Compile Data Set for Download or QSAR

Found 1035 hits with Last Name = 'goergler' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122323 (US8729113, 35) Show SMILES NC1=N[C@@H](CCOc2cccc(Br)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H13BrN2O2/c12-8-2-1-3-10(6-8)15-5-4-9-7-16-11(13)14-9/h1-3,6,9H,4-5,7H2,(H2,13,14)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	-53.1	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122301 (US8729113, 8) Show SMILES NC1=N[C@@H](CCOc2ccc(F)c(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H12ClFN2O2/c12-9-5-8(1-2-10(9)13)16-4-3-7-6-17-11(14)15-7/h1-2,5,7H,3-4,6H2,(H2,14,15)/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	-51.5	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122333 (US8729113, 57) Show SMILES NC1=N[C@@H](CCOc2ccc(Cl)c(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H12Cl2N2O2/c12-9-2-1-8(5-10(9)13)16-4-3-7-6-17-11(14)15-7/h1-2,5,7H,3-4,6H2,(H2,14,15)/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-50.5	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122298 (US8729113, 5) Show SMILES NC1=N[C@@H](CCOc2cccc(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H13ClN2O2/c12-8-2-1-3-10(6-8)15-5-4-9-7-16-11(13)14-9/h1-3,6,9H,4-5,7H2,(H2,13,14)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-50.5	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190607 (US9181230, 13) Show SMILES Fc1ccc(-c2cc(n[nH]2)-c2ccc(cc2)[C@H]2CNCCO2)c(F)c1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190602 (US9181230, 8) Show SMILES Clc1ccc(cc1)-c1cc(n[nH]1)-c1ccc(cc1)[C@@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122318 (US8729113, 30) Show SMILES NC1=N[C@@H](CCC2(CC2)c2ccc(Cl)cc2)CO1 |r,t:1| Show InChI InChI=1S/C14H17ClN2O/c15-11-3-1-10(2-4-11)14(7-8-14)6-5-12-9-18-13(16)17-12/h1-4,12H,5-9H2,(H2,16,17)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-49.9	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190621 (US9181230, 27) Show SMILES Fc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C18H17FN4O/c19-15-5-1-13(2-6-15)17-12-23(22-21-17)16-7-3-14(4-8-16)18-11-20-9-10-24-18/h1-8,12,18,20H,9-11H2/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM60837 (US9181230, 9) Show SMILES Clc1cccc(c1)-c1cc(n[nH]1)-c1ccc(cc1)C1CNCCO1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122380 (US8729113, 136) Show SMILES NC1=N[C@@H](CCOc2cccc(c2)C(=O)OCc2ccccc2)CO1 |r,t:1| Show InChI InChI=1S/C19H20N2O4/c20-19-21-16(13-25-19)9-10-23-17-8-4-7-15(11-17)18(22)24-12-14-5-2-1-3-6-14/h1-8,11,16H,9-10,12-13H2,(H2,20,21)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-49.9	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM60838 (US9181230, 12) Show SMILES N#Cc1cccc(c1)-c1cc(n[nH]1)-c1ccc(cc1)C1CNCCO1 Show InChI InChI=1S/C20H18N4O/c21-12-14-2-1-3-17(10-14)19-11-18(23-24-19)15-4-6-16(7-5-15)20-13-22-8-9-25-20/h1-7,10-11,20,22H,8-9,13H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	-55.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122296 (US8729113, 3) Show SMILES NC1=N[C@@H](CCOc2ccc(Cl)cc2)CO1 |r,t:1| Show InChI InChI=1S/C11H13ClN2O2/c12-8-1-3-10(4-2-8)15-6-5-9-7-16-11(13)14-9/h1-4,9H,5-7H2,(H2,13,14)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	-49.3	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122319 (US8729113, 31) Show SMILES NC1=N[C@@H](CCC2(CC2)c2ccccc2)CO1 |r,t:1| Show InChI InChI=1S/C14H18N2O/c15-13-16-12(10-17-13)6-7-14(8-9-14)11-4-2-1-3-5-11/h1-5,12H,6-10H2,(H2,15,16)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	-49.3	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM390718 ((S)-1-(6-Amino-5,6,7,8-tetrahydronaphthalen-2-yl)-...) Show SMILES N[C@H]1CCc2cc(NC(=O)Nc3ccc(Cl)cc3)ccc2C1 |r| Show InChI InChI=1S/C17H18ClN3O/c18-13-3-7-15(8-4-13)20-17(22)21-16-6-2-11-9-14(19)5-1-12(11)10-16/h2-4,6-8,10,14H,1,5,9,19H2,(H2,20,21,22)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description Mouse:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%,...				Bioorg Med Chem Lett 19: 1168-72 (2009) BindingDB Entry DOI: 10.7270/Q2V1275M
