3/c1-14-19(13-28(27-14)17-6-8-18(9-7-17)31-22(23)24)21(29)26-16-4-2-15(3-5-16)20-12-25-10-11-30-20/h2-9,13,20,22,25H,10-12H2,1H3,(H,26,29)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	-57.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				US Patent US9487501 (2016) BindingDB Entry DOI: 10.7270/Q2BZ650Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240666 (US9416127, 16 | US9416127, 3) Show SMILES FC(F)Oc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H19F2N5O3/c21-20(22)30-16-7-5-15(6-8-16)27-24-11-17(26-27)19(28)25-14-3-1-13(2-4-14)18-12-23-9-10-29-18/h1-8,11,18,20,23H,9-10,12H2,(H,25,28)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122301 (US8729113, 8) Show SMILES NC1=N[C@@H](CCOc2ccc(F)c(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H12ClFN2O2/c12-9-5-8(1-2-10(9)13)16-4-3-7-6-17-11(14)15-7/h1-2,5,7H,3-4,6H2,(H2,14,15)/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	-51.5	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240675 (US9416127, 12) Show SMILES Clc1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18ClN5O2/c20-14-2-1-3-16(10-14)25-22-11-17(24-25)19(26)23-15-6-4-13(5-7-15)18-12-21-8-9-27-18/h1-7,10-11,18,21H,8-9,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240673 (US9416127, 10) Show SMILES FC(F)(F)c1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O2/c21-20(22,23)14-3-7-16(8-4-14)28-25-11-17(27-28)19(29)26-15-5-1-13(2-6-15)18-12-24-9-10-30-18/h1-8,11,18,24H,9-10,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240670 (US9416127, 7) Show SMILES Cc1nn(nc1C(=O)Nc1ccc(cc1)[C@@H]1CNCCO1)-c1ccccc1 |r| Show InChI InChI=1S/C20H21N5O2/c1-14-19(24-25(23-14)17-5-3-2-4-6-17)20(26)22-16-9-7-15(8-10-16)18-13-21-11-12-27-18/h2-10,18,21H,11-13H2,1H3,(H,22,26)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109373 (US8604061, 48) Show SMILES NC1=N[C@@H](Cc2cccc3ccccc23)CO1 |r,t:1| Show InChI InChI=1S/C14H14N2O/c15-14-16-12(9-17-14)8-11-6-3-5-10-4-1-2-7-13(10)11/h1-7,12H,8-9H2,(H2,15,16)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240675 (US9416127, 12) Show SMILES Clc1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18ClN5O2/c20-14-2-1-3-16(10-14)25-22-11-17(24-25)19(26)23-15-6-4-13(5-7-15)18-12-21-8-9-27-18/h1-7,10-11,18,21H,8-9,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	-57.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109462 (US8604061, 201) Show SMILES NC1=N[C@H](CO1)c1cc(Cl)cc(Cl)c1 |r,t:1| Show InChI InChI=1S/C9H8Cl2N2O/c10-6-1-5(2-7(11)3-6)8-4-14-9(12)13-8/h1-3,8H,4H2,(H2,12,13)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240669 (US9416127, 6) Show SMILES Clc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18ClN5O2/c20-14-3-7-16(8-4-14)25-22-11-17(24-25)19(26)23-15-5-1-13(2-6-15)18-12-21-9-10-27-18/h1-8,11,18,21H,9-10,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240677 (US9416127, 14 | US9416127, 15) Show SMILES FC(F)(F)Oc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O3/c21-20(22,23)31-16-7-5-15(6-8-16)28-25-11-17(27-28)19(29)26-14-3-1-13(2-4-14)18-12-24-9-10-30-18/h1-8,11,18,24H,9-10,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	-57.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240666 (US9416127, 16 | US9416127, 3) Show SMILES FC(F)Oc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H19F2N5O3/c21-20(22)30-16-7-5-15(6-8-16)27-24-11-17(26-27)19(28)25-14-3-1-13(2-4-14)18-12-23-9-10-29-18/h1-8,11,18,20,23H,9-10,12H2,(H,25,28)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240676 (US9416127, 13) Show SMILES FC(F)(F)c1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O2/c21-20(22,23)14-2-1-3-16(10-14)28-25-11-17(27-28)19(29)26-15-6-4-13(5-7-15)18-12-24-8-9-30-18/h1-7,10-11,18,24H,8-9,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240668 (US9416127, 11 | US9416127, 5) Show SMILES Fc1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18FN5O2/c20-14-2-1-3-16(10-14)25-22-11-17(24-25)19(26)23-15-6-4-13(5-7-15)18-12-21-8-9-27-18/h1-7,10-11,18,21H,8-9,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190607 (US9181230, 13) Show SMILES Fc1ccc(-c2cc(n[nH]2)-c2ccc(cc2)[C@H]2CNCCO2)c(F)c1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM167453 (US9073911, 2) Show SMILES