Compile Data Set for Download or QSAR

Found 3473 hits with Last Name = 'pflieger' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240677 (US9416127, 14 | US9416127, 15) Show SMILES FC(F)(F)Oc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O3/c21-20(22,23)31-16-7-5-15(6-8-16)28-25-11-17(27-28)19(29)26-14-3-1-13(2-4-14)18-12-24-9-10-30-18/h1-8,11,18,24H,9-10,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240673 (US9416127, 10) Show SMILES FC(F)(F)c1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O2/c21-20(22,23)14-3-7-16(8-4-14)28-25-11-17(27-28)19(29)26-15-5-1-13(2-6-15)18-12-24-9-10-30-18/h1-8,11,18,24H,9-10,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240666 (US9416127, 16 | US9416127, 3) Show SMILES FC(F)Oc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H19F2N5O3/c21-20(22)30-16-7-5-15(6-8-16)27-24-11-17(26-27)19(28)25-14-3-1-13(2-4-14)18-12-23-9-10-29-18/h1-8,11,18,20,23H,9-10,12H2,(H,25,28)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240675 (US9416127, 12) Show SMILES Clc1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18ClN5O2/c20-14-2-1-3-16(10-14)25-22-11-17(24-25)19(26)23-15-6-4-13(5-7-15)18-12-21-8-9-27-18/h1-7,10-11,18,21H,8-9,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM256431 (US9487501, 32) Show SMILES Cc1nn(cc1C(=O)Nc1ccc(cc1)[C@H]1CNCCO1)-c1ccc(OC(F)F)cc1 |r| Show InChI InChI=1S/C22H22F2N4O3/c1-14-19(13-28(27-14)17-6-8-18(9-7-17)31-22(23)24)21(29)26-16-4-2-15(3-5-16)20-12-25-10-11-30-20/h2-9,13,20,22,25H,10-12H2,1H3,(H,26,29)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	-57.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				US Patent US9487501 (2016) BindingDB Entry DOI: 10.7270/Q2BZ650Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250244 (US11697636, Example 154 | US9452980, 154) Show SMILES Clc1ccc(cc1Cl)C(=O)Nc1ccc(CCC2CCCN2)cc1 Show InChI InChI=1S/C19H20Cl2N2O/c20-17-10-6-14(12-18(17)21)19(24)23-16-8-4-13(5-9-16)3-7-15-2-1-11-22-15/h4-6,8-10,12,15,22H,1-3,7,11H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	-57.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240675 (US9416127, 12) Show SMILES Clc1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18ClN5O2/c20-14-2-1-3-16(10-14)25-22-11-17(24-25)19(26)23-15-6-4-13(5-7-15)18-12-21-8-9-27-18/h1-7,10-11,18,21H,8-9,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	-57.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240677 (US9416127, 14 | US9416127, 15) Show SMILES FC(F)(F)Oc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O3/c21-20(22,23)31-16-7-5-15(6-8-16)28-25-11-17(27-28)19(29)26-14-3-1-13(2-4-14)18-12-24-9-10-30-18/h1-8,11,18,24H,9-10,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	-57.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240669 (US9416127, 6) Show SMILES Clc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18ClN5O2/c20-14-3-7-16(8-4-14)25-22-11-17(24-25)19(26)23-15-5-1-13(2-6-15)18-12-21-9-10-27-18/h1-8,11,18,21H,9-10,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240670 (US9416127, 7) Show SMILES Cc1nn(nc1C(=O)Nc1ccc(cc1)[C@@H]1CNCCO1)-c1ccccc1 |r| Show InChI InChI=1S/C20H21N5O2/c1-14-19(24-25(23-14)17-5-3-2-4-6-17)20(26)22-16-9-7-15(8-10-16)18-13-21-11-12-27-18/h2-10,18,21H,11-13H2,1H3,(H,22,26)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250212 (US10501411, Example 122 | US11697636, Example 122 ...) Show SMILES FC(F)(F)c1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H21F3N2O2/c21-20(22,23)17-5-1-14(2-6-17)10-12-27-19(26)25-18-7-3-15(4-8-18)16-9-11-24-13-16/h1-8,16,24H,9-13H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250242 (US11697636, Example 