| Reaction Details |
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 | Report a problem with these data |
| Target | Trace amine-associated receptor 1 |
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| Ligand | BDBM348727 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Assay |
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| IC50 | 2.60±n/a nM |
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| Citation |  Cecere, G; Galley, G; Hu, Y; Norcross, R; Pflieger, P; Shen, H 2-oxa-5-azabicyclo[2.2.1]heptan-3-yl derivatives US Patent US9790230 Publication Date 10/17/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Trace amine-associated receptor 1 |
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| Name: | Trace amine-associated receptor 1 |
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| Synonyms: | TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 38034.73 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q923Y9 |
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| Residue: | 332 |
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| Sequence: | MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWL
LHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDR
YYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRG
CFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQ
SKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMV
YAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
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| BDBM348727 |
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| n/a |
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| Name | BDBM348727 |
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| Synonyms: | 2-Isopropyl-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-3-yl]phenyl]-5-(2,2,2-trifluoroethoxy)pyrazole-3-carboxamide | US9790230, Example 89 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H25F3N4O3 |
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| Mol. Mass. | 426.4327 |
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| SMILES | CC(C)N\C(=C/C(=N)OCC(F)(F)F)C(=O)Nc1ccc(cc1)[C@@H]1O[C@H]2CN[C@@H]1C2 |r| |
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| Structure | 
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