Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182699 (US9145392, 400) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0600 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM182489 (US9145392, 190) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182489 (US9145392, 190) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182480 (US9145392, 181) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM182480 (US9145392, 181) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182671 (US9145392, 372) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182551 (US9145392, 252) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182483 (US9145392, 184) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM182699 (US9145392, 400) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182673 (US9145392, 374) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM182551 (US9145392, 252) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182473 (US9145392, 174) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.440 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182535 (US9145392, 236) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182624 (US9145392, 325) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182425 (US9145392, 126) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM182473 (US9145392, 174) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182470 (US9145392, 171) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182586 (US9145392, 287) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182305 (US9145392, 6) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182517 (US9145392, 218) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182409 (US9145392, 110) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM182688 (US9145392, 389) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM182671 (US9145392, 372) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182421 (US9145392, 122) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182481 (US9145392, 182) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182462 (US9145392, 163) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.730 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182678 (US9145392, 379) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182677 (US9145392, 378) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182656 (US9145392, 357) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182615 (US9145392, 316) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182606 (US9145392, 307) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182588 (US9145392, 289) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM224498 (US10080750, Compound 176 | US9321760, 176 | US9662...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com... | US Patent US9662330 (2017) BindingDB Entry DOI: 10.7270/Q2MK6G04 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM182680 (US9145392, 381) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182536 (US9145392, 237) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182504 (US9145392, 205) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM224498 (US10080750, Compound 176 | US9321760, 176 | US9662...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com... | US Patent US9321760 (2016) BindingDB Entry DOI: 10.7270/Q2R78D2R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM182602 (US9145392, 303) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 [T412E] (Homo sapiens (Human)) | BDBM224498 (US10080750, Compound 176 | US9321760, 176 | US9662...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com... | US Patent US10080750 (2018) BindingDB Entry DOI: 10.7270/Q2WS8W9F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM224487 (US10080750, Compound 165 | US9321760, 165 | US9662...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com... | US Patent US9662330 (2017) BindingDB Entry DOI: 10.7270/Q2MK6G04 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 [T412E] (Homo sapiens (Human)) | BDBM224487 (US10080750, Compound 165 | US9321760, 165 | US9662...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com... | US Patent US10080750 (2018) BindingDB Entry DOI: 10.7270/Q2WS8W9F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM182624 (US9145392, 325) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM224487 (US10080750, Compound 165 | US9321760, 165 | US9662...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com... | US Patent US9321760 (2016) BindingDB Entry DOI: 10.7270/Q2R78D2R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182693 (US9145392, 394) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182688 (US9145392, 389) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182669 (US9145392, 370) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182537 (US9145392, 238) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182454 (US9145392, 155) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182408 (US9145392, 109) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human)) | BDBM182378 (US9145392, 79) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... | US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2 | |||||||||||
More data for this Ligand-Target Pair |
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