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122385 (US8729113, 144) Show SMILES NC1=N[C@@H](CCC2(CC2)c2ccc(Br)cc2)CO1 |r,t:1| Show InChI InChI=1S/C14H17BrN2O/c15-11-3-1-10(2-4-11)14(7-8-14)6-5-12-9-18-13(16)17-12/h1-4,12H,5-9H2,(H2,16,17)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	-49.3	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122357 (US8729113, 91) Show SMILES NC1=N[C@@H](CCC2(CC2)c2ccc(F)c(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C14H16ClFN2O/c15-11-7-9(1-2-12(11)16)14(5-6-14)4-3-10-8-19-13(17)18-10/h1-2,7,10H,3-6,8H2,(H2,17,18)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.600	-48.9	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM390701 ((S)-N-(6-Amino-5,6,7,8-tetrahydronaphthalen-2-yl)-...) Show SMILES N[C@H]1CCc2cc(NC(=O)c3ccc4ccccc4c3)ccc2C1 |r| Show InChI InChI=1S/C21H20N2O/c22-19-9-7-17-13-20(10-8-16(17)12-19)23-21(24)18-6-5-14-3-1-2-4-15(14)11-18/h1-6,8,10-11,13,19H,7,9,12,22H2,(H,23,24)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description Rat:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				Bioorg Med Chem Lett 19: 1168-72 (2009) BindingDB Entry DOI: 10.7270/Q2V1275M
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190620 (US9181230, 26) Show SMILES Fc1ccc(cc1)-n1cc(cn1)-c1ccc(cc1)[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18FN3O/c20-17-5-7-18(8-6-17)23-13-16(11-22-23)14-1-3-15(4-2-14)19-12-21-9-10-24-19/h1-8,11,13,19,21H,9-10,12H2/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.600	-54.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122320 (US8729113, 32) Show SMILES Cc1cccc(OCC[C@H]2COC(N)=N2)c1 |r,c:13| Show InChI InChI=1S/C12H16N2O2/c1-9-3-2-4-11(7-9)15-6-5-10-8-16-12(13)14-10/h2-4,7,10H,5-6,8H2,1H3,(H2,13,14)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.700	-48.6	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190623 (US9181230, 29) Show SMILES Fc1ccc(cc1)-c1cc(n[nH]1)-c1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.700	-54.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122386 (US8729113, 150) Show SMILES NC1=N[C@@H](CCSc2ccc(F)cc2)CO1 |r,t:1| Show InChI InChI=1S/C11H13FN2OS/c12-8-1-3-10(4-2-8)16-6-5-9-7-15-11(13)14-9/h1-4,9H,5-7H2,(H2,13,14)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.700	-48.6	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122315 (US8729113, 26) Show SMILES CC(C)(CC[C@H]1COC(N)=N1)c1ccc(Cl)cc1 |r,c:9| Show InChI InChI=1S/C14H19ClN2O/c1-14(2,10-3-5-11(15)6-4-10)8-7-12-9-18-13(16)17-12/h3-6,12H,7-9H2,1-2H3,(H2,16,17)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.700	-48.6	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122377 (US8729113, 130) Show SMILES NC1=N[C@@H](CCOc2cc(F)cc(F)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H12F2N2O2/c12-7-3-8(13)5-10(4-7)16-2-1-9-6-17-11(14)15-9/h3-5,9H,1-2,6H2,(H2,14,15)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.700	-48.6	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122373 (US8729113, 122) Show SMILES CC[C@@H](C[C@H]1COC(N)=N1)Oc1ccc(Cl)c(Cl)c1 |r,c:8| Show InChI InChI=1S/C13H16Cl2N2O2/c1-2-9(5-8-7-18-13(16)17-8)19-10-3-4-11(14)12(15)6-10/h3-4,6,8-9H,2,5,7H2,1H3,(H2,16,17)/t8-,9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.700	-48.6	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190608 (US9181230, 14) Show SMILES Fc1ccc(-c2cc(n[nH]2)-c2ccc(cc2)[C@@H]2CNCCO2)c(F)c1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.800	-54.