| Reaction Details |
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 | Report a problem with these data |
| Target | Retinaldehyde-binding protein 1 |
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| Ligand | BDBM338907 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Isomerase Assay |
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| IC50 | <10.00±n/a nM |
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| Citation |  Scott, IL; Kuksa, VA; Gall, A; Orme, MW; Gage, J; Little, Jr., TL; Jiang, Q; Rossiter, LM; McGee, Jr., KF; Kubota, R Styrenyl derivative compounds for treating ophthalmic diseases and disorders US Patent US10201545 Publication Date 2/12/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinaldehyde-binding protein 1 |
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| Name: | Retinaldehyde-binding protein 1 |
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| Synonyms: | CRALBP | Cellular retinaldehyde-binding protein | RLBP1 | RLBP1_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36462.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P12271 |
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| Residue: | 317 |
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| Sequence: | MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETRE
EAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNF
RLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAY
CFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHF
IHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKA
VAEQLFGPQAQAENTAF
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| BDBM338907 |
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| n/a |
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| Name | BDBM338907 |
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| Synonyms: | (E)-1-(3-((1R,2R)-3-amino-1-hydroxy-2- methylpropyl)styryl)cyclohexanol | US10201545, Compound 113 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H27NO2 |
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| Mol. Mass. | 289.4125 |
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| SMILES | C[C@H](CN)[C@@H](O)c1cccc(\C=C\C2(O)CCCCC2)c1 |r| |
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| Structure | 
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