Clc1cccc(c1)-c1cc(n[nH]1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122333 (US8729113, 57) Show SMILES NC1=N[C@@H](CCOc2ccc(Cl)c(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H12Cl2N2O2/c12-9-2-1-8(5-10(9)13)16-4-3-7-6-17-11(14)15-7/h1-2,5,7H,3-4,6H2,(H2,14,15)/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-50.5	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122298 (US8729113, 5) Show SMILES NC1=N[C@@H](CCOc2cccc(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H13ClN2O2/c12-8-2-1-3-10(6-8)15-5-4-9-7-16-11(13)14-9/h1-3,6,9H,4-5,7H2,(H2,13,14)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-50.5	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109564 (US8604061, 354) Show SMILES NC1=N[C@@H](COc2ccccc2F)CO1 |r,t:1| Show InChI InChI=1S/C10H11FN2O2/c11-8-3-1-2-4-9(8)14-5-7-6-15-10(12)13-7/h1-4,7H,5-6H2,(H2,12,13)/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM109581 (US8604061, 316) Show SMILES NC1=N[C@H](CO1)c1ccc(Br)cc1Cl |r,t:1| Show InChI InChI=1S/C9H8BrClN2O/c10-5-1-2-6(7(11)3-5)8-4-14-9(12)13-8/h1-3,8H,4H2,(H2,12,13)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109408 (US8604061, 127) Show SMILES NC1=N[C@@H](CCc2ccc(Cl)c(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H12Cl2N2O/c12-9-4-2-7(5-10(9)13)1-3-8-6-16-11(14)15-8/h2,4-5,8H,1,3,6H2,(H2,14,15)/t8-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190621 (US9181230, 27) Show SMILES Fc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C18H17FN4O/c19-15-5-1-13(2-6-15)17-12-23(22-21-17)16-7-3-14(4-8-16)18-11-20-9-10-24-18/h1-8,12,18,20H,9-11H2/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240677 (US9416127, 14 | US9416127, 15) Show SMILES FC(F)(F)Oc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O3/c21-20(22,23)31-16-7-5-15(6-8-16)28-25-11-17(27-28)19(29)26-14-3-1-13(2-4-14)18-12-24-9-10-30-18/h1-8,11,18,24H,9-10,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190602 (US9181230, 8) Show SMILES Clc1ccc(cc1)-c1cc(n[nH]1)-c1ccc(cc1)[C@@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM167466 (US9073911, 15) Show SMILES Clc1cccc(c1)-c1cc([nH]n1)C(=O)Nc1ccc(cc1)[C@@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109390 (US8604061, 103) Show SMILES NC1=N[C@H](CO1)c1ccc2ccccc2c1 |r,t:1| Show InChI InChI=1S/C13H12N2O/c14-13-15-12(8-16-13)11-6-5-9-3-1-2-4-10(9)7-11/h1-7,12H,8H2,(H2,14,15)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM167463 (US9073911, 12) Show SMILES Clc1ccc(cc1)-c1cc([nH]n1)C(=O)Nc1ccc(cc1)[C@@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50178575 (2-(3,5-bis(trifluoromethyl)phenyl)-N-(6-(4-hydroxy...) Show SMILES CN(C(=O)C(C)(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cnc(cc1-c1ccccc1C)N1CCC(O)CC1 Show InChI InChI=1S/C30H31F6N3O2/c1-18-7-5-6-8-23(18)24-16-26(39-11-9-22(40)10-12-39)37-17-25(24)38(4)27(41)28(2,3)19-13-20(29(31,32)33)15-21(14-19)30(34,35)36/h5-8,13-17,22,40H,9-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-labeled substance P from cloned human NK1 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 1362-5 (2006) Article DOI: 10.1016/j.bmcl.2005.11.047 BindingDB Entry DOI: 10.7270/Q2D50MJP
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109446 (US8604061, 178) Show SMILES NC1=N[C@H](CO1)c1cc(F)cc(Cl)c1 |r,t:1| Show InChI InChI=1S/C9H8ClFN2O/c10-6-1-5(2-7(11)3-6)8-4-14-9(12)13-8/h1-3,8H,4H2,(H2,12,13)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM167453 (US9073911, 2) Show SMILES Clc1cccc(c1)-c1cc(n[nH]1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109580 (US8604061, 296) Show SMILES NC1=N[C@H](CO1)c1ccc(Cl)cc1Cl |r,t:1| Show InChI InChI=1S/C9H8Cl2N2O/c10-5-1-2-6(7(11)3-5)8-4-14-9(12)13-8/h1-3,8H,4H2,(H2,12,13)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109528 (US8604061, 298) Show SMILES NC1=N[C@H](CO1)c1cc(Cl)ccc1Cl |r,t:1| Show InChI InChI=1S/C9H8Cl2N2O/c10-5-1-2-7(11)6(3-5)8-4-14-9(12)13-8/h1-3,8H,4H2,(H2,12,13)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122318 (US8729113, 30) Show SMILES NC1=N[C@@H](CCC2(CC2)c2ccc(Cl)cc2)CO1 |r,t:1| Show InChI InChI=1S/C14H17ClN2O/c15-11-3-1-10(2-4-11)14(7-8-14)6-5-12-9-18-13(16)17-12/h1-4,12H,5-9H2,(H2,16,17)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-49.9	