| Reaction Details |
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 | Report a problem with these data |
| Target | Trace amine-associated receptor 1 |
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| Ligand | BDBM390718 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding |
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| Ki | 0.500±n/a nM |
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| Citation |  Cecere, G; Galley, G; Goergler, A; Norcross, R; Pflieger, P; Tirla, A; Schmid, P 6-amino-5,6,7,8-tetrahydronaphthalen-2-yl or 3-aminochroman-7-yl derivatives US Patent US9957261 Publication Date 5/1/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Trace amine-associated receptor 1 |
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| Name: | Trace amine-associated receptor 1 |
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| Synonyms: | TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 38034.73 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q923Y9 |
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| Residue: | 332 |
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| Sequence: | MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWL
LHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDR
YYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRG
CFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQ
SKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMV
YAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
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| BDBM390718 |
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| n/a |
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| Name | BDBM390718 |
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| Synonyms: | (S)-1-(6-Amino-5,6,7,8-tetrahydronaphthalen-2-yl)-3-(4-chlorophenyl)urea | US9957261, Example 74 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18ClN3O |
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| Mol. Mass. | 315.797 |
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| SMILES | N[C@H]1CCc2cc(NC(=O)Nc3ccc(Cl)cc3)ccc2C1 |r| |
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| Structure | 
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