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM390723 ((S)-6-Amino-N-(3-(trifluoromethoxy)phenyl)-5,6,7,8...) Show SMILES N[C@H]1CCc2cc(ccc2C1)C(=O)Nc1cccc(OC(F)(F)F)c1 |r| Show InChI InChI=1S/C18H17F3N2O2/c19-18(20,21)25-16-3-1-2-15(10-16)23-17(24)13-5-4-12-9-14(22)7-6-11(12)8-13/h1-5,8,10,14H,6-7,9,22H2,(H,23,24)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description Rat:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				Bioorg Med Chem Lett 19: 1168-72 (2009) BindingDB Entry DOI: 10.7270/Q2V1275M
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122322 (US8729113, 34) Show SMILES NC1=N[C@@H](CCOc2cccc(OCc3ccccc3)c2)CO1 |r,t:1| Show InChI InChI=1S/C18H20N2O3/c19-18-20-15(13-23-18)9-10-21-16-7-4-8-17(11-16)22-12-14-5-2-1-3-6-14/h1-8,11,15H,9-10,12-13H2,(H2,19,20)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.800	-48.3	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122384 (US8729113, 143) Show SMILES NC1=N[C@@H](CCC2(CC2)c2cc(F)cc(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C14H16ClFN2O/c15-10-5-9(6-11(16)7-10)14(3-4-14)2-1-12-8-19-13(17)18-12/h5-7,12H,1-4,8H2,(H2,17,18)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.900	-48.0	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122297 (US8729113, 4) Show SMILES NC1=N[C@@H](CCOc2cccc(c2)C(F)(F)F)CO1 |r,t:1| Show InChI InChI=1S/C12H13F3N2O2/c13-12(14,15)8-2-1-3-10(6-8)18-5-4-9-7-19-11(16)17-9/h1-3,6,9H,4-5,7H2,(H2,16,17)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.900	-48.0	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM390731 ((R)-N-(3-Aminochroman-7-yl)-3,4-difluorobenzamide ...) Show SMILES N[C@H]1COc2cc(NC(=O)c3ccc(F)c(F)c3)ccc2C1 |r| Show InChI InChI=1S/C16H14F2N2O2/c17-13-4-2-10(6-14(13)18)16(21)20-12-3-1-9-5-11(19)8-22-15(9)7-12/h1-4,6-7,11H,5,8,19H2,(H,20,21)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description Rat:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				Bioorg Med Chem Lett 19: 1168-72 (2009) BindingDB Entry DOI: 10.7270/Q2V1275M
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM390729 ((R)-N-(3-Aminochroman-7-yl)-1-methyl-5-(thiophen-2...) Show SMILES Cn1nc(cc1-c1cccs1)C(=O)Nc1ccc2C[C@@H](N)COc2c1 |r| Show InChI InChI=1S/C18H18N4O2S/c1-22-15(17-3-2-6-25-17)9-14(21-22)18(23)20-13-5-4-11-7-12(19)10-24-16(11)8-13/h2-6,8-9,12H,7,10,19H2,1H3,(H,20,23)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description Rat:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				Bioorg Med Chem Lett 19: 1168-72 (2009) BindingDB Entry DOI: 10.7270/Q2V1275M
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122381 (US8729113, 140) Show SMILES CC[C@@H](C[C@H]1COC(N)=N1)Oc1cccc(OCc2ccccc2)c1 |r,c:8| Show InChI InChI=1S/C20H24N2O3/c1-2-17(11-16-14-24-20(21)22-16)25-19-10-6-9-18(12-19)23-13-15-7-4-3-5-8-15/h3-10,12,16-17H,2,11,13-14H2,1H3,(H2,21,22)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.900	-48.0	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM390723 ((S)-6-Amino-N-(3-(trifluoromethoxy)phenyl)-5,6,7,8...) Show SMILES N[C@H]1CCc2cc(ccc2C1)C(=O)Nc1cccc(OC(F)(F)F)c1 |r| Show InChI InChI=1S/C18H17F3N2O2/c19-18(20,21)25-16-3-1-2-15(10-16)23-17(24)13-5-4-12-9-14(22)7-6-11(12)8-13/h1-5,8,10,14H,6-7,9,22H2,(H,23,24)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description Mouse:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%,...				Bioorg Med Chem Lett 19: 1168-72 (2009) BindingDB Entry DOI: 10.7270/Q2V1275M