152 | US9452980, 152) Show SMILES Clc1ccc(cc1Cl)C(=O)Nc1ccc(cc1)[C@@H]1CCCNC1 |r| Show InChI InChI=1S/C18H18Cl2N2O/c19-16-8-5-13(10-17(16)20)18(23)22-15-6-3-12(4-7-15)14-2-1-9-21-11-14/h3-8,10,14,21H,1-2,9,11H2,(H,22,23)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250218 (US10501411, Example 128 | US11697636, Example 128 ...) Show SMILES Clc1ccc(CCCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H23ClN2O2/c21-18-7-3-15(4-8-18)2-1-13-25-20(24)23-19-9-5-16(6-10-19)17-11-12-22-14-17/h3-10,17,22H,1-2,11-14H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250215 (US10501411, Example 125 | US11697636, Example 125 ...) Show SMILES FC(F)(F)Oc1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H21F3N2O3/c21-20(22,23)28-18-7-1-14(2-8-18)10-12-27-19(26)25-17-5-3-15(4-6-17)16-9-11-24-13-16/h1-8,16,24H,9-13H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190607 (US9181230, 13) Show SMILES Fc1ccc(-c2cc(n[nH]2)-c2ccc(cc2)[C@H]2CNCCO2)c(F)c1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240668 (US9416127, 11 | US9416127, 5) Show SMILES Fc1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18FN5O2/c20-14-2-1-3-16(10-14)25-22-11-17(24-25)19(26)23-15-6-4-13(5-7-15)18-12-21-8-9-27-18/h1-7,10-11,18,21H,8-9,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM167453 (US9073911, 2) Show SMILES Clc1cccc(c1)-c1cc(n[nH]1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240676 (US9416127, 13) Show SMILES FC(F)(F)c1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O2/c21-20(22,23)14-2-1-3-16(10-14)28-25-11-17(27-28)19(29)26-15-6-4-13(5-7-15)18-12-24-8-9-30-18/h1-7,10-11,18,24H,8-9,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250218 (US10501411, Example 128 | US11697636, Example 128 ...) Show SMILES Clc1ccc(CCCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H23ClN2O2/c21-18-7-3-15(4-8-18)2-1-13-25-20(24)23-19-9-5-16(6-10-19)17-11-12-22-14-17/h3-10,17,22H,1-2,11-14H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Rat: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentr...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250215 (US10501411, Example 125 | US11697636, Example 125 ...) Show SMILES FC(F)(F)Oc1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H21F3N2O3/c21-20(22,23)28-18-7-1-14(2-8-18)10-12-27-19(26)25-17-5-3-15(4-6-17)16-9-11-24-13-16/h1-8,16,24H,9-13H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240666 (US9416127, 16 | US9416127, 3) Show SMILES FC(F)Oc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H19F2N5O3/c21-20(22)30-16-7-5-15(6-8-16)27-24-11-17(26-27)19(28)25-14-3-1-13(2-4-14)18-12-23-9-10-29-18/h1-8,11,18,20,23H,9-10,12H2,(H,25,28)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250212 (US10501411, Example 122 | US11697636, Example 122 ...) Show SMILES FC(F)(F)c1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H21F3N2O2/c21-20(22,23)17-5-1-14(2-6-17)10-12-27-19(26)25-18-7-3-15(4-8-18)16-9-11-24-13-16/h1-8,16,24H,9-13H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250218 (US10501411, Example 128 | US11697636, Example 128 ...) Show SMILES Clc1ccc(CCCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H23ClN2O2/c21-18-7-3-15(4-8-18)2-1-13-25-20(24)23-19-9-5-16(6-10-19)17-11-12-22-14-17/h3-10,17,22H,1-2,11-14H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250218 (US10501411, Example 128 | US11697636, Example 128 ...) Show SMILES Clc1ccc(CCCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H23ClN2O2/c21-18-7-3-15(4-8-18)2-1-13-25-20(24)23-19-9-5-16(6-10-19)17-11-12-22-14-17/h3-10,17,22H,1-2,11-14H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240668 (US9416127, 