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM60837 (US9181230, 9) Show SMILES Clc1cccc(c1)-c1cc(n[nH]1)-c1ccc(cc1)C1CNCCO1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122380 (US8729113, 136) Show SMILES NC1=N[C@@H](CCOc2cccc(c2)C(=O)OCc2ccccc2)CO1 |r,t:1| Show InChI InChI=1S/C19H20N2O4/c20-19-21-16(13-25-19)9-10-23-17-8-4-7-15(11-17)18(22)24-12-14-5-2-1-3-6-14/h1-8,11,16H,9-10,12-13H2,(H2,20,21)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-49.9	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240669 (US9416127, 6) Show SMILES Clc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18ClN5O2/c20-14-3-7-16(8-4-14)25-22-11-17(24-25)19(26)23-15-5-1-13(2-6-15)18-12-21-9-10-27-18/h1-8,11,18,21H,9-10,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240668 (US9416127, 11 | US9416127, 5) Show SMILES Fc1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18FN5O2/c20-14-2-1-3-16(10-14)25-22-11-17(24-25)19(26)23-15-6-4-13(5-7-15)18-12-21-8-9-27-18/h1-7,10-11,18,21H,8-9,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240667 (US9416127, 4 | US9416127, 9) Show SMILES Fc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18FN5O2/c20-14-3-7-16(8-4-14)25-22-11-17(24-25)19(26)23-15-5-1-13(2-6-15)18-12-21-9-10-27-18/h1-8,11,18,21H,9-10,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240673 (US9416127, 10) Show SMILES FC(F)(F)c1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O2/c21-20(22,23)14-3-7-16(8-4-14)28-25-11-17(27-28)19(29)26-15-5-1-13(2-6-15)18-12-24-9-10-30-18/h1-8,11,18,24H,9-10,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50178558 (2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-...) Show SMILES CN(C(=O)C(C)(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cnc(nc1-c1ccccc1C)N1CCN(C)CC1 Show InChI InChI=1S/C29H31F6N5O/c1-18-8-6-7-9-22(18)24-23(17-36-26(37-24)40-12-10-38(4)11-13-40)39(5)25(41)27(2,3)19-14-20(28(30,31)32)16-21(15-19)29(33,34)35/h6-9,14-17H,10-13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-labeled substance P from cloned human NK1 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 1362-5 (2006) Article DOI: 10.1016/j.bmcl.2005.11.047 BindingDB Entry DOI: 10.7270/Q2D50MJP
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM390718 ((S)-1-(6-Amino-5,6,7,8-tetrahydronaphthalen-2-yl)-...) Show SMILES N[C@H]1CCc2cc(NC(=O)Nc3ccc(Cl)cc3)ccc2C1 |r| Show InChI InChI=1S/C17H18ClN3O/c18-13-3-7-15(8-4-13)20-17(22)21-16-6-2-11-9-14(19)5-1-12(11)10-16/h2-4,6-8,10,14H,1,5,9,19H2,(H2,20,21,22)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description Mouse:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%,...				Bioorg Med Chem Lett 19: 1168-72 (2009) BindingDB Entry DOI: 10.7270/Q2V1275M
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM158299 (US9029370, 93) Show SMILES FC(F)Oc1ccc(cc1)-n1cc(cn1)C(=O)Nc1ccc([C@@H]2CNCCO2)c(Cl)c1 |r| Show InChI InChI=1S/C21H19ClF2N4O3/c22-18-9-14(1-6-17(18)19-11-25-7-8-30-19)27-20(29)13-10-26-28(12-13)15-2-4-16(5-3-15)31-21(23)24/h1-6,9-10,12,19,21,25H,7-8,11H2,(H,27,29)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	-55.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description Membrane Preparation and Radioligand Binding. HEK-293 cells stably expressing mouse TAA 1 were maintained at 37 C and 5% C02 in DMEM high glucose med...				US Patent US9029370 (2015) BindingDB Entry DOI: 10.7270/Q2NP235N
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM167461 (US9073911, 10) Show SMILES Clc1ccccc1-c1cc([nH]n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM167463 (US9073911, 12) Show SMILES Clc1ccc(cc1)-c1cc([nH]n1)C(=O)Nc1ccc(cc1)[C@@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM167491 (US9073911, 40) Show SMILES FC(F)Oc1cccc(c1)-c1cc([nH]n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM60838 (US9181230, 12) Show SMILES N#Cc1cccc(c1)-c1cc(n[nH]1)-c1ccc(cc1)C1CNCCO1 Show InChI InChI=1S/C20H18N4O/c21-12-14-2-1-3-17(10-14)19-11-18(23-24-19)15-4-6-16(7-5-15)20-13-22-8-9-25-20/h1-7,10-11,20,22H,8-9,13H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	-55.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair

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