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM106590 (US8586617, 51) Show SMILES Clc1cccc(c1)N(CC1CC1)Cc1cnc[nH]1 Show InChI InChI=1S/C14H16ClN3/c15-12-2-1-3-14(6-12)18(8-11-4-5-11)9-13-7-16-10-17-13/h1-3,6-7,10-11H,4-5,8-9H2,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.900	-48.0	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay: The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazoline was used at a concentration equal to the calcula...				US Patent US8586617 (2013) BindingDB Entry DOI: 10.7270/Q2GF0S56
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM390716 ((S)-1-(6-Amino-5,6,7,8-tetrahydronaphthalen-2-yl)-...) Show SMILES N[C@H]1CCc2cc(NC(=O)Nc3ccc(cc3)C3CC3)ccc2C1 |r| Show InChI InChI=1S/C20H23N3O/c21-17-7-3-16-12-19(10-6-15(16)11-17)23-20(24)22-18-8-4-14(5-9-18)13-1-2-13/h4-6,8-10,12-13,17H,1-3,7,11,21H2,(H2,22,23,24)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description Mouse:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%,...				Bioorg Med Chem Lett 19: 1168-72 (2009) BindingDB Entry DOI: 10.7270/Q2V1275M
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM106671 (US8586617, 331) Show SMILES CC(C)N(Cc1cnc[nH]1)c1ccc(Br)c(Cl)c1 Show InChI InChI=1S/C13H15BrClN3/c1-9(2)18(7-10-6-16-8-17-10)11-3-4-12(14)13(15)5-11/h3-6,8-9H,7H2,1-2H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	-47.8	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay: The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazoline was used at a concentration equal to the calcula...				US Patent US8586617 (2013) BindingDB Entry DOI: 10.7270/Q2GF0S56
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM106665 (US8586617, 308) Show SMILES CCN(Cc1cnc[nH]1)c1cc(F)cc(Cl)c1 Show InChI InChI=1S/C12H13ClFN3/c1-2-17(7-11-6-15-8-16-11)12-4-9(13)3-10(14)5-12/h3-6,8H,2,7H2,1H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	-47.8	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay: The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazoline was used at a concentration equal to the calcula...				US Patent US8586617 (2013) BindingDB Entry DOI: 10.7270/Q2GF0S56
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM390716 ((S)-1-(6-Amino-5,6,7,8-tetrahydronaphthalen-2-yl)-...) Show SMILES N[C@H]1CCc2cc(NC(=O)Nc3ccc(cc3)C3CC3)ccc2C1 |r| Show InChI InChI=1S/C20H23N3O/c21-17-7-3-16-12-19(10-6-15(16)11-17)23-20(24)22-18-8-4-14(5-9-18)13-1-2-13/h4-6,8-10,12-13,17H,1-3,7,11,21H2,(H2,22,23,24)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description Rat:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				Bioorg Med Chem Lett 19: 1168-72 (2009) BindingDB Entry DOI: 10.7270/Q2V1275M
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM390701 ((S)-N-(6-Amino-5,6,7,8-tetrahydronaphthalen-2-yl)-...) Show SMILES N[C@H]1CCc2cc(NC(=O)c3ccc4ccccc4c3)ccc2C1 |r| Show InChI InChI=1S/C21H20N2O/c22-19-9-7-17-13-20(10-8-16(17)12-19)23-21(24)18-6-5-14-3-1-2-4-15(14)11-18/h1-6,8,10-11,13,19H,7,9,12,22H2,(H,23,24)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description Mouse:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%,...				Bioorg Med Chem Lett 19: 1168-72 (2009) BindingDB Entry DOI: 10.7270/Q2V1275M