11 | US9416127, 5) Show SMILES Fc1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18FN5O2/c20-14-2-1-3-16(10-14)25-22-11-17(24-25)19(26)23-15-6-4-13(5-7-15)18-12-21-8-9-27-18/h1-7,10-11,18,21H,8-9,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240677 (US9416127, 14 | US9416127, 15) Show SMILES FC(F)(F)Oc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O3/c21-20(22,23)31-16-7-5-15(6-8-16)28-25-11-17(27-28)19(29)26-14-3-1-13(2-4-14)18-12-24-9-10-30-18/h1-8,11,18,24H,9-10,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240673 (US9416127, 10) Show SMILES FC(F)(F)c1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O2/c21-20(22,23)14-3-7-16(8-4-14)28-25-11-17(27-28)19(29)26-15-5-1-13(2-6-15)18-12-24-9-10-30-18/h1-8,11,18,24H,9-10,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240667 (US9416127, 4 | US9416127, 9) Show SMILES Fc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18FN5O2/c20-14-3-7-16(8-4-14)25-22-11-17(24-25)19(26)23-15-5-1-13(2-6-15)18-12-21-9-10-27-18/h1-8,11,18,21H,9-10,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240669 (US9416127, 6) Show SMILES Clc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18ClN5O2/c20-14-3-7-16(8-4-14)25-22-11-17(24-25)19(26)23-15-5-1-13(2-6-15)18-12-21-9-10-27-18/h1-8,11,18,21H,9-10,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190621 (US9181230, 27) Show SMILES Fc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C18H17FN4O/c19-15-5-1-13(2-6-15)17-12-23(22-21-17)16-7-3-14(4-8-16)18-11-20-9-10-24-18/h1-8,12,18,20H,9-11H2/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM60837 (US9181230, 9) Show SMILES Clc1cccc(c1)-c1cc(n[nH]1)-c1ccc(cc1)C1CNCCO1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190602 (US9181230, 8) Show SMILES Clc1ccc(cc1)-c1cc(n[nH]1)-c1ccc(cc1)[C@@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM167466 (US9073911, 15) Show SMILES Clc1cccc(c1)-c1cc([nH]n1)C(=O)Nc1ccc(cc1)[C@@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM167463 (US9073911, 12) Show SMILES Clc1ccc(cc1)-c1cc([nH]n1)C(=O)Nc1ccc(cc1)[C@@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM167453 (US9073911, 2) Show SMILES Clc1cccc(c1)-c1cc(n[nH]1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250210 (US10501411, Example 120 | US11697636, Example 120 ...) Show SMILES Clc1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C19H21ClN2O2/c20-17-5-1-14(2-6-17)10-12-24-19(23)22-18-7-3-15(4-8-18)16-9-11-21-13-16/h1-8,16,21H,9-13H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250240 (US11697636, Example 150 | US9452980, 150) Show SMILES Clc1ccc(cc1Cl)C(=O)Nc1ccc(cc1)[C@H]1CCCNC1 |r| Show InChI InChI=1S/C18H18Cl2N2O/c19-16-8-5-13(10-17(16)20)18(23)22-15-6-3-12(4-7-15)14-2-1-9-21-11-14/h3-8,10,14,21H,1-2,9,11H2,(H,22,23)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250232 (US10501411, Example 142 | US11697636, Example 142 ...) Show SMILES Clc1ccc(cc1)C(=O)Nc1ccc(CCC2CCCN2)cc1 Show InChI InChI=1S/C19H21ClN2O/c20-16-8-6-15(7-9-16)19(23)22-18-11-4-14(5-12-18)3-10-17-2-1-13-21-17/h4-9,11-12,17,21H,1-3,10,13H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250211 (US10501411, Example 121 | US11697636, Example 121 ...) Show SMILES Clc1cccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)c1 Show InChI InChI=1S/C19H21ClN2O2/c20-17-3-1-2-14(12-17)9-11-24-19(23)22-18-6-4-15(5-7-18)16-8-10-21-13-16/h1-7,12,16,21H,8-11,13H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250232 (US10501411, Example 142 | US11697636, Example 142 ...) Show SMILES Clc1ccc(cc1)C(=O)Nc1ccc(CCC2CCCN2)cc1 Show InChI InChI=1S/C19H21ClN2O/c20-16-8-6-15(7-9-16)19(23)22-18-11-4-14(5-12-18)3-10-17-2-1-13-21-17/h4-9,11-12,17,21H,1-3,10,13H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Rat: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentr...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250210 (US10501411, Example 120 | US11697636, Example 120 ...) Show SMILES Clc1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C19H21ClN2O2/c20-17-5-1-14(2-6-17)10-12-24-19(23)22-18-7-3-15(4-8-18)16-9-11-21-13-16/h1-8,16,21H,9-13H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250211 (US10501411, Example 121 | US11697636, Example 121 ...) Show SMILES Clc1cccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)c1 Show InChI InChI=1S/C19H21ClN2O2/c20-17-3-1-2-14(12-17)9-11-24-19(23)22-18-6-4-15(5-7-18)16-8-10-21-13-16/h1-7,12,16,21H,8-11,13H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Rat: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentr...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250110 (US10501411, Example 20 | US11697636, Example 20 | ...) Show SMILES Clc1cccc(c1)C(=O)Nc1ccc(cc1)C1CCNC1 Show InChI InChI=1S/C17H17ClN2O/c18-15-3-1-2-13(10-15)17(21)20-16-6-4-12(5-7-16)14-8-9-19-11-14/h1-7,10,14,19H,8-9,11H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250122 (US10501411, Example 32 | US11697636, Example 32 | ...) Show SMILES CN1CCC(C1)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C18H19ClN2O/c1-21-11-10-15(12-21)13-4-8-17(9-5-13)20-18(22)14-2-6-16(19)7-3-14/h2-9,15H,10-12H2,1H3,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250211 (US10501411, Example 121 | US11697636, Example 121 ...) Show SMILES Clc1cccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)c1 Show InChI InChI=1S/C19H21ClN2O2/c20-17-3-1-2-14(12-17)9-11-24-19(23)22-18-6-4-15(5-7-18)16-8-10-21-13-16/h1-7,12,16,21H,8-11,13H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250147 (US10501411, Example 57 | US11697636, Example 57 | ...) Show SMILES Clc1ccc(cc1)C(=O)Nc1ccc(cc1)C1CCNCC1 Show InChI InChI=1S/C18H19ClN2O/c19-16-5-1-15(2-6-16)18(22)21-17-7-3-13(4-8-17)14-9-11-20-12-10-14/h1-8,14,20H,9-12H2,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Rat: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentr...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM240686 (US9416127, 23) Show SMILES Cc1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H21N5O2/c1-14-3-2-4-17(11-14)25-22-12-18(24-25)20(26)23-16-7-5-15(6-8-16)19-13-21-9-10-27-19/h2-8,11-12,19,21H,9-10,13H2,1H3,(H,23,26)/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250147 (US10501411, Example 57 | US11697636, Example 57 | ...) Show SMILES Clc1ccc(cc1)C(=O)Nc1ccc(cc1)C1CCNCC1 Show InChI InChI=1S/C18H19ClN2O/c19-16-5-1-15(2-6-16)18(22)21-17-7-3-13(4-8-17)14-9-11-20-12-10-14/h1-8,14,20H,9-12H2,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	-55.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250243 (US11697636, Example 153 | US9452980, 153) Show SMILES Clc1cccc(c1)C(=O)Nc1ccc(cc1)[C@@H]1CCCNC1 |r| Show InChI InChI=1S/C18H19ClN2O/c19-16-5-1-3-14(11-16)18(22)21-17-8-6-13(7-9-17)15-4-2-10-20-12-15/h1,3,5-9,11,15,20H,2,4,10,12H2,(H,21,22)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	-55.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250393 (US10501411, Example 303 | US11697636, Example 303 ...) Show SMILES Clc1cccc(NC(=O)Nc2ccc(cc2)C2CNCCO2)c1 Show InChI InChI=1S/C17H18ClN3O2/c18-13-2-1-3-15(10-13)21-17(22)20-14-6-4-12(5-7-14)16-11-19-8-9-23-16/h1-7,10,16,19H,8-9,11H2,(H2,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	-55.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair

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