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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Interleukin-1 receptor-associated kinase 4 | ||
| Ligand | BDBM347893 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzymatic Assay | ||
| IC50 | <100±n/a nM | ||
| Citation |  Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K Heteroaryl compounds as IRAK inhibitors and uses thereof US Patent US9790221 Publication Date 10/17/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Interleukin-1 receptor-associated kinase 4 | |||
| Name: | Interleukin-1 receptor-associated kinase 4 | ||
| Synonyms: | IRAK-4 | IRAK4 | IRAK4_HUMAN | Interleukin-1 receptor-associated kinase 4 (IRAK-4) | Interleukin-1 receptor-associated kinase 4 (IRAK4) | Renal carcinoma antigen NY-REN-64 | ||
| Type: | Protein | ||
| Mol. Mass.: | 51519.08 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q9NWZ3 | ||
| Residue: | 460 | ||
| Sequence: |
| ||
| BDBM347893 | |||
| n/a | |||
| Name | BDBM347893 | ||
| Synonyms: | US9790221, Compound 99 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H27ClN8 | ||
| Mol. Mass. | 462.978 | ||
| SMILES | Cn1ccc(n1)-c1cnc(nc1NC1CC(CN)(CCl)C1)-c1cccc(c1)-c1cnn(C)c1 |(-1.69,-7.48,;-2.46,-6.14,;-4,-6.14,;-4.48,-4.67,;-3.23,-3.77,;-1.98,-4.68,;-3.22,-2.23,;-4.56,-1.46,;-4.55,.08,;-3.22,.85,;-1.88,.08,;-1.89,-1.46,;-.56,-2.24,;.78,-1.47,;2.27,-1.87,;2.67,-.39,;3.07,1.1,;4.56,.7,;4.15,-.79,;4.55,-2.28,;1.18,.02,;-3.21,2.39,;-4.54,3.16,;-4.54,4.7,;-3.21,5.47,;-1.87,4.7,;-1.88,3.16,;-.54,5.46,;-.54,7,;.93,7.48,;1.83,6.23,;3.37,6.23,;.92,4.98,)| | ||
| Structure | 
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