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122363 (US8729113, 111) Show SMILES CC[C@@H](C[C@H]1COC(N)=N1)Oc1ccc(Br)cc1 |r,c:8| Show InChI InChI=1S/C13H17BrN2O2/c1-2-11(7-10-8-17-13(15)16-10)18-12-5-3-9(14)4-6-12/h3-6,10-11H,2,7-8H2,1H3,(H2,15,16)/t10-,11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	-47.8	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122359 (US8729113, 107) Show SMILES CC[C@@H](C[C@H]1COC(N)=N1)Oc1ccc(Cl)cc1 |r,c:8| Show InChI InChI=1S/C13H17ClN2O2/c1-2-11(7-10-8-17-13(15)16-10)18-12-5-3-9(14)4-6-12/h3-6,10-11H,2,7-8H2,1H3,(H2,15,16)/t10-,11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	-47.8	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122348 (US8729113, 75) Show SMILES C[C@@H](C[C@H]1COC(N)=N1)Oc1ccc(Cl)c(Cl)c1 |r,c:7| Show InChI InChI=1S/C12H14Cl2N2O2/c1-7(4-8-6-17-12(15)16-8)18-9-2-3-10(13)11(14)5-9/h2-3,5,7-8H,4,6H2,1H3,(H2,15,16)/t7-,8-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	-47.8	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122338 (US8729113, 63) Show SMILES NC1=N[C@@H](CCOc2cccc(c2)C#N)CO1 |r,t:1| Show InChI InChI=1S/C12H13N3O2/c13-7-9-2-1-3-11(6-9)16-5-4-10-8-17-12(14)15-10/h1-3,6,10H,4-5,8H2,(H2,14,15)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	-47.8	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM390718 ((S)-1-(6-Amino-5,6,7,8-tetrahydronaphthalen-2-yl)-...) Show SMILES N[C@H]1CCc2cc(NC(=O)Nc3ccc(Cl)cc3)ccc2C1 |r| Show InChI InChI=1S/C17H18ClN3O/c18-13-3-7-15(8-4-13)20-17(22)21-16-6-2-11-9-14(19)5-1-12(11)10-16/h2-4,6-8,10,14H,1,5,9,19H2,(H2,20,21,22)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description Rat:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				Bioorg Med Chem Lett 19: 1168-72 (2009) BindingDB Entry DOI: 10.7270/Q2V1275M
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190633 (US9181230, 39) Show SMILES Fc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C18H17FN4O/c19-15-5-1-13(2-6-15)17-12-23(22-21-17)16-7-3-14(4-8-16)18-11-20-9-10-24-18/h1-8,12,18,20H,9-11H2/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	-53.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190625 (US9181230, 31) Show SMILES Fc1ccc(cc1)-c1cc(n[nH]1)-c1ccc(cc1)[C@@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	-53.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190622 (US9181230, 28) Show SMILES N#Cc1ccc(cc1)-c1cc(n[nH]1)-c1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	-53.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM106631 (US8586617, 192) Show SMILES CCN(Cc1cnc[nH]1)c1cccc(OCc2ccccc2)c1 Show InChI InChI=1S/C19H21N3O/c1-2-22(13-17-12-20-15-21-17)18-9-6-10-19(11-18)23-14-16-7-4-3-5-8-16/h3-12,15H,2,13-14H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	-47.8	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay: The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazoline was used at a concentration equal to the calcula...				US Patent US8586617 (2013) BindingDB Entry DOI: 10.7270/Q2GF0S56
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM47082 (CHEMBL2206377 | US8586617, 24) Show SMILES CC(C)N(Cc1cnc[nH]1)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C13H15Cl2N3/c1-9(2)18(7-12-6-16-8-17-12)13-4-10(14)3-11(15)5-13/h3-6,8-9H,7H2,1-2H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay: The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazoline was used at a concentration equal to the calcula...				US Patent US8586617 (2013) BindingDB Entry DOI: 10.7270/Q2GF0S56
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190597 (US9181230, 3) Show SMILES Clc1ccc(cc1)-c1cc(n[nH]1)-c1ccc(cc1)C1CNCCO1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	-53.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair

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