Reaction Details |
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Target | Trace amine-associated receptor 1 |
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Ligand | BDBM348691 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Radioligand Binding Assay |
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IC50 | 5.20±n/a nM |
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Citation | Cecere, G; Galley, G; Hu, Y; Norcross, R; Pflieger, P; Shen, H 2-oxa-5-azabicyclo[2.2.1]heptan-3-yl derivatives US Patent US9790230 Publication Date 10/17/2017 |
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More Info.: | Get all data from this article, Assay Method |
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Trace amine-associated receptor 1 |
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Name: | Trace amine-associated receptor 1 |
Synonyms: | TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1 |
Type: | Enzyme |
Mol. Mass.: | 38034.73 |
Organism: | Rattus norvegicus (Rat) |
Description: | Q923Y9 |
Residue: | 332 |
Sequence: | MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWL
LHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDR
YYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRG
CFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQ
SKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMV
YAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
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BDBM348691 |
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n/a |
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Name | BDBM348691 |
Synonyms: | (1S,3R,4S)-3-(4-Bromophenyl)-2-oxa-5-azabicyclo[2.2.1]heptane | US9790230, Example 53 |
Type | Small organic molecule |
Emp. Form. | C11H12BrNO |
Mol. Mass. | 254.123 |
SMILES | Brc1ccc(cc1)[C@H]1O[C@@H]2CN[C@H]1C2 |r| |
Structure |
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