Reaction Details |
| Report a problem with these data |
Target | Protein tyrosine phosphatase type IVA 3 |
---|
Ligand | BDBM396097 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | In Vitro Biochemical Evaluation |
---|
IC50 | 18.0±14 nM |
---|
Citation | Lazo, JS; Sharlow, ER; McQueeney, KE; Wipf, P; Salamoun, JM Inhibitors of PTP4A3 for the treatment of cancer US Patent US10308663 Publication Date 6/4/2019 |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Protein tyrosine phosphatase type IVA 3 |
---|
Name: | Protein tyrosine phosphatase type IVA 3 |
Synonyms: | PRL3 | PTP4A3 | Protein-tyrosine phosphatase 4A3 | TP4A3_HUMAN |
Type: | PROTEIN |
Mol. Mass.: | 19546.22 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1461022 |
Residue: | 173 |
Sequence: | MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
|
|
|
BDBM396097 |
---|
n/a |
---|
Name | BDBM396097 |
Synonyms: | US10308663, JMS-631-053 |
Type | Small organic molecule |
Emp. Form. | C13H8N2O2S |
Mol. Mass. | 256.28 |
SMILES | N=C1c2sc(cc2C(=O)NC1=O)-c1ccccc1 |
Structure |
|